Team game results -- 2021 Seattle Mariners
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | Decision | Save | Versus | T |
| 4/8/2021 | | @ |  Bal | L | 4-5 | | Paxton | L | Giles | | Hill,R | L |
| 4/8/2021 | | |  ChW | L | 2-4 | | Paxton | L | Paxton | | Puk | L |
| 4/9/2021 | | @ | Bal | W | 4-2 | | Odorizzi | R | Odorizzi | Rogers,Ta | Teheran | R |
| 4/9/2021 | | | ChW | L | 2-4 | | Odorizzi | R | Odorizzi | | Ohtani | R |
| 4/10/2021 | | @ | Bal | L | 0-3 | | Gonzales | L | Gonzales | | Roark | R |
| 4/10/2021 | | | ChW | W | 5-4 | | Gonzales | L | Giles | Rogers,Ta | Wood,A | L |
| 4/11/2021 | | @ | Bal | L | 2-3 | | Samardzija | R | Samardzija | | Foltynewicz | R |
| 4/11/2021 | | | ChW | W | 5-1 | | Samardzija | R | Samardzija | | Porcello | R |
| 4/12/2021 | | |  Oak | L | 5-6 | | Leake | R | Bummer | | Quantrill | R |
| 4/12/2021 | | @ |  Tex | L | 7-9 | 10 | Leake | R | Rogers,Ta | | Manaea | L |
| 4/13/2021 | | | Oak | L | 1-2 | | Paxton | L | Paxton | | Cole,G | R |
| 4/13/2021 | | @ | Tex | L | 4-5 | 10 | Paxton | L | Clippard | | Matz | L |
| 4/14/2021 | | | Oak | W | 3-1 | | Odorizzi | R | Stephenson,R | | Hamels | L |
| 4/14/2021 | | @ | Tex | L | 8-10 | | Odorizzi | R | Giles | | Wacha | R |
| 4/16/2021 | | @ |  KCR | L | 2-7 | | Gonzales | L | Gonzales | | Wilson,Bry | R |
| 4/16/2021 | | |  LAA | W | 2-1 | | Gonzales | L | Gonzales | Rogers,Ta | Keuchel | L |
| 4/17/2021 | | @ | KCR | W | 6-5 | | Samardzija | R | Samardzija | Rogers,Ta | Hudson,Dak | R |
| 4/17/2021 | | | LAA | W | 8-7 | | Samardzija | R | Stephenson,R | | Pineda | R |
| 4/18/2021 | | @ | KCR | W | 9-4 | | Leake | R | Leake | | Fried | L |
| 4/18/2021 | | | LAA | W | 6-1 | | Paxton | L | Paxton | Stephenson,R | Houck | R |
| 4/23/2021 | | |  Hou | L | 6-10 | | Odorizzi | R | Odorizzi | | Suarez,R | L |
| 4/24/2021 | | | Hou | L | 1-3 | | Gonzales | L | Gonzales | | deGrom | R |
| 4/25/2021 | | | Hou | L | 2-5 | | Samardzija | R | Samardzija | | Stroman | R |
| 4/27/2021 | | |  ChC | W | 3-1 | | Paxton | L | Paxton | Rogers,Ta | Norris,D | L |
| 4/28/2021 | | | ChC | W | 9-8 | | Leake | R | Leake | Stephenson,R | Pearson | R |
| 4/29/2021 | | | ChC | L | 3-4 | | Odorizzi | R | Odorizzi | | Smith,Ca | L |
| 5/3/2021 | | @ |  Tor | L | 3-8 | | Odorizzi | R | Odorizzi | | Smyly | L |
| 5/3/2021 | | |  Bos | W | 5-1 | | Odorizzi | R | Odorizzi | | Smeltzer | L |
| 5/4/2021 | | @ | Tor | W | 9-5 | | Gonzales | L | Gonzales | Stammen | Freeland | L |
| 5/4/2021 | | | Bos | W | 4-1 | | Gonzales | L | Gonzales | Rogers,Ta | Margevicius | L |
| 5/5/2021 | | @ | Tor | L | 4-8 | | Samardzija | R | Samardzija | | Reid-Foley | R |
| 5/5/2021 | | | Bos | W | 4-3 | | Samardzija | R | Samardzija | Rogers,Ta | Clarke | R |
| 5/6/2021 | | @ | Tor | L | 4-5 | | Paxton | L | Paxton | | Yamaguchi | R |
| 5/6/2021 | | | Bos | L | 2-4 | | Paxton | L | Paxton | | Rodriguez,E | L |
| 5/7/2021 | | @ |  Pit | W | 8-2 | | Leake | R | Leake | | Senzatela | R |
| 5/8/2021 | | @ | Pit | W | 4-1 | | Odorizzi | R | Odorizzi | Rogers,Ta | Plesac | R |
| 5/9/2021 | | @ | Pit | W | 6-5 | | Gonzales | L | Stephenson,R | Rogers,Ta | Bolanos | R |
| 5/11/2021 | | @ |  Phi | W | 10-5 | | Paxton | L | Paxton | | Bieber | R |
| 5/12/2021 | | @ | Phi | L | 5-9 | | Leake | R | Leake | | Chirinos,Y | R |
| 5/13/2021 | | @ | Phi | L | 3-8 | | Odorizzi | R | Odorizzi | | Castillo,L | R |
| 5/24/2021 | | @ |  Min | L | 3-8 | | Gonzales | L | Gonzales | | Lauer | L |
| 5/24/2021 | | |  Was | W | 7-1 | | Gonzales | L | Gonzales | | McKay,B | L |
| 5/25/2021 | | @ | Min | W | 4-0 | | Leake | R | Leake | | Gallen | R |
| 5/25/2021 | | | Was | W | 3-2 | | Leake | R | Leake | Rogers,Ta | Pivetta | R |
| 5/26/2021 | | @ | Min | L | 3-4 | 10 | Paxton | L | Stephenson,R | | Ray,R | L |
| 5/26/2021 | | | Was | L | 1-3 | | Paxton | L | Wittgren | | Kuhl | R |
| 5/27/2021 | | @ | Min | L | 4-7 | | Odorizzi | R | Odorizzi | | Rasmussen | R |
| 5/27/2021 | | | Was | L | 1-3 | 10 | Odorizzi | R | Bummer | | Barria | R |
| 5/28/2021 | | @ | Oak | L | 2-5 | | Samardzija | R | Samardzija | | Quantrill | R |
| 5/28/2021 | | | Tex | W | 7-2 | | Samardzija | R | Samardzija | | Manaea | L |
| 5/29/2021 | | @ | Oak | W | 4-2 | | Gonzales | L | Gonzales | Rogers,Ta | Walker,T | R |
| 5/29/2021 | | | Tex | L | 4-7 | | Gonzales | L | Rogers,Ta | | Agrazal | R |
| 5/30/2021 | | @ | Oak | W | 10-5 | 10 | Leake | R | Stephenson,R | | Eickhoff | R |
| 5/30/2021 | | | Tex | L | 2-7 | | Leake | R | Leake | | King | R |
| 6/1/2021 | | @ | ChW | W | 7-4 | | Paxton | L | Paxton | Rogers,Ta | Lester,Jon | L |
| 6/1/2021 | | |  NYY | W | 2-1 | | Paxton | L | Paxton | Rogers,Ta | Flaherty,J | R |
| 6/2/2021 | | @ | ChW | W | 6-5 | | Odorizzi | R | Stephenson,R | Rogers,Ta | Porcello | R |
| 6/2/2021 | | | NYY | L | 2-5 | | Odorizzi | R | Odorizzi | | Bundy | R |
| 6/3/2021 | | @ | ChW | L | 3-9 | | Samardzija | R | Samardzija | | Giolito | R |
| 6/3/2021 | | | NYY | L | 4-5 | | Samardzija | R | Wittgren | | Javier | R |
| 6/4/2021 | | @ | ChW | L | 3-9 | | Gonzales | L | Gonzales | | Bassitt | R |
| 6/4/2021 | | | NYY | L | 1-4 | | Gonzales | L | Gonzales | | Minor | L |
| 6/8/2021 | | |  Mil | L | 2-6 | | Leake | R | Leake | | Darvish | R |
| 6/9/2021 | | | Mil | W | 7-2 | | Paxton | L | Wittgren | | Kopech | R |
| 6/10/2021 | | | Mil | L | 1-8 | | Odorizzi | R | Odorizzi | | Kelly,M | R |
| 6/11/2021 | | |  StL | L | 0-5 | | Gonzales | L | Gonzales | | Velasquez | R |
| 6/12/2021 | | | StL | L | 4-5 | | Samardzija | R | Rogers,Ta | | Heaney | L |
| 6/13/2021 | | | StL | L | 3-6 | | Leake | R | Leake | | Bedrosian | R |
| 6/15/2021 | | |  Cin | W | 6-4 | | Paxton | L | Wittgren | Rogers,Ta | Peralta,F | R |
| 6/16/2021 | | | Cin | L | 2-6 | | Odorizzi | R | Odorizzi | | Bauer | R |
| 6/17/2021 | | | Cin | L | 3-6 | | Gonzales | L | Gonzales | | Banda | L |
| 6/18/2021 | | @ |  NYM | W | 8-3 | | Leake | R | Leake | | Anderson,I | R |
| 6/19/2021 | | @ | NYM | W | 5-1 | | Paxton | L | Stammen | Rogers,Ta | Cueto | R |
| 6/20/2021 | | @ | NYM | W | 3-1 | | Odorizzi | R | Odorizzi | Devenski | Means | L |
| 6/22/2021 | | @ |  Mia | W | 9-6 | 10 | Gonzales | L | Devenski | Rogers,Ta | Wright,K | R |
| 6/23/2021 | | @ | Mia | L | 2-8 | | Samardzija | R | Samardzija | | Weaver | R |
| 6/24/2021 | | @ | Mia | W | 4-3 | | Leake | R | Leake | Devenski | Manning | R |
| 6/25/2021 | | @ |  Atl | L | 0-3 | | Paxton | L | Paxton | | Santana,Er | R |
| 6/26/2021 | | @ | Atl | W | 7-4 | | Odorizzi | R | Odorizzi | Rogers,Ta | Soroka | R |
| 6/27/2021 | | @ | Atl | L | 2-9 | | Gonzales | L | Gonzales | | Marquez | R |
| 7/15/2021 | | | Tor | W | 9-2 | | Dunn,J | R | Dunn,J | | Smyly | L |
| 7/15/2021 | | @ | Was | L | 1-9 | | Dunn,J | R | Dunn,J | | Eflin | R |
| 7/16/2021 | | | Tor | W | 8-5 | | Odorizzi | R | Odorizzi | Rogers,Ta | Reid-Foley | R |
| 7/16/2021 | | @ | Was | W | 11-9 | 10 | Odorizzi | R | Rogers,Ta | Bummer | Duplantier | R |
| 7/17/2021 | | | Tor | W | 7-4 | | Leake | R | Leake | Stammen | Supak | R |
| 7/17/2021 | | @ | Was | L | 4-10 | | Leake | R | Leake | | Kuhl | R |
| 7/18/2021 | | | Tor | W | 2-1 | | Samardzija | R | Samardzija | Rogers,Ta | Freeland | L |
| 7/18/2021 | | @ | Was | W | 7-4 | | Samardzija | R | Samardzija | | Burnes | R |
| 7/19/2021 | | @ | LAA | L | 6-9 | | Gonzales | L | Gonzales | | Akin | L |
| 7/19/2021 | | | KCR | W | 5-1 | | Gonzales | L | Gonzales | Rogers,Ta | Wilson,Bry | R |
| 7/20/2021 | | @ | LAA | W | 7-4 | | Dunn,J | R | Dunn,J | Rogers,Ta | Keuchel | L |
| 7/20/2021 | | | KCR | L | 3-11 | | Dunn,J | R | Dunn,J | | Fried | L |
| 7/21/2021 | | @ | LAA | L | 2-5 | | Odorizzi | R | Odorizzi | | Williams,Tr | R |
| 7/21/2021 | | | KCR | W | 1-0 | | Odorizzi | R | Odorizzi | Rogers,Ta | Quintana,J | L |
| 7/23/2021 | | @ | NYY | W | 8-2 | | Samardzija | R | Samardzija | | Minor | L |
| 7/23/2021 | | |  Cle | W | 2-0 | | Samardzija | R | Samardzija | Rogers,Ta | Keller, Brad | R |
| 7/24/2021 | | @ | NYY | W | 3-1 | | Leake | R | Leake | Rogers,Ta | Lamet | R |
| 7/24/2021 | | | Cle | L | 4-9 | | Leake | R | Bummer | | Keller, Mitch | R |
| 7/25/2021 | | @ | NYY | L | 3-4 | | Dunn,J | R | Wittgren | | Flaherty,J | R |
| 7/25/2021 | | | Cle | W | 3-1 | | Dunn,J | R | Stephenson,R | Rogers,Ta | Woodruff | R |
| 7/26/2021 | | @ | NYY | L | 2-10 | | Gonzales | L | Gonzales | | Bundy | R |
| 7/26/2021 | | | Cle | L | 2-5 | | Gonzales | L | Gonzales | | Honeywell | R |
| 8/6/2021 | | @ | KCR | W | 9-5 | | Odorizzi | R | Odorizzi | | Quintana,J | L |
| 8/6/2021 | | | LAA | W | 16-2 | | Odorizzi | R | Odorizzi | | Hearn | L |
| 8/7/2021 | | @ | KCR | W | 3-2 | | Samardzija | R | Samardzija | Rogers,Ta | Newsome | R |
| 8/7/2021 | | | LAA | L | 4-8 | | Samardzija | R | Samardzija | | Houck | R |
| 8/8/2021 | | @ | KCR | L | 2-3 | | Dunn,J | R | Dunn,J | | Hudson,Dak | R |
| 8/8/2021 | | | LAA | W | 5-3 | 13 | Dunn,J | R | Wittgren | | Akin | L |
| 8/9/2021 | | | Oak | W | 6-3 | | Hernandez,F | R | Hernandez,F | Rogers,Ta | Abreu,B | R |
| 8/9/2021 | | @ | Tex | W | 1-0 | | Hernandez,F | R | Hernandez,F | Rogers,Ta | Agrazal | R |
| 8/10/2021 | | | Oak | L | 3-6 | | Leake | R | Leake | | Quantrill | R |
| 8/10/2021 | | @ | Tex | W | 9-7 | | Leake | R | Leake | Rogers,Ta | Manaea | L |
| 8/11/2021 | | | Oak | W | 3-2 | | Odorizzi | R | Wittgren | | Cole,G | R |
| 8/11/2021 | | @ | Tex | W | 9-3 | | Odorizzi | R | Odorizzi | | Faedo | R |
| 8/13/2021 | | @ |  Det | L | 2-9 | | Dunn,J | R | Dunn,J | | Happ,J.A. | L |
| 8/13/2021 | | | Bal | W | 11-4 | | Dunn,J | R | Dunn,J | | Teheran | R |
| 8/14/2021 | | @ | Det | L | 2-3 | | Hernandez,F | R | Hernandez,F | | Rogers,Tr | L |
| 8/14/2021 | | | Bal | L | 9-10 | | Hernandez,F | R | Bummer | | Dunning | R |
| 8/15/2021 | | @ | Det | L | 3-4 | | Leake | R | Rogers,Ta | | Duffy,D | L |
| 8/15/2021 | | | Bal | L | 5-6 | | Leake | R | Leake | | Foltynewicz | R |
| 8/16/2021 | | @ | Det | W | 4-2 | | Odorizzi | R | Giles | Rogers,Ta | Perez,Ma | L |
| 8/16/2021 | | | Bal | W | 4-0 | | Odorizzi | R | Odorizzi | | Yamamoto | R |
| 8/23/2021 | | @ | Bos | W | 4-2 | | Romero,J | L | Romero,J | Clippard | Smeltzer | L |
| 8/23/2021 | | | Det | W | 7-5 | | Romero,J | L | Stammen | Clippard | Rogers,Tr | L |
| 8/24/2021 | | @ | Bos | W | 7-2 | | Dunn,J | R | Dunn,J | | Bettis | R |
| 8/24/2021 | | | Det | L | 2-7 | | Dunn,J | R | Dunn,J | | Sheffield,Ju | L |
| 8/25/2021 | | @ | Bos | W | 11-6 | | Hernandez,F | R | Hernandez,F | | Margevicius | L |
| 8/25/2021 | | | Det | L | 2-3 | | Hernandez,F | R | Lockett | | Salazar | R |
| 8/26/2021 | | @ | Bos | L | 5-6 | | Samardzija | R | Samardzija | | Clarke | R |
| 8/26/2021 | | | Det | W | 8-1 | | Samardzija | R | Samardzija | | Fulmer,M | R |
| 8/27/2021 | | @ |  Mtl | L | 6-12 | | Leake | R | Leake | | Strahm | L |
| 8/27/2021 | | | Min | L | 1-6 | | Leake | R | Leake | | Paddack | R |
| 8/28/2021 | | @ | Mtl | L | 0-1 | | Romero,J | L | Romero,J | | Bumgarner | L |
| 8/28/2021 | | | Min | L | 2-8 | | Romero,J | L | Romero,J | | Lauer | L |
| 8/29/2021 | | @ | Mtl | L | 3-10 | | Dunn,J | R | Dunn,J | | Anderson,Bre | L |
| 8/29/2021 | | | Min | L | 3-4 | 10 | Dunn,J | R | Clippard | | Turnbull | R |
| 8/30/2021 | | @ | Mtl | L | 2-7 | | Hernandez,F | R | Hernandez,F | | Dobnak | R |
| 8/30/2021 | | | Min | L | 8-11 | | Hernandez,F | R | Hernandez,F | | Ray,R | L |
| 9/7/2021 | | @ | Oak | L | 1-3 | | Gonzales | L | Gonzales | | Cole,G | R |
| 9/7/2021 | | | Tex | L | 0-6 | | Gonzales | L | Gonzales | | Faedo | R |
| 9/8/2021 | | @ | Oak | L | 3-16 | | Canning | R | Canning | | Hamels | L |
| 9/8/2021 | | | Tex | W | 4-3 | 14 | Canning | R | Stephenson,R | | Hoffman | R |
| 9/9/2021 | | @ | Oak | L | 3-4 | 12 | Samardzija | R | Stephenson,R | | Quantrill | R |
| 9/9/2021 | | | Tex | W | 9-3 | | Samardzija | R | Samardzija | | Matz | L |
| 9/10/2021 | | @ | Cle | L | 2-13 | | Hernandez,F | R | Hernandez,F | | Keller, Mitch | R |
| 9/10/2021 | | | Mtl | L | 4-6 | | Hernandez,F | R | Hernandez,F | | Dobnak | R |
| 9/11/2021 | | @ | Cle | W | 8-0 | | Dunn,J | R | Dunn,J | | Keller, Brad | R |
| 9/11/2021 | | | Mtl | L | 5-8 | | Dunn,J | R | Dunn,J | | Anderson,Bre | L |
| 9/12/2021 | | @ | Cle | L | 0-8 | | Gonzales | L | Gonzales | | Hendricks | R |
| 9/12/2021 | | | Mtl | W | 7-6 | 11 | Gonzales | L | Warren,Ar | | Lopez,P | R |
| 9/13/2021 | | @ | Cle | L | 3-10 | | Canning | R | Canning | | Verlander | R |
| 9/13/2021 | | | Mtl | W | 3-2 | | Canning | R | Wittgren | Otero | Bumgarner | L |
| 9/24/2021 | | @ | LAA | L | 1-7 | | Samardzija | R | Samardzija | | Hearn | L |
| 9/24/2021 | | | KCR | W | 6-4 | | Samardzija | R | Wittgren | | Newsome | R |
| 9/25/2021 | | @ | LAA | W | 6-1 | | Hernandez,F | R | Otero | | Pineda | R |
| 9/25/2021 | | | KCR | L | 4-8 | | Hernandez,F | R | Hernandez,F | | Davies | R |
| 9/26/2021 | | @ | LAA | W | 7-1 | | Dunn,J | R | Dunn,J | | Akin | L |
| 9/26/2021 | | | KCR | W | 5-2 | | Dunn,J | R | Dunn,J | Clippard | Hudson,Dak | R |
| 9/27/2021 | | @ | Oak | W | 4-2 | | Gonzales | L | Gonzales | Warren,Ar | Cotton | R |
| 9/27/2021 | | | Oak | W | 2-1 | 10 | Gonzales | L | Clippard | | Cole,G | R |
| 9/28/2021 | | @ | Oak | L | 2-10 | | Leake | R | Leake | | Wainwright | R |
| 9/28/2021 | | | Oak | L | 3-9 | | Canning | R | Canning | | Quantrill | R |
| Other |
| Game information | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | | W | L | Pct | L10 | Strk | Gm# |
| 4/8/2021 | | @ | Bal | L | | 4 | 5 | | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/8/2021 | | | ChW | L | | 2 | 4 | | 0 | 2 | .000 | 0-2 | L2 | 2 |
| 4/9/2021 | | @ | Bal | W | Betts | 4 | 2 | | 1 | 2 | .333 | 1-2 | W1 | 3 |
| 4/9/2021 | | | ChW | L | | 2 | 4 | | 1 | 3 | .250 | 1-3 | L1 | 4 |
| 4/10/2021 | | @ | Bal | L | | 0 | 3 | | 1 | 4 | .200 | 1-4 | L2 | 5 |
| 4/10/2021 | | | ChW | W | Santana,Do | 5 | 4 | | 2 | 4 | .333 | 2-4 | W1 | 6 |
| 4/11/2021 | | @ | Bal | L | | 2 | 3 | | 2 | 5 | .286 | 2-5 | L1 | 7 |
| 4/11/2021 | | | ChW | W | Guillorme | 5 | 1 | | 3 | 5 | .375 | 3-5 | W1 | 8 |
| 4/12/2021 | | | Oak | L | | 5 | 6 | | 3 | 6 | .333 | 3-6 | L1 | 9 |
| 4/12/2021 | | @ | Tex | L | | 7 | 9 | | 3 | 7 | .300 | 3-7 | L2 | 10 |
| 4/13/2021 | | | Oak | L | | 1 | 2 | | 3 | 8 | .273 | 3-7 | L3 | 11 |
| 4/13/2021 | | @ | Tex | L | | 4 | 5 | | 3 | 9 | .250 | 3-7 | L4 | 12 |
| 4/14/2021 | | | Oak | W | Santana,Do | 3 | 1 | | 4 | 9 | .308 | 3-7 | W1 | 13 |
| 4/14/2021 | | @ | Tex | L | | 8 | 10 | | 4 | 10 | .286 | 3-7 | L1 | 14 |
| 4/16/2021 | | @ | KCR | L | | 2 | 7 | | 4 | 11 | .267 | 3-7 | L2 | 15 |
| 4/16/2021 | | | LAA | W | Santana,Do | 2 | 1 | | 5 | 11 | .313 | 3-7 | W1 | 16 |
| 4/17/2021 | | @ | KCR | W | Santana,Do | 6 | 5 | | 6 | 11 | .353 | 4-6 | W2 | 17 |
| 4/17/2021 | | | LAA | W | Betts | 8 | 7 | | 7 | 11 | .389 | 4-6 | W3 | 18 |
| 4/18/2021 | | @ | KCR | W | Lindor | 9 | 4 | | 8 | 11 | .421 | 5-5 | W4 | 19 |
| 4/18/2021 | | | LAA | W | Betts | 6 | 1 | | 9 | 11 | .450 | 6-4 | W5 | 20 |
| 4/23/2021 | | | Hou | L | | 6 | 10 | | 9 | 12 | .429 | 6-4 | L1 | 21 |
| 4/24/2021 | | | Hou | L | | 1 | 3 | | 9 | 13 | .409 | 6-4 | L2 | 22 |
| 4/25/2021 | | | Hou | L | | 2 | 5 | | 9 | 14 | .391 | 5-5 | L3 | 23 |
| 4/27/2021 | | | ChC | W | Cron,C.J. | 3 | 1 | | 10 | 14 | .417 | 6-4 | W1 | 24 |
| 4/28/2021 | | | ChC | W | Lindor | 9 | 8 | | 11 | 14 | .440 | 7-3 | W2 | 25 |
| 4/29/2021 | | | ChC | L | | 3 | 4 | | 11 | 15 | .423 | 6-4 | L1 | 26 |
| 5/3/2021 | | @ | Tor | L | | 3 | 8 | | 11 | 16 | .407 | 5-5 | L2 | 27 |
| 5/3/2021 | | | Bos | W | Wynns | 5 | 1 | | 12 | 16 | .429 | 5-5 | W1 | 28 |
| 5/4/2021 | | @ | Tor | W | Wynns | 9 | 5 | | 13 | 16 | .448 | 5-5 | W2 | 29 |
| 5/4/2021 | | | Bos | W | Cron,C.J. | 4 | 1 | | 14 | 16 | .467 | 5-5 | W3 | 30 |
| 5/5/2021 | | @ | Tor | L | | 4 | 8 | | 14 | 17 | .452 | 5-5 | L1 | 31 |
| 5/5/2021 | | | Bos | W | Newman | 4 | 3 | | 15 | 17 | .469 | 6-4 | W1 | 32 |
| 5/6/2021 | | @ | Tor | L | | 4 | 5 | | 15 | 18 | .455 | 6-4 | L1 | 33 |
| 5/6/2021 | | | Bos | L | | 2 | 4 | | 15 | 19 | .441 | 5-5 | L2 | 34 |
| 5/7/2021 | | @ | Pit | W | Bird,G | 8 | 2 | | 16 | 19 | .457 | 5-5 | W1 | 35 |
| 5/8/2021 | | @ | Pit | W | Bird,G | 4 | 1 | | 17 | 19 | .472 | 6-4 | W2 | 36 |
| 5/9/2021 | | @ | Pit | W | Santana,Do | 6 | 5 | | 18 | 19 | .486 | 7-3 | W3 | 37 |
| 5/11/2021 | | @ | Phi | W | Betts | 10 | 5 | | 19 | 19 | .500 | 7-3 | W4 | 38 |
| 5/12/2021 | | @ | Phi | L | | 5 | 9 | | 19 | 20 | .487 | 6-4 | L1 | 39 |
| 5/13/2021 | | @ | Phi | L | | 3 | 8 | | 19 | 21 | .475 | 5-5 | L2 | 40 |
| 5/24/2021 | | @ | Min | L | | 3 | 8 | | 19 | 22 | .463 | 5-5 | L3 | 41 |
| 5/24/2021 | | | Was | W | Newman | 7 | 1 | | 20 | 22 | .476 | 5-5 | W1 | 42 |
| 5/25/2021 | | @ | Min | W | Vogt | 4 | 0 | | 21 | 22 | .488 | 6-4 | W2 | 43 |
| 5/25/2021 | | | Was | W | Betts | 3 | 2 | | 22 | 22 | .500 | 7-3 | W3 | 44 |
| 5/26/2021 | | @ | Min | L | | 3 | 4 | | 22 | 23 | .489 | 6-4 | L1 | 45 |
| 5/26/2021 | | | Was | L | | 1 | 3 | | 22 | 24 | .478 | 5-5 | L2 | 46 |
| 5/27/2021 | | @ | Min | L | | 4 | 7 | | 22 | 25 | .468 | 4-6 | L3 | 47 |
| 5/27/2021 | | | Was | L | | 1 | 3 | | 22 | 26 | .458 | 3-7 | L4 | 48 |
| 5/28/2021 | | @ | Oak | L | | 2 | 5 | | 22 | 27 | .449 | 3-7 | L5 | 49 |
| 5/28/2021 | | | Tex | W | Duvall | 7 | 2 | | 23 | 27 | .460 | 4-6 | W1 | 50 |
| 5/29/2021 | | @ | Oak | W | Lindor | 4 | 2 | | 24 | 27 | .471 | 5-5 | W2 | 51 |
| 5/29/2021 | | | Tex | L | | 4 | 7 | | 24 | 28 | .462 | 4-6 | L1 | 52 |
| 5/30/2021 | | @ | Oak | W | Healy | 10 | 5 | | 25 | 28 | .472 | 4-6 | W1 | 53 |
| 5/30/2021 | | | Tex | L | | 2 | 7 | | 25 | 29 | .463 | 3-7 | L1 | 54 |
| 6/1/2021 | | @ | ChW | W | | 7 | 4 | | 26 | 29 | .473 | 4-6 | W1 | 55 |
| 6/1/2021 | | | NYY | W | Cron,C.J. | 2 | 1 | | 27 | 29 | .482 | 5-5 | W2 | 56 |
| 6/2/2021 | | @ | ChW | W | Healy | 6 | 5 | | 28 | 29 | .491 | 6-4 | W3 | 57 |
| 6/2/2021 | | | NYY | L | | 2 | 5 | | 28 | 30 | .483 | 6-4 | L1 | 58 |
| 6/3/2021 | | @ | ChW | L | | 3 | 9 | | 28 | 31 | .475 | 6-4 | L2 | 59 |
| 6/3/2021 | | | NYY | L | | 4 | 5 | | 28 | 32 | .467 | 5-5 | L3 | 60 |
| 6/4/2021 | | @ | ChW | L | | 3 | 9 | | 28 | 33 | .459 | 4-6 | L4 | 61 |
| 6/4/2021 | | | NYY | L | | 1 | 4 | | 28 | 34 | .452 | 4-6 | L5 | 62 |
| 6/8/2021 | | | Mil | L | | 2 | 6 | | 28 | 35 | .444 | 3-7 | L6 | 63 |
| 6/9/2021 | | | Mil | W | Vogt | 7 | 2 | | 29 | 35 | .453 | 4-6 | W1 | 64 |
| 6/10/2021 | | | Mil | L | | 1 | 8 | | 29 | 36 | .446 | 3-7 | L1 | 65 |
| 6/11/2021 | | | StL | L | | 0 | 5 | | 29 | 37 | .439 | 2-8 | L2 | 66 |
| 6/12/2021 | | | StL | L | | 4 | 5 | | 29 | 38 | .433 | 1-9 | L3 | 67 |
| 6/13/2021 | | | StL | L | | 3 | 6 | | 29 | 39 | .426 | 1-9 | L4 | 68 |
| 6/15/2021 | | | Cin | W | Santana,Do | 6 | 4 | | 30 | 39 | .435 | 2-8 | W1 | 69 |
| 6/16/2021 | | | Cin | L | | 2 | 6 | | 30 | 40 | .429 | 2-8 | L1 | 70 |
| 6/17/2021 | | | Cin | L | | 3 | 6 | | 30 | 41 | .423 | 2-8 | L2 | 71 |
| 6/18/2021 | | @ | NYM | W | Lindor | 8 | 3 | | 31 | 41 | .431 | 3-7 | W1 | 72 |
| 6/19/2021 | | @ | NYM | W | Bird,G | 5 | 1 | | 32 | 41 | .438 | 4-6 | W2 | 73 |
| 6/20/2021 | | @ | NYM | W | Cron,C.J. | 3 | 1 | | 33 | 41 | .446 | 4-6 | W3 | 74 |
| 6/22/2021 | | @ | Mia | W | Cron,C.J. | 9 | 6 | | 34 | 41 | .453 | 5-5 | W4 | 75 |
| 6/23/2021 | | @ | Mia | L | | 2 | 8 | | 34 | 42 | .447 | 5-5 | L1 | 76 |
| 6/24/2021 | | @ | Mia | W | Healy | 4 | 3 | | 35 | 42 | .455 | 6-4 | W1 | 77 |
| 6/25/2021 | | @ | Atl | L | | 0 | 3 | | 35 | 43 | .449 | 6-4 | L1 | 78 |
| 6/26/2021 | | @ | Atl | W | Duvall | 7 | 4 | | 36 | 43 | .456 | 6-4 | W1 | 79 |
| 6/27/2021 | | @ | Atl | L | | 2 | 9 | | 36 | 44 | .450 | 6-4 | L1 | 80 |
| 7/15/2021 | | | Tor | W | Desmond | 9 | 2 | | 37 | 44 | .457 | 7-3 | W1 | 81 |
| 7/15/2021 | | @ | Was | L | | 1 | 9 | | 37 | 45 | .451 | 6-4 | L1 | 82 |
| 7/16/2021 | | | Tor | W | Healy | 8 | 5 | | 38 | 45 | .458 | 6-4 | W1 | 83 |
| 7/16/2021 | | @ | Was | W | Wynns | 11 | 9 | | 39 | 45 | .464 | 6-4 | W2 | 84 |
| 7/17/2021 | | | Tor | W | Santana,Do | 7 | 4 | | 40 | 45 | .471 | 6-4 | W3 | 85 |
| 7/17/2021 | | @ | Was | L | | 4 | 10 | | 40 | 46 | .465 | 6-4 | L1 | 86 |
| 7/18/2021 | | | Tor | W | Ervin | 2 | 1 | | 41 | 46 | .471 | 6-4 | W1 | 87 |
| 7/18/2021 | | @ | Was | W | Healy | 7 | 4 | | 42 | 46 | .477 | 7-3 | W2 | 88 |
| 7/19/2021 | | @ | LAA | L | | 6 | 9 | | 42 | 47 | .472 | 6-4 | L1 | 89 |
| 7/19/2021 | | | KCR | W | Newman | 5 | 1 | | 43 | 47 | .478 | 7-3 | W1 | 90 |
| 7/20/2021 | | @ | LAA | W | Newman | 7 | 4 | | 44 | 47 | .484 | 7-3 | W2 | 91 |
| 7/20/2021 | | | KCR | L | | 3 | 11 | | 44 | 48 | .478 | 7-3 | L1 | 92 |
| 7/21/2021 | | @ | LAA | L | | 2 | 5 | | 44 | 49 | .473 | 6-4 | L2 | 93 |
| 7/21/2021 | | | KCR | W | Duvall | 1 | 0 | | 45 | 49 | .479 | 6-4 | W1 | 94 |
| 7/23/2021 | | @ | NYY | W | Desmond | 8 | 2 | | 46 | 49 | .484 | 6-4 | W2 | 95 |
| 7/23/2021 | | | Cle | W | Ervin | 2 | 0 | | 47 | 49 | .490 | 7-3 | W3 | 96 |
| 7/24/2021 | | @ | NYY | W | Vogt | 3 | 1 | | 48 | 49 | .495 | 7-3 | W4 | 97 |
| 7/24/2021 | | | Cle | L | | 4 | 9 | | 48 | 50 | .490 | 6-4 | L1 | 98 |
| 7/25/2021 | | @ | NYY | L | | 3 | 4 | | 48 | 51 | .485 | 6-4 | L2 | 99 |
| 7/25/2021 | | | Cle | W | Lopes,T | 3 | 1 | | 49 | 51 | .490 | 6-4 | W1 | 100 |
| 7/26/2021 | | @ | NYY | L | | 2 | 10 | | 49 | 52 | .485 | 5-5 | L1 | 101 |
| 7/26/2021 | | | Cle | L | | 2 | 5 | | 49 | 53 | .480 | 5-5 | L2 | 102 |
| 8/6/2021 | | @ | KCR | W | Cron,C.J. | 9 | 5 | | 50 | 53 | .485 | 6-4 | W1 | 103 |
| 8/6/2021 | | | LAA | W | Ervin | 16 | 2 | | 51 | 53 | .490 | 6-4 | W2 | 104 |
| 8/7/2021 | | @ | KCR | W | Healy | 3 | 2 | | 52 | 53 | .495 | 6-4 | W3 | 105 |
| 8/7/2021 | | | LAA | L | | 4 | 8 | | 52 | 54 | .491 | 5-5 | L1 | 106 |
| 8/8/2021 | | @ | KCR | L | | 2 | 3 | | 52 | 55 | .486 | 4-6 | L2 | 107 |
| 8/8/2021 | | | LAA | W | Duvall | 5 | 3 | | 53 | 55 | .491 | 5-5 | W1 | 108 |
| 8/9/2021 | | | Oak | W | Vogt | 6 | 3 | | 54 | 55 | .495 | 6-4 | W2 | 109 |
| 8/9/2021 | | @ | Tex | W | Cron,C.J. | 1 | 0 | | 55 | 55 | .500 | 6-4 | W3 | 110 |
| 8/10/2021 | | | Oak | L | | 3 | 6 | | 55 | 56 | .495 | 6-4 | L1 | 111 |
| 8/10/2021 | | @ | Tex | W | Santana,Do | 9 | 7 | | 56 | 56 | .500 | 7-3 | W1 | 112 |
| 8/11/2021 | | | Oak | W | Santana,Do | 3 | 2 | | 57 | 56 | .504 | 7-3 | W2 | 113 |
| 8/11/2021 | | @ | Tex | W | Santana,Do | 9 | 3 | | 58 | 56 | .509 | 7-3 | W3 | 114 |
| 8/13/2021 | | @ | Det | L | | 2 | 9 | | 58 | 57 | .504 | 6-4 | L1 | 115 |
| 8/13/2021 | | | Bal | W | Guillorme | 11 | 4 | | 59 | 57 | .509 | 7-3 | W1 | 116 |
| 8/14/2021 | | @ | Det | L | | 2 | 3 | | 59 | 58 | .504 | 7-3 | L1 | 117 |
| 8/14/2021 | | | Bal | L | | 9 | 10 | | 59 | 59 | .500 | 6-4 | L2 | 118 |
| 8/15/2021 | | @ | Det | L | | 3 | 4 | | 59 | 60 | .496 | 5-5 | L3 | 119 |
| 8/15/2021 | | | Bal | L | | 5 | 6 | | 59 | 61 | .492 | 4-6 | L4 | 120 |
| 8/16/2021 | | @ | Det | W | Santana,Do | 4 | 2 | | 60 | 61 | .496 | 5-5 | W1 | 121 |
| 8/16/2021 | | | Bal | W | Ervin | 4 | 0 | | 61 | 61 | .500 | 5-5 | W2 | 122 |
| 8/23/2021 | | @ | Bos | W | Duvall | 4 | 2 | | 62 | 61 | .504 | 5-5 | W3 | 123 |
| 8/23/2021 | | | Det | W | Desmond | 7 | 5 | | 63 | 61 | .508 | 5-5 | W4 | 124 |
| 8/24/2021 | | @ | Bos | W | Cron,C.J. | 7 | 2 | | 64 | 61 | .512 | 6-4 | W5 | 125 |
| 8/24/2021 | | | Det | L | | 2 | 7 | | 64 | 62 | .508 | 5-5 | L1 | 126 |
| 8/25/2021 | | @ | Bos | W | | 11 | 6 | | 65 | 62 | .512 | 6-4 | W1 | 127 |
| 8/25/2021 | | | Det | L | | 2 | 3 | | 65 | 63 | .508 | 6-4 | L1 | 128 |
| 8/26/2021 | | @ | Bos | L | | 5 | 6 | | 65 | 64 | .504 | 6-4 | L2 | 129 |
| 8/26/2021 | | | Det | W | Wynns | 8 | 1 | | 66 | 64 | .508 | 7-3 | W1 | 130 |
| 8/27/2021 | | @ | Mtl | L | | 6 | 12 | | 66 | 65 | .504 | 6-4 | L1 | 131 |
| 8/27/2021 | | | Min | L | | 1 | 6 | | 66 | 66 | .500 | 5-5 | L2 | 132 |
| 8/28/2021 | | @ | Mtl | L | | 0 | 1 | | 66 | 67 | .496 | 4-6 | L3 | 133 |
| 8/28/2021 | | | Min | L | | 2 | 8 | | 66 | 68 | .493 | 3-7 | L4 | 134 |
| 8/29/2021 | | @ | Mtl | L | | 3 | 10 | | 66 | 69 | .489 | 2-8 | L5 | 135 |
| 8/29/2021 | | | Min | L | | 3 | 4 | | 66 | 70 | .485 | 2-8 | L6 | 136 |
| 8/30/2021 | | @ | Mtl | L | | 2 | 7 | | 66 | 71 | .482 | 1-9 | L7 | 137 |
| 8/30/2021 | | | Min | L | | 8 | 11 | | 66 | 72 | .478 | 1-9 | L8 | 138 |
| 9/7/2021 | | @ | Oak | L | | 1 | 3 | | 66 | 73 | .475 | 1-9 | L9 | 139 |
| 9/7/2021 | | | Tex | L | | 0 | 6 | | 66 | 74 | .471 | 0-10 | L10 | 140 |
| 9/8/2021 | | @ | Oak | L | | 3 | 16 | | 66 | 75 | .468 | 0-10 | L11 | 141 |
| 9/8/2021 | | | Tex | W | Ervin | 4 | 3 | | 67 | 75 | .472 | 1-9 | W1 | 142 |
| 9/9/2021 | | @ | Oak | L | | 3 | 4 | | 67 | 76 | .469 | 1-9 | L1 | 143 |
| 9/9/2021 | | | Tex | W | Newman | 9 | 3 | | 68 | 76 | .472 | 2-8 | W1 | 144 |
| 9/10/2021 | | @ | Cle | L | | 2 | 13 | | 68 | 77 | .469 | 2-8 | L1 | 145 |
| 9/10/2021 | | | Mtl | L | | 4 | 6 | | 68 | 78 | .466 | 2-8 | L2 | 146 |
| 9/11/2021 | | @ | Cle | W | Duvall | 8 | 0 | | 69 | 78 | .469 | 3-7 | W1 | 147 |
| 9/11/2021 | | | Mtl | L | | 5 | 8 | | 69 | 79 | .466 | 3-7 | L1 | 148 |
| 9/12/2021 | | @ | Cle | L | | 0 | 8 | | 69 | 80 | .463 | 3-7 | L2 | 149 |
| 9/12/2021 | | | Mtl | W | Vogt | 7 | 6 | | 70 | 80 | .467 | 4-6 | W1 | 150 |
| 9/13/2021 | | @ | Cle | L | | 3 | 10 | | 70 | 81 | .464 | 4-6 | L1 | 151 |
| 9/13/2021 | | | Mtl | W | Ervin | 3 | 2 | | 71 | 81 | .467 | 4-6 | W1 | 152 |
| 9/24/2021 | | @ | LAA | L | | 1 | 7 | | 71 | 82 | .464 | 4-6 | L1 | 153 |
| 9/24/2021 | | | KCR | W | Gregorius | 6 | 4 | | 72 | 82 | .468 | 4-6 | W1 | 154 |
| 9/25/2021 | | @ | LAA | W | | 6 | 1 | | 73 | 82 | .471 | 5-5 | W2 | 155 |
| 9/25/2021 | | | KCR | L | | 4 | 8 | | 73 | 83 | .468 | 5-5 | L1 | 156 |
| 9/26/2021 | | @ | LAA | W | Duvall | 7 | 1 | | 74 | 83 | .471 | 5-5 | W1 | 157 |
| 9/26/2021 | | | KCR | W | Duvall | 5 | 2 | | 75 | 83 | .475 | 6-4 | W2 | 158 |
| 9/27/2021 | | @ | Oak | W | Guillorme | 4 | 2 | | 76 | 83 | .478 | 7-3 | W3 | 159 |
| 9/27/2021 | | | Oak | W | Bird,G | 2 | 1 | | 77 | 83 | .481 | 7-3 | W4 | 160 |
| 9/28/2021 | | @ | Oak | L | | 2 | 10 | | 77 | 84 | .478 | 7-3 | L1 | 161 |
| 9/28/2021 | | | Oak | L | | 3 | 9 | | 77 | 85 | .475 | 6-4 | L2 | 162 |