League pitching register -- 2010 American League
Regular season -- as of 10/27/2010
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Jeremy Accardo | ChW | mr | 28 | 3.63 | 0 | 0 | 3 | 32 | 0 | 0 | 0 | 22.1 | 18 | 9 | 9 | 14 | 22 | 1 | 0 |
| Alfredo Aceves | Was | mr | 27 | 1.61 | 6 | 2 | 6 | 60 | 0 | 0 | 0 | 100.2 | 58 | 23 | 18 | 11 | 87 | 10 | 7 |
| Nick Adenhart | Bal | sp | 23 | 3.26 | 1 | 2 | 0 | 5 | 5 | 1 | 0 | 30.1 | 24 | 13 | 11 | 12 | 22 | 2 | 4 |
| Jeremy Affeldt* | NYY | mr | 31 | 2.79 | 6 | 5 | 1 | 53 | 0 | 0 | 0 | 58.0 | 43 | 21 | 18 | 28 | 52 | 4 | 10 |
| Matt Albers | Tex | mr | 27 | 5.75 | 1 | 3 | 3 | 45 | 0 | 0 | 0 | 76.2 | 105 | 56 | 49 | 39 | 60 | 5 | 10 |
| Jose Arredondo | Cle | mr | 26 | 6.28 | 1 | 3 | 0 | 31 | 0 | 0 | 0 | 28.2 | 38 | 22 | 20 | 16 | 34 | 4 | 0 |
| Jose Ascanio | Bal | mr | 25 | 5.40 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 8.1 | 7 | 5 | 5 | 2 | 12 | 1 | 0 |
| John Axford | Cle | mr | 27 | 3.38 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 8.0 | 5 | 3 | 3 | 5 | 4 | 1 | 0 |
| Burke Badenhop | KCR | mr | 27 | 4.35 | 2 | 2 | 2 | 32 | 1 | 0 | 0 | 72.1 | 84 | 37 | 35 | 23 | 59 | 4 | 12 |
| Danys Baez | Min | mr | 32 | 2.60 | 7 | 3 | 5 | 53 | 0 | 0 | 0 | 69.1 | 47 | 23 | 20 | 20 | 40 | 7 | 3 |
| Homer Bailey | Tor | sp | 24 | 4.09 | 7 | 9 | 0 | 22 | 22 | 0 | 0 | 127.2 | 136 | 68 | 58 | 46 | 90 | 15 | 7 |
| John Bale* | Sea | mr | 36 | 2.90 | 1 | 1 | 1 | 22 | 0 | 0 | 0 | 31.0 | 23 | 13 | 10 | 20 | 18 | 3 | 4 |
| Josh Banks | Mtl | sp | 27 | 11.08 | 1 | 5 | 0 | 7 | 6 | 0 | 0 | 26.0 | 52 | 32 | 32 | 2 | 6 | 5 | 0 |
| Daniel Bard | Tor | mr | 25 | 5.70 | 1 | 5 | 5 | 45 | 0 | 0 | 0 | 60.0 | 40 | 39 | 38 | 44 | 80 | 9 | 4 |
| Brian Bass | LAA | mr | 28 | 3.84 | 1 | 1 | 2 | 51 | 0 | 0 | 0 | 105.1 | 112 | 47 | 45 | 45 | 74 | 10 | 13 |
| Miguel Batista | Bal | mr | 39 | 5.86 | 0 | 1 | 2 | 52 | 0 | 0 | 0 | 83.0 | 102 | 57 | 54 | 47 | 72 | 6 | 10 |
| Josh Beckett | KCR | sp | 30 | 3.62 | 12 | 12 | 0 | 32 | 32 | 4 | 1 | 213.2 | 217 | 93 | 86 | 63 | 207 | 23 | 19 |
| Joe Beimel* |   | mr | 33 | 3.73 | 1 | 2 | 3 | 49 | 0 | 0 | 0 | 50.2 | 50 | 21 | 21 | 13 | 40 | 5 | 2 |
| Trevor Bell | LAA | sp | 23 | 8.07 | 0 | 4 | 0 | 7 | 7 | 0 | 0 | 32.1 | 53 | 30 | 29 | 18 | 18 | 4 | 7 |
| Kris Benson | Oak | mr | 35 | 8.84 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 36.2 | 47 | 37 | 36 | 18 | 19 | 10 | 2 |
| Brad Bergesen | Tex | sp | 24 | 3.54 | 16 | 6 | 0 | 24 | 24 | 3 | 1 | 165.1 | 163 | 74 | 65 | 35 | 91 | 20 | 23 |
| Jason Berken | Oak | sp | 26 | 5.55 | 1 | 3 | 0 | 5 | 5 | 0 | 0 | 24.1 | 39 | 22 | 15 | 6 | 14 | 5 | 2 |
| Rafael Betancourt | NYY | mr | 35 | 1.62 | 3 | 0 | 2 | 16 | 0 | 0 | 0 | 16.2 | 8 | 4 | 3 | 8 | 20 | 0 | 1 |
| Jerry Blevins* | Mtl | mr | 26 | 3.03 | 0 | 1 | 1 | 24 | 0 | 0 | 0 | 29.2 | 24 | 10 | 10 | 8 | 30 | 2 | 3 |
| Mitchell Boggs | Det | sp | 26 | 9.25 | 2 | 14 | 0 | 21 | 20 | 0 | 0 | 82.2 | 124 | 89 | 85 | 67 | 68 | 7 | 11 |
| Blaine Boyer | ChW | mr | 28 | 5.89 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 18.1 | 20 | 12 | 12 | 12 | 9 | 1 | 1 |
| Dallas Braden* | Mtl | sp | 26 | 4.64 | 7 | 11 | 0 | 26 | 26 | 2 | 0 | 170.2 | 224 | 95 | 88 | 49 | 99 | 11 | 20 |
| Doug Brocail | Det | mr | 43 | 11.62 | 1 | 0 | 0 | 20 | 0 | 0 | 0 | 26.1 | 43 | 39 | 34 | 26 | 19 | 10 | 3 |
| Brian Bruney | ChW | mr | 28 | 3.74 | 0 | 2 | 3 | 33 | 0 | 0 | 0 | 33.2 | 31 | 16 | 14 | 19 | 26 | 7 | 3 |
| Clay Buchholz | Cle | sp | 25 | 4.35 | 10 | 5 | 0 | 20 | 20 | 1 | 0 | 126.1 | 134 | 64 | 61 | 46 | 86 | 14 | 16 |
| Jason Bulger | KCR | mr | 31 | 4.40 | 4 | 4 | 1 | 50 | 0 | 0 | 0 | 71.2 | 63 | 38 | 35 | 30 | 80 | 6 | 9 |
| Madison Bumgarner* | Sea | mr | 20 | 8.04 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 31.1 | 42 | 29 | 28 | 16 | 22 | 9 | 5 |
| Greg Burke | Tex | mr | 27 | 4.61 | 1 | 4 | 1 | 36 | 0 | 0 | 0 | 52.2 | 66 | 27 | 27 | 13 | 39 | 4 | 2 |
| Tim Byrdak* | Bos | mr | 36 | 2.93 | 7 | 4 | 3 | 45 | 0 | 0 | 0 | 67.2 | 35 | 22 | 22 | 33 | 58 | 5 | 3 |
| Kiko Calero | ChW | mr | 35 | 1.26 | 6 | 1 | 13 | 59 | 0 | 0 | 0 | 71.1 | 36 | 12 | 10 | 35 | 83 | 4 | 1 |
| Kevin Cameron | Min | mr | 30 | 0.00 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 6.1 | 5 | 0 | 0 | 1 | 9 | 0 | 0 |
| Shawn Camp | Det | mr | 34 | 3.13 | 5 | 2 | 1 | 56 | 0 | 0 | 0 | 120.2 | 110 | 48 | 42 | 34 | 93 | 7 | 20 |
| Matt Capps | Sea | cl | 26 | 7.11 | 2 | 2 | 1 | 43 | 0 | 0 | 0 | 74.2 | 118 | 62 | 59 | 21 | 61 | 19 | 9 |
| Chris Carpenter | NYY | sp | 35 | 3.11 | 20 | 5 | 0 | 30 | 30 | 9 | 2 | 228.2 | 211 | 87 | 79 | 57 | 181 | 21 | 26 |
| Alberto Castillo* |   | mr | 34 | 5.00 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 9.0 | 12 | 5 | 5 | 5 | 3 | 2 | 1 |
| Brett Cecil* | Tor | sp | 23 | 4.90 | 9 | 9 | 0 | 21 | 21 | 0 | 0 | 115.2 | 128 | 66 | 63 | 48 | 104 | 13 | 12 |
| Jhoulys Chacin | Cle | mr | 22 | 4.81 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 24.1 | 22 | 13 | 13 | 17 | 30 | 2 | 2 |
| Bruce Chen* | Cle | sp | 33 | 6.37 | 1 | 4 | 0 | 25 | 5 | 0 | 0 | 53.2 | 58 | 40 | 38 | 23 | 25 | 12 | 1 |
| Randy Choate* | Min | mr | 34 | 0.47 | 4 | 0 | 1 | 32 | 0 | 0 | 0 | 38.2 | 19 | 3 | 2 | 11 | 30 | 1 | 7 |
| Tyler Clippard | Sea | mr | 25 | 2.72 | 7 | 5 | 0 | 43 | 0 | 0 | 0 | 76.0 | 45 | 28 | 23 | 47 | 98 | 8 | 3 |
| Phil Coke* | Bal | mr | 27 | 3.75 | 5 | 5 | 0 | 58 | 0 | 0 | 0 | 62.1 | 48 | 27 | 26 | 15 | 55 | 12 | 5 |
| Bartolo Colon | Was | sp | 37 | 6.30 | 1 | 8 | 0 | 14 | 14 | 0 | 0 | 80.0 | 92 | 64 | 56 | 25 | 47 | 26 | 6 |
| Roman Colon | Cle | mr | 30 | 4.19 | 5 | 3 | 0 | 42 | 0 | 0 | 0 | 58.0 | 47 | 28 | 27 | 25 | 40 | 6 | 3 |
| Roy Corcoran | Det | mr | 30 | 14.40 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 5.0 | 9 | 8 | 8 | 10 | 2 | 2 | 1 |
| Francisco Cordero | Tex | cl | 35 | 3.42 | 5 | 6 | 17 | 59 | 0 | 0 | 0 | 68.1 | 74 | 30 | 26 | 35 | 53 | 2 | 6 |
| Lance Cormier | Det | mr | 29 | 3.61 | 4 | 3 | 0 | 50 | 0 | 0 | 0 | 97.1 | 88 | 42 | 39 | 29 | 56 | 9 | 5 |
| Kevin Correia | Mtl | sp | 29 | 5.69 | 11 | 16 | 0 | 32 | 32 | 0 | 0 | 183.1 | 220 | 119 | 116 | 68 | 120 | 23 | 14 |
| Juan Cruz | Cle | mr | 31 | 4.60 | 1 | 1 | 0 | 48 | 0 | 0 | 0 | 58.2 | 44 | 30 | 30 | 30 | 55 | 4 | 2 |
| Johnny Cueto | Sea | sp | 24 | 5.71 | 6 | 12 | 0 | 30 | 30 | 2 | 1 | 176.2 | 204 | 116 | 112 | 71 | 133 | 31 | 15 |
| John Danks* | NYY | sp | 25 | 4.23 | 15 | 8 | 0 | 32 | 32 | 1 | 0 | 212.2 | 192 | 108 | 100 | 77 | 185 | 41 | 15 |
| Wade Davis | Min | sp | 24 | 5.49 | 5 | 2 | 0 | 10 | 10 | 1 | 0 | 59.0 | 65 | 38 | 36 | 24 | 63 | 7 | 2 |
| Jorge de la Rosa* | Was | sp | 29 | 3.88 | 15 | 8 | 0 | 32 | 32 | 3 | 1 | 208.2 | 194 | 100 | 90 | 85 | 223 | 22 | 16 |
| Manny Delcarmen | Cle | mr | 28 | 4.23 | 1 | 6 | 43 | 65 | 0 | 0 | 0 | 66.0 | 60 | 35 | 31 | 32 | 36 | 9 | 3 |
| Ryan Dempster | LAA | sp | 33 | 4.67 | 10 | 14 | 0 | 31 | 31 | 1 | 0 | 190.2 | 196 | 110 | 99 | 74 | 167 | 28 | 19 |
| R.A. Dickey | LAA | mr | 35 | 5.24 | 3 | 3 | 0 | 38 | 2 | 0 | 0 | 87.2 | 108 | 53 | 51 | 33 | 63 | 10 | 10 |
| Mark DiFelice | Bos | mr | 33 | 4.15 | 2 | 4 | 2 | 24 | 0 | 0 | 0 | 43.1 | 40 | 22 | 20 | 7 | 40 | 7 | 0 |
| Brendan Donnelly | Bos | mr | 38 | 2.12 | 3 | 0 | 2 | 20 | 0 | 0 | 0 | 29.2 | 24 | 8 | 7 | 4 | 37 | 3 | 1 |
| Octavio Dotel | Bal | mr | 36 | 6.85 | 2 | 3 | 0 | 67 | 0 | 0 | 0 | 64.1 | 75 | 50 | 49 | 40 | 80 | 14 | 4 |
| Scott Downs* | Min | mr | 34 | 2.93 | 2 | 2 | 1 | 42 | 0 | 0 | 0 | 43.0 | 40 | 14 | 14 | 10 | 43 | 3 | 5 |
| Brian Duensing* | Bal | mr | 27 | 3.15 | 5 | 3 | 0 | 12 | 12 | 5 | 1 | 88.2 | 85 | 33 | 31 | 16 | 60 | 6 | 2 |
| Zach Duke* | Tor | sp | 27 | 5.52 | 5 | 15 | 0 | 31 | 30 | 4 | 0 | 189.0 | 245 | 122 | 116 | 52 | 102 | 31 | 18 |
| Scott Elbert* | Cle | mr | 24 | 4.50 | 0 | 1 | 0 | 14 | 0 | 0 | 0 | 16.0 | 14 | 8 | 8 | 3 | 14 | 5 | 2 |
| Kelvim Escobar | Mtl | sp | 34 | 8.88 | 1 | 4 | 0 | 5 | 5 | 0 | 0 | 24.1 | 30 | 24 | 24 | 14 | 20 | 5 | 2 |
| Dana Eveland* | LAA | sp | 26 | 6.58 | 2 | 6 | 0 | 13 | 13 | 0 | 0 | 64.1 | 92 | 52 | 47 | 34 | 39 | 7 | 14 |
| Scott Eyre* | Det | mr | 38 | 4.44 | 1 | 6 | 3 | 40 | 0 | 0 | 0 | 50.2 | 44 | 28 | 25 | 37 | 43 | 4 | 1 |
| Alfredo Figaro | NYY | sp | 25 | 6.00 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 9.0 | 9 | 6 | 6 | 4 | 10 | 2 | 0 |
| Doug Fister | Bos | sp | 26 | 3.80 | 2 | 1 | 0 | 8 | 8 | 1 | 0 | 47.1 | 45 | 20 | 20 | 16 | 23 | 8 | 7 |
| Randy Flores* | Mtl | mr | 34 | 3.86 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.1 | 2 | 2 | 1 | 3 | 2 | 1 | 0 |
| Josh Fogg | Bos | mr | 33 | 2.52 | 2 | 0 | 2 | 22 | 0 | 0 | 0 | 50.0 | 30 | 14 | 14 | 15 | 31 | 7 | 3 |
| Ryan Franklin | LAA | cl | 37 | 2.21 | 5 | 4 | 3 | 50 | 0 | 0 | 0 | 73.1 | 57 | 22 | 18 | 24 | 49 | 5 | 7 |
| Lucas French* | Det | sp | 24 | 8.46 | 1 | 17 | 0 | 21 | 21 | 0 | 0 | 88.1 | 137 | 87 | 83 | 46 | 67 | 18 | 2 |
| Ernesto Frieri | Mtl | mr | 24 | 13.50 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.2 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
| Jaime Garcia* | Sea | mr | 23 | 9.79 | 1 | 4 | 0 | 6 | 6 | 0 | 0 | 26.2 | 33 | 32 | 29 | 24 | 15 | 9 | 5 |
| Matt Garza | Bal | sp | 26 | 4.88 | 12 | 15 | 0 | 32 | 32 | 5 | 2 | 215.2 | 218 | 129 | 117 | 80 | 204 | 30 | 15 |
| Chad Gaudin | Sea | sp | 27 | 4.80 | 14 | 8 | 0 | 33 | 29 | 1 | 0 | 174.1 | 165 | 98 | 93 | 94 | 166 | 14 | 18 |
| Josh Geer | Tex | sp | 27 | 6.29 | 1 | 3 | 0 | 10 | 10 | 0 | 0 | 54.1 | 84 | 40 | 38 | 6 | 24 | 18 | 6 |
| Edgar Gonzalez | NYY | mr | 27 | 8.18 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 11.0 | 12 | 10 | 10 | 5 | 4 | 2 | 2 |
| Gio Gonzalez* | Sea | sp | 24 | 5.65 | 7 | 9 | 0 | 22 | 22 | 0 | 0 | 113.0 | 122 | 79 | 71 | 66 | 125 | 15 | 9 |
| Mike Gonzalez* | Cle | mr | 32 | 2.12 | 6 | 1 | 1 | 55 | 0 | 0 | 0 | 68.0 | 46 | 17 | 16 | 26 | 75 | 5 | 8 |
| Tom Gorzelanny* | Sea | mr | 27 | 4.09 | 3 | 4 | 0 | 13 | 11 | 0 | 0 | 61.2 | 62 | 30 | 28 | 20 | 59 | 9 | 3 |
| Mike Gosling* | Sea | mr | 29 | 4.72 | 1 | 3 | 0 | 13 | 0 | 0 | 0 | 26.2 | 28 | 14 | 14 | 6 | 15 | 7 | 3 |
| Sean Green | ChW | mr | 31 | 5.17 | 3 | 4 | 3 | 52 | 0 | 0 | 0 | 78.1 | 78 | 46 | 45 | 39 | 55 | 8 | 9 |
| Luke Gregerson | Mtl | mr | 26 | 3.38 | 6 | 7 | 6 | 59 | 0 | 0 | 0 | 96.0 | 80 | 36 | 36 | 16 | 118 | 5 | 3 |
| Kevin Gregg | Sea | cl | 32 | 3.21 | 4 | 8 | 21 | 57 | 0 | 0 | 0 | 81.1 | 62 | 30 | 29 | 27 | 72 | 12 | 3 |
| Zack Greinke | Bos | sp | 26 | 2.15 | 19 | 6 | 0 | 33 | 33 | 17 | 7 | 263.2 | 207 | 70 | 63 | 40 | 313 | 12 | 10 |
| Eddie Guardado* | LAA | mr | 39 | 3.89 | 1 | 2 | 0 | 27 | 0 | 0 | 0 | 41.2 | 34 | 21 | 18 | 15 | 33 | 3 | 0 |
| Matt Guerrier | Was | mr | 31 | 1.88 | 6 | 5 | 43 | 65 | 0 | 0 | 0 | 86.0 | 51 | 18 | 18 | 16 | 73 | 7 | 3 |
| Charlie Haeger | Cle | sp | 26 | 2.63 | 5 | 2 | 0 | 7 | 7 | 1 | 1 | 48.0 | 29 | 16 | 14 | 11 | 47 | 8 | 1 |
| Jason Hammel | ChW | sp | 27 | 6.56 | 11 | 13 | 0 | 31 | 30 | 2 | 0 | 186.2 | 256 | 148 | 136 | 42 | 133 | 27 | 16 |
| Mike Hampton* | Cle | sp | 37 | 3.81 | 11 | 9 | 0 | 25 | 25 | 1 | 1 | 149.0 | 144 | 67 | 63 | 43 | 114 | 16 | 13 |
| Joel Hanrahan | Tex | mr | 28 | 8.82 | 3 | 4 | 1 | 48 | 0 | 0 | 0 | 50.0 | 79 | 52 | 49 | 33 | 62 | 4 | 3 |
| Tommy Hanson | Was | sp | 23 | 3.36 | 13 | 5 | 0 | 25 | 25 | 5 | 1 | 168.2 | 141 | 68 | 63 | 56 | 128 | 19 | 19 |
| J.A. Happ* | LAA | sp | 27 | 5.78 | 7 | 12 | 0 | 27 | 27 | 1 | 0 | 152.2 | 164 | 101 | 98 | 67 | 103 | 26 | 10 |
| Aaron Harang | Tor | sp | 32 | 5.65 | 9 | 17 | 0 | 29 | 29 | 2 | 0 | 181.2 | 207 | 121 | 114 | 39 | 143 | 32 | 13 |
| Kevin Hart | Bos | sp | 27 | 2.35 | 1 | 1 | 0 | 7 | 3 | 0 | 0 | 23.0 | 23 | 6 | 6 | 12 | 16 | 1 | 6 |
| Blake Hawksworth | ChW | mr | 27 | 3.00 | 5 | 0 | 4 | 44 | 0 | 0 | 0 | 48.0 | 30 | 16 | 16 | 20 | 28 | 5 | 6 |
| Aaron Heilman | Sea | mr | 31 | 3.40 | 1 | 5 | 9 | 65 | 0 | 0 | 0 | 90.0 | 76 | 35 | 34 | 47 | 80 | 7 | 9 |
| Matt Herges | Min | mr | 40 | 2.08 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 8.2 | 4 | 2 | 2 | 2 | 5 | 1 | 1 |
| David Hernandez | ChW | sp | 25 | 7.44 | 1 | 4 | 0 | 8 | 8 | 0 | 0 | 42.1 | 59 | 36 | 35 | 21 | 29 | 7 | 4 |
| Felix Hernandez | Min | sp | 24 | 3.28 | 21 | 6 | 0 | 34 | 34 | 8 | 2 | 241.1 | 207 | 94 | 88 | 77 | 239 | 10 | 22 |
| Livan Hernandez | Oak | sp | 35 | 6.13 | 6 | 16 | 0 | 31 | 31 | 2 | 0 | 186.1 | 251 | 143 | 127 | 64 | 109 | 28 | 21 |
| Shawn Hill | Det | sp | 29 | 11.12 | 0 | 3 | 0 | 5 | 5 | 0 | 0 | 17.0 | 35 | 22 | 21 | 4 | 13 | 2 | 0 |
| Trevor Hoffman | ChW | cl | 42 | 2.51 | 5 | 5 | 16 | 62 | 0 | 0 | 0 | 64.2 | 46 | 21 | 18 | 16 | 48 | 9 | 4 |
| J.P. Howell* | Bos | mr | 27 | 2.60 | 3 | 5 | 35 | 55 | 0 | 0 | 0 | 69.1 | 46 | 21 | 20 | 23 | 85 | 3 | 7 |
| Tommy Hunter | KCR | sp | 23 | 4.77 | 8 | 9 | 0 | 22 | 22 | 3 | 1 | 143.1 | 146 | 82 | 76 | 36 | 78 | 17 | 19 |
| Edwin Jackson | Min | sp | 26 | 3.32 | 20 | 4 | 0 | 33 | 33 | 4 | 0 | 233.1 | 221 | 94 | 86 | 75 | 167 | 25 | 23 |
| Steven Jackson | Det | mr | 28 | 3.79 | 1 | 4 | 3 | 35 | 0 | 0 | 0 | 57.0 | 44 | 24 | 24 | 35 | 22 | 3 | 4 |
| Zach Jackson* | Mtl | mr | 27 | 11.45 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 11.0 | 22 | 14 | 14 | 4 | 14 | 3 | 0 |
| Chris Jakubauskas | Mtl | mr | 31 | 4.34 | 2 | 4 | 0 | 27 | 12 | 0 | 0 | 112.0 | 121 | 56 | 54 | 27 | 58 | 16 | 11 |
| Bobby Jenks | KCR | cl | 29 | 2.49 | 5 | 1 | 6 | 52 | 0 | 0 | 0 | 61.1 | 50 | 19 | 17 | 14 | 65 | 9 | 6 |
| Waldis Joaquin | ChW | mr | 23 | 6.75 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 8.0 | 11 | 7 | 6 | 7 | 7 | 1 | 0 |
| Jim Johnson | NYY | mr | 27 | 3.12 | 1 | 0 | 1 | 9 | 0 | 0 | 0 | 8.2 | 8 | 3 | 3 | 3 | 6 | 1 | 2 |
| Josh Johnson | Min | sp | 26 | 3.64 | 19 | 8 | 0 | 33 | 33 | 6 | 1 | 229.2 | 207 | 100 | 93 | 73 | 205 | 25 | 14 |
| Jair Jurrjens |   | sp | 24 | 4.79 | 10 | 13 | 0 | 34 | 34 | 2 | 1 | 208.2 | 235 | 118 | 111 | 80 | 136 | 17 | 24 |
| Scott Kazmir* | Bos | sp | 26 | 4.76 | 4 | 9 | 0 | 23 | 23 | 0 | 0 | 130.1 | 146 | 77 | 69 | 60 | 103 | 6 | 14 |
| Kyle Kendrick | Det | mr | 25 | 3.26 | 2 | 3 | 0 | 6 | 6 | 0 | 0 | 38.2 | 45 | 15 | 14 | 12 | 14 | 2 | 5 |
| Hong-Chih Kuo* | Bos | mr | 28 | 2.19 | 2 | 2 | 2 | 27 | 0 | 0 | 0 | 37.0 | 22 | 9 | 9 | 11 | 42 | 2 | 1 |
| John Lackey |   | sp | 31 | 3.66 | 12 | 10 | 0 | 30 | 30 | 3 | 0 | 201.2 | 206 | 89 | 82 | 51 | 163 | 22 | 21 |
| John Lannan* | Was | sp | 25 | 4.65 | 15 | 13 | 0 | 33 | 33 | 6 | 1 | 222.2 | 231 | 121 | 115 | 88 | 92 | 25 | 37 |
| Mat Latos | Bal | sp | 22 | 6.23 | 4 | 6 | 0 | 14 | 14 | 0 | 0 | 78.0 | 98 | 56 | 54 | 44 | 70 | 19 | 2 |
| Brandon League | Min | mr | 27 | 5.22 | 4 | 3 | 1 | 35 | 0 | 0 | 0 | 50.0 | 55 | 30 | 29 | 18 | 48 | 7 | 9 |
| Wade LeBlanc* | NYY | sp | 25 | 5.85 | 5 | 3 | 0 | 13 | 13 | 0 | 0 | 75.1 | 60 | 54 | 49 | 30 | 35 | 23 | 5 |
| Justin Lehr | Tex | sp | 32 | 11.05 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 14.2 | 29 | 19 | 18 | 6 | 8 | 4 | 1 |
| Jensen Lewis | Cle | mr | 26 | 5.28 | 4 | 2 | 1 | 57 | 0 | 0 | 0 | 75.0 | 75 | 52 | 44 | 38 | 80 | 19 | 7 |
| Matt Lindstrom | Sea | cl | 30 | 2.66 | 2 | 2 | 3 | 41 | 0 | 0 | 0 | 71.0 | 64 | 25 | 21 | 28 | 50 | 2 | 6 |
| Scott Linebrink | LAA | mr | 33 | 3.78 | 5 | 2 | 0 | 41 | 0 | 0 | 0 | 64.1 | 62 | 29 | 27 | 17 | 62 | 9 | 8 |
| Francisco Liriano* | Min | sp | 26 | 4.36 | 9 | 6 | 1 | 28 | 21 | 0 | 0 | 126.0 | 126 | 66 | 61 | 69 | 133 | 13 | 8 |
| Kyle Lohse |   | sp | 31 | 5.63 | 9 | 12 | 0 | 29 | 29 | 1 | 0 | 163.0 | 178 | 105 | 102 | 59 | 110 | 34 | 18 |
| Braden Looper | Tex | sp | 35 | 7.49 | 4 | 15 | 0 | 29 | 29 | 2 | 0 | 152.2 | 222 | 131 | 127 | 52 | 72 | 42 | 18 |
| Rodrigo Lopez | Sea | sp | 34 | 6.49 | 2 | 0 | 0 | 15 | 1 | 0 | 0 | 34.2 | 47 | 27 | 25 | 9 | 25 | 6 | 2 |
| Mark Lowe | Bos | mr | 27 | 4.91 | 6 | 2 | 1 | 43 | 0 | 0 | 0 | 66.0 | 67 | 41 | 36 | 36 | 64 | 6 | 6 |
| Paul Maholm* | NYY | sp | 28 | 5.71 | 7 | 9 | 0 | 26 | 26 | 2 | 1 | 149.2 | 195 | 101 | 95 | 50 | 102 | 23 | 22 |
| Robert Manuel | Cle | mr | 26 | 1.42 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 6.1 | 4 | 1 | 1 | 0 | 8 | 0 | 1 |
| Carlos Marmol | Bal | mr | 27 | 2.78 | 3 | 5 | 27 | 53 | 0 | 0 | 0 | 55.0 | 33 | 17 | 17 | 38 | 77 | 1 | 0 |
| Jason Marquis | Was | sp | 31 | 3.87 | 16 | 8 | 0 | 32 | 32 | 5 | 1 | 220.2 | 221 | 109 | 95 | 86 | 97 | 19 | 32 |
| Pedro Martinez | Was | sp | 38 | 5.32 | 6 | 2 | 0 | 13 | 13 | 1 | 1 | 67.2 | 80 | 41 | 40 | 18 | 66 | 10 | 1 |
| Shairon Martis | KCR | sp | 23 | 4.00 | 5 | 2 | 0 | 16 | 15 | 1 | 0 | 83.1 | 70 | 39 | 37 | 47 | 41 | 5 | 9 |
| Justin Masterson | NYY | mr | 25 | 4.61 | 2 | 2 | 3 | 29 | 0 | 0 | 0 | 54.2 | 65 | 28 | 28 | 16 | 51 | 8 | 10 |
| Brian Matusz* | Tex | sp | 23 | 5.30 | 1 | 4 | 0 | 12 | 12 | 1 | 0 | 69.2 | 75 | 45 | 41 | 20 | 58 | 12 | 5 |
| Brandon McCarthy | NYY | sp | 26 | 3.21 | 13 | 2 | 0 | 19 | 19 | 1 | 1 | 115.0 | 99 | 45 | 41 | 32 | 83 | 16 | 10 |
| Kyle McClellan | Bal | mr | 26 | 5.28 | 3 | 7 | 2 | 69 | 0 | 0 | 0 | 75.0 | 63 | 45 | 44 | 44 | 61 | 9 | 14 |
| Seth McClung | Tor | mr | 29 | 5.02 | 2 | 3 | 0 | 48 | 0 | 0 | 0 | 71.2 | 79 | 42 | 40 | 47 | 43 | 13 | 9 |
| Gil Meche | KCR | sp | 31 | 4.05 | 9 | 7 | 0 | 27 | 27 | 1 | 0 | 155.2 | 139 | 82 | 70 | 66 | 119 | 18 | 12 |
| Cla Meredith | LAA | mr | 27 | 6.00 | 4 | 6 | 1 | 51 | 0 | 0 | 0 | 78.0 | 110 | 56 | 52 | 18 | 46 | 15 | 10 |
| Randy Messenger | Det | mr | 28 | 6.75 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 24.0 | 48 | 19 | 18 | 2 | 18 | 6 | 5 |
| Dan Meyer* | NYY | mr | 28 | 2.92 | 0 | 0 | 1 | 18 | 0 | 0 | 0 | 12.1 | 8 | 4 | 4 | 4 | 13 | 1 | 1 |
| Kam Mickolio | ChW | mr | 26 | 3.00 | 1 | 1 | 1 | 23 | 0 | 0 | 0 | 18.0 | 11 | 6 | 6 | 9 | 15 | 0 | 0 |
| Andrew Miller* | LAA | sp | 25 | 6.42 | 7 | 8 | 0 | 20 | 20 | 0 | 0 | 96.2 | 111 | 75 | 69 | 56 | 71 | 5 | 13 |
| Trever Miller* | Was | mr | 37 | 3.12 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 8.2 | 7 | 3 | 3 | 1 | 8 | 1 | 0 |
| Kevin Millwood |   | sp | 35 | 5.18 | 11 | 15 | 0 | 34 | 34 | 1 | 0 | 206.2 | 218 | 124 | 119 | 82 | 122 | 33 | 23 |
| Eric Milton* | Sea | sp | 34 | 4.57 | 6 | 3 | 0 | 10 | 10 | 1 | 0 | 63.0 | 69 | 33 | 32 | 14 | 50 | 5 | 5 |
| Zach Miner | Det | mr | 28 | 6.81 | 0 | 3 | 2 | 36 | 0 | 0 | 0 | 74.0 | 97 | 66 | 56 | 53 | 51 | 10 | 16 |
| Brandon Morrow | NYY | cl | 25 | 4.48 | 7 | 3 | 0 | 20 | 10 | 0 | 0 | 70.1 | 63 | 39 | 35 | 44 | 72 | 8 | 7 |
| Clayton Mortensen | Mtl | sp | 25 | 7.66 | 2 | 6 | 0 | 23 | 8 | 0 | 0 | 49.1 | 53 | 44 | 42 | 30 | 17 | 6 | 7 |
| Charlie Morton | Det | sp | 26 | 7.33 | 5 | 9 | 0 | 22 | 22 | 0 | 0 | 100.2 | 143 | 85 | 82 | 52 | 73 | 14 | 16 |
| Guillermo Mota | NYY | mr | 36 | 3.04 | 3 | 2 | 3 | 45 | 0 | 0 | 0 | 53.1 | 49 | 20 | 18 | 13 | 33 | 6 | 3 |
| Jason Motte | Was | mr | 28 | 7.99 | 1 | 1 | 1 | 39 | 0 | 0 | 0 | 41.2 | 58 | 37 | 37 | 13 | 30 | 9 | 3 |
| Jamie Moyer* | NYY | sp | 47 | 3.60 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 10.0 | 12 | 4 | 4 | 3 | 4 | 0 | 3 |
| Edward Mujica | Min | mr | 26 | 4.58 | 0 | 0 | 1 | 35 | 0 | 0 | 0 | 59.0 | 65 | 31 | 30 | 12 | 52 | 14 | 2 |
| Brett Myers | Oak | sp | 29 | 4.72 | 2 | 8 | 0 | 14 | 14 | 3 | 0 | 87.2 | 85 | 57 | 46 | 34 | 64 | 20 | 7 |
| Chris Narveson* | KCR | mr | 28 | 7.90 | 1 | 1 | 0 | 22 | 4 | 0 | 0 | 49.0 | 66 | 43 | 43 | 27 | 49 | 7 | 0 |
| Joe Nelson | Bos | mr | 35 | 4.93 | 2 | 2 | 2 | 35 | 0 | 0 | 0 | 42.0 | 49 | 24 | 23 | 30 | 41 | 5 | 1 |
| Fu-Te Ni* | Bal | mr | 27 | 4.20 | 1 | 0 | 2 | 37 | 0 | 0 | 0 | 30.0 | 24 | 16 | 14 | 9 | 16 | 5 | 1 |
| Jonathon Niese* | ChW | sp | 23 | 6.53 | 3 | 3 | 0 | 8 | 8 | 0 | 0 | 41.1 | 48 | 31 | 30 | 22 | 37 | 7 | 5 |
| Fernando Nieve | LAA | sp | 27 | 9.00 | 0 | 9 | 0 | 11 | 11 | 0 | 0 | 52.0 | 79 | 54 | 52 | 26 | 37 | 9 | 6 |
| Dustin Nippert | ChW | sp | 29 | 2.37 | 8 | 2 | 3 | 62 | 0 | 0 | 0 | 83.2 | 70 | 24 | 22 | 28 | 57 | 7 | 13 |
| Bud Norris | Tor | sp | 25 | 5.81 | 4 | 4 | 0 | 11 | 10 | 1 | 0 | 57.1 | 57 | 42 | 37 | 32 | 58 | 11 | 3 |
| Hideki Okajima* | Was | mr | 34 | 1.75 | 8 | 3 | 2 | 70 | 0 | 0 | 0 | 72.0 | 48 | 19 | 14 | 22 | 69 | 5 | 5 |
| Garrett Olson* | LAA | mr | 26 | 3.02 | 0 | 1 | 0 | 27 | 1 | 0 | 0 | 50.2 | 34 | 17 | 17 | 22 | 26 | 5 | 7 |
| Russ Ortiz | Sea | sp | 36 | 6.55 | 6 | 5 | 0 | 18 | 17 | 1 | 1 | 88.0 | 120 | 71 | 64 | 35 | 63 | 11 | 13 |
| Vicente Padilla | KCR | sp | 32 | 3.58 | 12 | 9 | 0 | 29 | 29 | 1 | 0 | 183.2 | 186 | 83 | 73 | 56 | 134 | 16 | 26 |
| Jonathan Papelbon | Min | cl | 29 | 1.47 | 4 | 1 | 44 | 61 | 0 | 0 | 0 | 67.1 | 47 | 12 | 11 | 19 | 75 | 4 | 3 |
| Chan Ho Park | NYY | mr | 37 | 3.39 | 4 | 3 | 0 | 29 | 2 | 0 | 0 | 77.0 | 65 | 31 | 29 | 28 | 75 | 10 | 6 |
| Carl Pavano | Bal | sp | 34 | 5.64 | 10 | 18 | 0 | 33 | 32 | 3 | 0 | 213.2 | 282 | 144 | 134 | 53 | 144 | 32 | 29 |
| Jake Peavy | Oak | sp | 29 | 4.57 | 10 | 8 | 0 | 20 | 20 | 5 | 0 | 134.0 | 128 | 70 | 68 | 50 | 141 | 23 | 11 |
| Tony Pena | Oak | mr | 28 | 2.94 | 6 | 5 | 3 | 67 | 0 | 0 | 0 | 95.0 | 102 | 32 | 31 | 27 | 65 | 6 | 12 |
| Hayden Penn | Oak | mr | 25 | 15.43 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 7.0 | 15 | 12 | 12 | 7 | 7 | 2 | 0 |
| Chris Perez | Mtl | mr | 24 | 5.12 | 4 | 5 | 24 | 54 | 0 | 0 | 0 | 58.0 | 59 | 35 | 33 | 26 | 72 | 16 | 6 |
| Oliver Perez* | LAA | sp | 28 | 7.35 | 3 | 9 | 0 | 19 | 19 | 0 | 0 | 89.1 | 91 | 76 | 73 | 85 | 93 | 19 | 3 |
| Glen Perkins* | Oak | sp | 27 | 6.41 | 5 | 11 | 0 | 20 | 20 | 0 | 0 | 119.1 | 183 | 91 | 85 | 25 | 58 | 15 | 19 |
| Joel Pineiro | Bos | sp | 31 | 3.25 | 3 | 2 | 0 | 8 | 8 | 3 | 2 | 61.0 | 65 | 26 | 22 | 3 | 21 | 2 | 6 |
| Rick Porcello | ChW | sp | 21 | 4.05 | 14 | 5 | 0 | 31 | 31 | 2 | 1 | 211.0 | 236 | 103 | 95 | 45 | 135 | 29 | 27 |
| David Purcey* | ChW | sp | 28 | 6.50 | 5 | 6 | 0 | 19 | 19 | 0 | 0 | 88.2 | 106 | 72 | 64 | 58 | 70 | 15 | 5 |
| Horacio Ramirez* | Sea | mr | 30 | 10.32 | 0 | 1 | 0 | 11 | 1 | 0 | 0 | 11.1 | 19 | 15 | 13 | 9 | 3 | 4 | 0 |
| Ramon Ramirez | Oak | mr | 28 | 3.71 | 6 | 5 | 26 | 58 | 0 | 0 | 0 | 70.1 | 66 | 32 | 29 | 24 | 60 | 8 | 6 |
| Ramon Ramirez | Mtl | mr | 27 | 15.85 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 15.1 | 30 | 27 | 27 | 7 | 16 | 12 | 1 |
| Chris Ray | Mtl | mr | 28 | 6.08 | 0 | 0 | 0 | 32 | 0 | 0 | 0 | 47.1 | 68 | 35 | 32 | 17 | 40 | 12 | 5 |
| Robert Ray | Bal | sp | 26 | 4.71 | 2 | 3 | 0 | 6 | 5 | 2 | 0 | 36.1 | 29 | 21 | 19 | 9 | 23 | 5 | 3 |
| Tim Redding | Bos | sp | 32 | 4.35 | 3 | 6 | 1 | 18 | 14 | 0 | 0 | 91.0 | 95 | 47 | 44 | 31 | 59 | 12 | 6 |
| Chad Reineke | Mtl | sp | 28 | 11.57 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 11.2 | 21 | 15 | 15 | 9 | 9 | 3 | 2 |
| Dennys Reyes* | Oak | mr | 33 | 5.29 | 7 | 3 | 4 | 60 | 0 | 0 | 0 | 68.0 | 69 | 44 | 40 | 34 | 60 | 5 | 3 |
| Arthur Rhodes* | Tor | mr | 40 | 2.88 | 1 | 1 | 0 | 53 | 0 | 0 | 0 | 59.1 | 52 | 23 | 19 | 34 | 61 | 2 | 3 |
| Clayton Richard* | Tex | sp | 26 | 5.64 | 8 | 14 | 0 | 30 | 30 | 0 | 0 | 148.1 | 155 | 99 | 93 | 96 | 124 | 23 | 19 |
| Scott Richmond | Min | sp | 30 | 3.22 | 3 | 2 | 0 | 11 | 6 | 1 | 0 | 44.2 | 39 | 16 | 16 | 17 | 47 | 6 | 1 |
| Juan Rincon | NYY | mr | 31 | 3.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.0 | 5 | 2 | 2 | 3 | 5 | 1 | 1 |
| Mariano Rivera | LAA | cl | 40 | 1.22 | 3 | 5 | 24 | 59 | 0 | 0 | 0 | 74.0 | 50 | 10 | 10 | 11 | 82 | 4 | 6 |
| Nate Robertson* | Bos | mr | 32 | 3.28 | 4 | 6 | 0 | 16 | 15 | 1 | 0 | 82.1 | 85 | 38 | 30 | 35 | 56 | 5 | 8 |
| Francisco Rodriguez | Tor | cl | 28 | 1.43 | 5 | 1 | 23 | 52 | 0 | 0 | 0 | 75.1 | 35 | 12 | 12 | 28 | 74 | 7 | 1 |
| Henry Rodriguez | LAA | mr | 23 | 18.90 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 3.1 | 6 | 7 | 7 | 3 | 3 | 0 | 0 |
| Rafael Rodriguez | Tor | mr | 25 | 5.32 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 22.0 | 28 | 13 | 13 | 8 | 8 | 4 | 7 |
| Esmil Rogers | KCR | sp | 24 | 3.75 | 1 | 2 | 0 | 3 | 3 | 0 | 0 | 12.0 | 13 | 10 | 5 | 6 | 6 | 2 | 2 |
| Ricky Romero* | Cle | sp | 25 | 5.29 | 12 | 12 | 0 | 30 | 30 | 2 | 2 | 170.0 | 202 | 111 | 100 | 77 | 131 | 14 | 27 |
| Sergio Romo | Min | mr | 27 | 4.43 | 1 | 5 | 1 | 18 | 0 | 0 | 0 | 22.1 | 23 | 11 | 11 | 14 | 35 | 2 | 1 |
| Carlos Rosa | ChW | mr | 25 | 3.09 | 1 | 0 | 1 | 16 | 0 | 0 | 0 | 11.2 | 11 | 4 | 4 | 5 | 9 | 3 | 0 |
| Leo Rosales | Tor | mr | 29 | 2.36 | 4 | 2 | 0 | 32 | 0 | 0 | 0 | 53.1 | 41 | 15 | 14 | 17 | 40 | 6 | 8 |
| Ryan Rowland-Smith* | Det | sp | 27 | 5.89 | 5 | 7 | 0 | 16 | 16 | 1 | 0 | 84.0 | 93 | 60 | 55 | 30 | 47 | 11 | 5 |
| B.J. Ryan* | Tor | mr | 34 | 10.80 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11.2 | 19 | 14 | 14 | 11 | 9 | 2 | 2 |
| Marc Rzepczynski* | Det | sp | 24 | 3.47 | 3 | 6 | 0 | 14 | 14 | 1 | 0 | 85.2 | 73 | 36 | 33 | 39 | 65 | 11 | 17 |
| C.C. Sabathia* | Oak | sp | 29 | 2.92 | 17 | 6 | 0 | 34 | 34 | 8 | 4 | 262.0 | 229 | 93 | 85 | 68 | 220 | 15 | 31 |
| Brian Sanches | Det | mr | 31 | 2.99 | 3 | 3 | 4 | 48 | 0 | 0 | 0 | 90.1 | 79 | 36 | 30 | 27 | 75 | 10 | 8 |
| Ervin Santana |   | sp | 27 | 5.93 | 5 | 11 | 0 | 27 | 27 | 3 | 0 | 150.1 | 166 | 104 | 99 | 56 | 97 | 28 | 20 |
| Johan Santana* | Sea | sp | 31 | 4.09 | 13 | 9 | 0 | 29 | 29 | 7 | 3 | 220.0 | 196 | 102 | 100 | 56 | 208 | 26 | 15 |
| Dennis Sarfate | NYY | mr | 29 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 4 | 3 | 3 | 1 | 1 | 0 | 0 |
| Joe Saunders* | LAA | sp | 29 | 4.57 | 11 | 13 | 0 | 31 | 31 | 1 | 1 | 181.1 | 192 | 112 | 92 | 60 | 102 | 29 | 20 |
| Max Scherzer | Tor | sp | 25 | 5.87 | 10 | 14 | 0 | 30 | 30 | 1 | 0 | 176.1 | 196 | 117 | 115 | 75 | 189 | 23 | 12 |
| Daniel Schlereth* | Det | mr | 24 | 5.19 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 34.2 | 32 | 22 | 20 | 28 | 51 | 3 | 2 |
| George Sherrill* | KCR | cl | 33 | 2.30 | 5 | 5 | 10 | 63 | 0 | 0 | 0 | 74.1 | 60 | 19 | 19 | 21 | 74 | 3 | 5 |
| Brian Shouse* | Bal | mr | 41 | 4.72 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 13.1 | 21 | 7 | 7 | 5 | 8 | 4 | 4 |
| Tony Sipp* | Cle | mr | 26 | 2.03 | 4 | 0 | 1 | 43 | 0 | 0 | 0 | 44.1 | 21 | 12 | 10 | 25 | 46 | 4 | 3 |
| Doug Slaten* | Tex | mr | 30 | 4.15 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.1 | 4 | 2 | 2 | 1 | 2 | 0 | 1 |
| Kevin Slowey | Tor | sp | 26 | 5.84 | 5 | 7 | 0 | 20 | 20 | 0 | 0 | 115.2 | 145 | 80 | 75 | 30 | 120 | 21 | 5 |
| Joe Smith | Tor | mr | 26 | 4.79 | 2 | 3 | 2 | 31 | 0 | 0 | 0 | 41.1 | 42 | 22 | 22 | 23 | 48 | 6 | 2 |
| John Smoltz | Mtl | sp | 43 | 5.30 | 7 | 11 | 0 | 19 | 19 | 0 | 0 | 108.2 | 135 | 64 | 64 | 32 | 98 | 15 | 3 |
| Ian Snell | Tex | sp | 28 | 5.39 | 11 | 14 | 0 | 31 | 31 | 1 | 0 | 177.0 | 203 | 120 | 106 | 73 | 117 | 18 | 13 |
| Rafael Soriano | NYY | cl | 30 | 2.16 | 6 | 5 | 42 | 58 | 0 | 0 | 0 | 58.1 | 39 | 15 | 14 | 22 | 81 | 4 | 2 |
| Jorge Sosa | Det | mr | 33 | 10.38 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 8 | 8 | 5 | 4 | 3 | 2 | 1 |
| Justin Speier | Mtl | mr | 36 | 6.52 | 0 | 1 | 0 | 33 | 0 | 0 | 0 | 40.0 | 53 | 29 | 29 | 12 | 40 | 12 | 2 |
| Russ Springer | Tor | mr | 41 | 5.73 | 4 | 1 | 2 | 56 | 0 | 0 | 0 | 75.1 | 98 | 49 | 48 | 20 | 76 | 13 | 4 |
| Craig Stammen | Tex | sp | 26 | 4.17 | 10 | 8 | 0 | 23 | 23 | 4 | 1 | 153.1 | 140 | 72 | 71 | 32 | 76 | 24 | 6 |
| Mitch Stetter* | Was | mr | 29 | 5.32 | 1 | 2 | 0 | 32 | 0 | 0 | 0 | 22.0 | 20 | 13 | 13 | 10 | 16 | 1 | 0 |
| Jeff Stevens | Cle | mr | 26 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 2 | 0 | 0 | 1 | 2 | 0 | 0 |
| Brian Stokes | Was | mr | 30 | 3.54 | 3 | 3 | 2 | 56 | 0 | 0 | 0 | 53.1 | 50 | 25 | 21 | 23 | 29 | 4 | 6 |
| Jeff Suppan | Bal | sp | 35 | 7.04 | 7 | 12 | 0 | 28 | 28 | 0 | 0 | 149.2 | 209 | 124 | 117 | 72 | 60 | 24 | 31 |
| Ken Takahashi* | Oak | mr | 41 | 4.74 | 0 | 0 | 1 | 18 | 0 | 0 | 0 | 24.2 | 22 | 14 | 13 | 12 | 26 | 1 | 2 |
| Brian Tallet* | Oak | sp | 32 | 4.87 | 10 | 11 | 0 | 30 | 30 | 0 | 0 | 175.2 | 189 | 103 | 95 | 74 | 148 | 21 | 14 |
| Julian Tavarez | Oak | mr | 37 | 3.76 | 3 | 2 | 0 | 39 | 0 | 0 | 0 | 67.0 | 56 | 32 | 28 | 46 | 49 | 2 | 7 |
| Dale Thayer | Mtl | mr | 29 | 7.71 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 11.2 | 19 | 11 | 10 | 1 | 5 | 3 | 1 |
| Rich Thompson | Mtl | mr | 25 | 6.83 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 27.2 | 47 | 22 | 21 | 6 | 28 | 7 | 3 |
| Brett Tomko | Cle | mr | 37 | 6.04 | 3 | 5 | 0 | 10 | 10 | 0 | 0 | 50.2 | 51 | 36 | 34 | 13 | 27 | 11 | 4 |
| Ramon Troncoso | Tex | mr | 27 | 2.13 | 3 | 3 | 4 | 64 | 0 | 0 | 0 | 101.1 | 92 | 29 | 24 | 34 | 61 | 6 | 13 |
| Jose Valverde | KCR | cl | 30 | 2.55 | 3 | 3 | 31 | 51 | 0 | 0 | 0 | 60.0 | 37 | 17 | 17 | 31 | 58 | 3 | 2 |
| Jason Vargas* | Bal | sp | 27 | 6.09 | 5 | 7 | 0 | 18 | 14 | 0 | 0 | 85.2 | 125 | 65 | 58 | 21 | 58 | 16 | 5 |
| Donald Veal* | LAA | mr | 25 | 5.79 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 9.1 | 9 | 8 | 6 | 10 | 8 | 2 | 2 |
| Justin Verlander | Cle | sp | 27 | 3.47 | 12 | 10 | 0 | 35 | 35 | 3 | 2 | 231.0 | 234 | 93 | 89 | 52 | 270 | 21 | 13 |
| Ron Villone* | Tex | mr | 40 | 4.25 | 0 | 2 | 0 | 38 | 0 | 0 | 0 | 55.0 | 49 | 26 | 26 | 27 | 46 | 4 | 4 |
| Luis Vizcaino | ChW | mr | 35 | 2.50 | 2 | 0 | 2 | 23 | 0 | 0 | 0 | 18.0 | 9 | 5 | 5 | 9 | 10 | 1 | 0 |
| Edinson Volquez | Mtl | sp | 26 | 5.60 | 2 | 8 | 0 | 13 | 13 | 1 | 1 | 72.1 | 76 | 49 | 45 | 46 | 61 | 9 | 6 |
| Chris Volstad | KCR | sp | 23 | 5.10 | 16 | 10 | 0 | 29 | 29 | 0 | 0 | 166.0 | 200 | 100 | 94 | 60 | 113 | 34 | 21 |
| Billy Wagner* | Tor | mr | 38 | 6.39 | 0 | 2 | 3 | 10 | 0 | 0 | 0 | 12.2 | 15 | 9 | 9 | 8 | 25 | 0 | 0 |
| Tim Wakefield | Min | sp | 43 | 3.91 | 13 | 8 | 0 | 25 | 25 | 3 | 0 | 161.0 | 162 | 83 | 70 | 69 | 89 | 18 | 16 |
| Tyler Walker | Min | mr | 34 | 3.31 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 16.1 | 13 | 6 | 6 | 4 | 15 | 1 | 0 |
| Jarrod Washburn* | Bos | sp | 35 | 4.35 | 15 | 11 | 0 | 29 | 29 | 3 | 1 | 184.0 | 194 | 94 | 89 | 47 | 104 | 21 | 22 |
| David Weathers | Oak | mr | 40 | 5.91 | 1 | 3 | 0 | 54 | 0 | 0 | 0 | 85.1 | 77 | 58 | 56 | 44 | 54 | 19 | 9 |
| Jeff Weaver | Was | mr | 33 | 2.60 | 5 | 1 | 1 | 13 | 8 | 1 | 1 | 62.1 | 47 | 22 | 18 | 13 | 51 | 4 | 0 |
| Brandon Webb | NYY | sp | 31 | 20.25 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1.1 | 3 | 3 | 3 | 1 | 1 | 1 | 0 |
| Ryan Webb | Was | mr | 24 | 3.27 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 11.0 | 13 | 5 | 4 | 6 | 6 | 2 | 1 |
| Todd Wellemeyer | Det | sp | 31 | 7.92 | 2 | 12 | 0 | 24 | 24 | 1 | 1 | 100.0 | 152 | 89 | 88 | 44 | 67 | 25 | 12 |
| Randy Williams* | Mtl | mr | 34 | 5.40 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 13.1 | 10 | 10 | 8 | 11 | 16 | 0 | 0 |
| Dontrelle Willis* | Mtl | sp | 28 | 7.15 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 11.1 | 16 | 10 | 9 | 6 | 4 | 1 | 1 |
| C.J. Wilson* | KCR | mr | 29 | 3.52 | 5 | 6 | 2 | 57 | 0 | 0 | 0 | 79.1 | 65 | 34 | 31 | 46 | 79 | 2 | 9 |
| Randy Wolf* | ChW | sp | 33 | 4.36 | 14 | 10 | 0 | 34 | 34 | 1 | 0 | 218.2 | 230 | 115 | 106 | 73 | 163 | 30 | 20 |
| Kerry Wood | Det | cl | 33 | 5.06 | 1 | 9 | 13 | 43 | 0 | 0 | 0 | 53.1 | 51 | 32 | 30 | 17 | 67 | 13 | 5 |
| Tim Wood | KCR | mr | 27 | 5.40 | 1 | 0 | 1 | 13 | 0 | 0 | 0 | 25.0 | 31 | 16 | 15 | 12 | 16 | 1 | 8 |
| Michael Wuertz | Tex | mr | 31 | 2.12 | 6 | 3 | 10 | 71 | 0 | 0 | 0 | 106.1 | 69 | 28 | 25 | 31 | 142 | 1 | 1 |
| Yasuhiko Yabuta | Cle | mr | 37 | 15.75 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.0 | 14 | 7 | 7 | 1 | 4 | 1 | 0 |
| Clay Zavada* | Mtl | mr | 26 | 2.88 | 3 | 3 | 2 | 47 | 0 | 0 | 0 | 65.2 | 46 | 22 | 21 | 19 | 59 | 7 | 4 |
| Brad Ziegler | NYY | mr | 30 | 2.93 | 1 | 2 | 4 | 35 | 0 | 0 | 0 | 46.0 | 51 | 15 | 15 | 12 | 33 | 0 | 13 |
| Jordan Zimmermann | Bal | sp | 24 | 3.88 | 9 | 6 | 0 | 20 | 20 | 1 | 0 | 127.2 | 135 | 59 | 55 | 45 | 131 | 14 | 11 |
| Barry Zito* | ChW | sp | 32 | 5.22 | 16 | 11 | 0 | 32 | 32 | 1 | 0 | 194.2 | 228 | 120 | 113 | 84 | 172 | 21 | 22 |
| Joel Zumaya | NYY | mr | 25 | 5.92 | 2 | 0 | 2 | 19 | 0 | 0 | 0 | 24.1 | 24 | 17 | 16 | 18 | 17 | 5 | 3 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Jeremy Accardo | ChW | mr | 28 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 7.3 | 5.6 | 12.9 | 8.9 | 0.4 | 1.6 | 1.43 |
| Alfredo Aceves | Was | mr | 27 | 5 | 1 | 0 | 7 | 0 | 0 | 4 | 3 | 5.2 | 1.0 | 6.8 | 7.8 | 0.9 | 7.9 | 0.69 |
| Nick Adenhart | Bal | sp | 23 | 1 | 2 | 0 | 1 | 5 | 0 | 1 | 0 | 7.1 | 3.6 | 11.0 | 6.5 | 0.6 | 1.8 | 1.19 |
| Jeremy Affeldt* | NYY | mr | 31 | 3 | 0 | 0 | 2 | 4 | 0 | 2 | 3 | 6.7 | 4.3 | 11.3 | 8.1 | 0.6 | 1.9 | 1.22 |
| Matt Albers | Tex | mr | 27 | 4 | 0 | 2 | 1 | 3 | 0 | 1 | 3 | 12.3 | 4.6 | 17.0 | 7.0 | 0.6 | 1.5 | 1.88 |
| Jose Arredondo | Cle | mr | 26 | 3 | 0 | 2 | 3 | 5 | 1 | 2 | 3 | 11.9 | 5.0 | 17.9 | 10.7 | 1.3 | 2.1 | 1.88 |
| Jose Ascanio | Bal | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.6 | 2.2 | 9.7 | 13.0 | 1.1 | 6.0 | 1.08 |
| John Axford | Cle | mr | 27 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 5.6 | 5.6 | 12.4 | 4.5 | 1.1 | 0.8 | 1.25 |
| Burke Badenhop | KCR | mr | 27 | 9 | 2 | 1 | 1 | 0 | 0 | 3 | 1 | 10.5 | 2.9 | 13.4 | 7.3 | 0.5 | 2.6 | 1.48 |
| Danys Baez | Min | mr | 32 | 5 | 3 | 6 | 9 | 0 | 1 | 3 | 2 | 6.1 | 2.6 | 9.9 | 5.2 | 0.9 | 2.0 | 0.97 |
| Homer Bailey | Tor | sp | 24 | 13 | 7 | 1 | 6 | 4 | 0 | 2 | 6 | 9.6 | 3.2 | 13.3 | 6.3 | 1.1 | 2.0 | 1.43 |
| John Bale* | Sea | mr | 36 | 3 | 2 | 3 | 3 | 0 | 0 | 2 | 0 | 6.7 | 5.8 | 13.4 | 5.2 | 0.9 | 0.9 | 1.39 |
| Josh Banks | Mtl | sp | 27 | 2 | 0 | 1 | 2 | 1 | 0 | 1 | 2 | 18.0 | 0.7 | 19.4 | 2.1 | 1.7 | 3.0 | 2.08 |
| Daniel Bard | Tor | mr | 25 | 4 | 2 | 4 | 3 | 1 | 1 | 0 | 2 | 6.0 | 6.6 | 13.0 | 12.0 | 1.3 | 1.8 | 1.40 |
| Brian Bass | LAA | mr | 28 | 4 | 3 | 0 | 4 | 8 | 0 | 1 | 2 | 9.6 | 3.8 | 13.8 | 6.3 | 0.9 | 1.6 | 1.49 |
| Miguel Batista | Bal | mr | 39 | 7 | 2 | 1 | 2 | 2 | 0 | 0 | 0 | 11.1 | 5.1 | 16.4 | 7.8 | 0.7 | 1.5 | 1.80 |
| Josh Beckett | KCR | sp | 30 | 7 | 6 | 2 | 4 | 2 | 2 | 2 | 9 | 9.1 | 2.7 | 12.0 | 8.7 | 1.0 | 3.3 | 1.31 |
| Joe Beimel* |   | mr | 33 | 0 | 0 | 1 | 2 | 6 | 1 | 1 | 3 | 8.9 | 2.3 | 11.5 | 7.1 | 0.9 | 3.1 | 1.24 |
| Trevor Bell | LAA | sp | 23 | 3 | 1 | 4 | 1 | 1 | 0 | 1 | 1 | 14.8 | 5.0 | 20.0 | 5.0 | 1.1 | 1.0 | 2.20 |
| Kris Benson | Oak | mr | 35 | 2 | 0 | 0 | 5 | 1 | 0 | 2 | 3 | 11.5 | 4.4 | 17.2 | 4.7 | 2.5 | 1.1 | 1.77 |
| Brad Bergesen | Tex | sp | 24 | 2 | 1 | 3 | 9 | 0 | 0 | 1 | 4 | 8.9 | 1.9 | 11.3 | 5.0 | 1.1 | 2.6 | 1.20 |
| Jason Berken | Oak | sp | 26 | 6 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 14.4 | 2.2 | 17.0 | 5.2 | 1.8 | 2.3 | 1.85 |
| Rafael Betancourt | NYY | mr | 35 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.3 | 4.3 | 8.6 | 10.8 | 0.0 | 2.5 | 0.96 |
| Jerry Blevins* | Mtl | mr | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 7.3 | 2.4 | 9.7 | 9.1 | 0.6 | 3.8 | 1.08 |
| Mitchell Boggs | Det | sp | 26 | 8 | 0 | 11 | 5 | 5 | 4 | 1 | 4 | 13.5 | 7.3 | 21.3 | 7.4 | 0.8 | 1.0 | 2.31 |
| Blaine Boyer | ChW | mr | 28 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9.8 | 5.9 | 15.7 | 4.4 | 0.5 | 0.8 | 1.75 |
| Dallas Braden* | Mtl | sp | 26 | 3 | 4 | 7 | 6 | 1 | 0 | 5 | 5 | 11.8 | 2.6 | 14.7 | 5.2 | 0.6 | 2.0 | 1.60 |
| Doug Brocail | Det | mr | 43 | 0 | 0 | 1 | 1 | 3 | 0 | 0 | 1 | 14.7 | 8.9 | 23.9 | 6.5 | 3.4 | 0.7 | 2.62 |
| Brian Bruney | ChW | mr | 28 | 4 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 8.3 | 5.1 | 13.4 | 7.0 | 1.9 | 1.4 | 1.49 |
| Clay Buchholz | Cle | sp | 25 | 4 | 3 | 2 | 2 | 1 | 0 | 2 | 4 | 9.5 | 3.3 | 13.0 | 6.1 | 1.0 | 1.9 | 1.42 |
| Jason Bulger | KCR | mr | 31 | 7 | 3 | 1 | 3 | 4 | 0 | 0 | 2 | 7.9 | 3.8 | 12.1 | 10.0 | 0.8 | 2.7 | 1.30 |
| Madison Bumgarner* | Sea | mr | 20 | 3 | 1 | 1 | 1 | 2 | 0 | 0 | 1 | 12.1 | 4.6 | 16.9 | 6.3 | 2.6 | 1.4 | 1.85 |
| Greg Burke | Tex | mr | 27 | 0 | 1 | 3 | 3 | 4 | 0 | 3 | 4 | 11.3 | 2.2 | 14.0 | 6.7 | 0.7 | 3.0 | 1.50 |
| Tim Byrdak* | Bos | mr | 36 | 2 | 1 | 0 | 1 | 0 | 0 | 1 | 3 | 4.7 | 4.4 | 9.2 | 7.7 | 0.7 | 1.8 | 1.00 |
| Kiko Calero | ChW | mr | 35 | 3 | 2 | 0 | 2 | 0 | 0 | 2 | 5 | 4.5 | 4.4 | 9.2 | 10.5 | 0.5 | 2.4 | 1.00 |
| Kevin Cameron | Min | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.1 | 1.4 | 8.5 | 12.8 | 0.0 | 9.0 | 0.95 |
| Shawn Camp | Det | mr | 34 | 3 | 3 | 0 | 10 | 0 | 0 | 2 | 6 | 8.2 | 2.5 | 11.5 | 6.9 | 0.5 | 2.7 | 1.19 |
| Matt Capps | Sea | cl | 26 | 5 | 3 | 6 | 4 | 0 | 0 | 2 | 3 | 14.2 | 2.5 | 17.2 | 7.4 | 2.3 | 2.9 | 1.86 |
| Chris Carpenter | NYY | sp | 35 | 7 | 4 | 1 | 3 | 0 | 0 | 2 | 6 | 8.3 | 2.2 | 10.7 | 7.1 | 0.8 | 3.2 | 1.17 |
| Alberto Castillo* |   | mr | 34 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 12.0 | 5.0 | 20.0 | 3.0 | 2.0 | 0.6 | 1.89 |
| Brett Cecil* | Tor | sp | 23 | 9 | 2 | 4 | 10 | 0 | 0 | 1 | 2 | 10.0 | 3.7 | 14.5 | 8.1 | 1.0 | 2.2 | 1.52 |
| Jhoulys Chacin | Cle | mr | 22 | 2 | 2 | 2 | 0 | 4 | 0 | 1 | 0 | 8.1 | 6.3 | 14.4 | 11.1 | 0.7 | 1.8 | 1.60 |
| Bruce Chen* | Cle | sp | 33 | 2 | 2 | 1 | 1 | 3 | 0 | 1 | 4 | 9.7 | 3.9 | 13.8 | 4.2 | 2.0 | 1.1 | 1.51 |
| Randy Choate* | Min | mr | 34 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 4.4 | 2.6 | 7.0 | 7.0 | 0.2 | 2.7 | 0.78 |
| Tyler Clippard | Sea | mr | 25 | 4 | 1 | 0 | 3 | 3 | 4 | 3 | 2 | 5.3 | 5.6 | 11.3 | 11.6 | 0.9 | 2.1 | 1.21 |
| Phil Coke* | Bal | mr | 27 | 1 | 1 | 0 | 2 | 3 | 0 | 1 | 3 | 6.9 | 2.2 | 9.4 | 7.9 | 1.7 | 3.7 | 1.01 |
| Bartolo Colon | Was | sp | 37 | 4 | 1 | 0 | 3 | 1 | 0 | 2 | 4 | 10.3 | 2.8 | 13.5 | 5.3 | 2.9 | 1.9 | 1.46 |
| Roman Colon | Cle | mr | 30 | 5 | 1 | 1 | 4 | 0 | 1 | 0 | 1 | 7.3 | 3.9 | 11.8 | 6.2 | 0.9 | 1.6 | 1.24 |
| Roy Corcoran | Det | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 16.2 | 18.0 | 34.2 | 3.6 | 3.6 | 0.2 | 3.80 |
| Francisco Cordero | Tex | cl | 35 | 6 | 1 | 3 | 0 | 4 | 0 | 1 | 2 | 9.7 | 4.6 | 14.4 | 7.0 | 0.3 | 1.5 | 1.60 |
| Lance Cormier | Det | mr | 29 | 4 | 1 | 1 | 3 | 3 | 0 | 0 | 4 | 8.1 | 2.7 | 11.1 | 5.2 | 0.8 | 1.9 | 1.20 |
| Kevin Correia | Mtl | sp | 29 | 2 | 6 | 2 | 3 | 11 | 2 | 3 | 6 | 10.8 | 3.3 | 14.3 | 5.9 | 1.1 | 1.8 | 1.57 |
| Juan Cruz | Cle | mr | 31 | 1 | 1 | 1 | 2 | 6 | 0 | 2 | 3 | 6.8 | 4.6 | 11.7 | 8.4 | 0.6 | 1.8 | 1.26 |
| Johnny Cueto | Sea | sp | 24 | 6 | 5 | 1 | 13 | 0 | 0 | 3 | 4 | 10.4 | 3.6 | 14.7 | 6.8 | 1.6 | 1.9 | 1.56 |
| John Danks* | NYY | sp | 25 | 13 | 4 | 0 | 5 | 2 | 0 | 6 | 4 | 8.1 | 3.3 | 11.6 | 7.8 | 1.7 | 2.4 | 1.26 |
| Wade Davis | Min | sp | 24 | 4 | 2 | 0 | 2 | 3 | 0 | 0 | 2 | 9.9 | 3.7 | 13.9 | 9.6 | 1.1 | 2.6 | 1.51 |
| Jorge de la Rosa* | Was | sp | 29 | 17 | 7 | 5 | 8 | 8 | 1 | 0 | 1 | 8.4 | 3.7 | 12.4 | 9.6 | 0.9 | 2.6 | 1.34 |
| Manny Delcarmen | Cle | mr | 28 | 4 | 3 | 1 | 2 | 2 | 0 | 1 | 3 | 8.2 | 4.4 | 12.8 | 4.9 | 1.2 | 1.1 | 1.39 |
| Ryan Dempster | LAA | sp | 33 | 11 | 4 | 8 | 3 | 9 | 0 | 1 | 6 | 9.3 | 3.5 | 12.9 | 7.9 | 1.3 | 2.3 | 1.42 |
| R.A. Dickey | LAA | mr | 35 | 2 | 3 | 1 | 5 | 6 | 0 | 1 | 2 | 11.1 | 3.4 | 15.0 | 6.5 | 1.0 | 1.9 | 1.61 |
| Mark DiFelice | Bos | mr | 33 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 8.3 | 1.5 | 9.8 | 8.3 | 1.5 | 5.7 | 1.08 |
| Brendan Donnelly | Bos | mr | 38 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 7.3 | 1.2 | 8.5 | 11.2 | 0.9 | 9.3 | 0.94 |
| Octavio Dotel | Bal | mr | 36 | 5 | 2 | 4 | 0 | 6 | 1 | 1 | 5 | 10.5 | 5.6 | 16.1 | 11.2 | 2.0 | 2.0 | 1.79 |
| Scott Downs* | Min | mr | 34 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3 | 8.4 | 2.1 | 10.5 | 9.0 | 0.6 | 4.3 | 1.16 |
| Brian Duensing* | Bal | mr | 27 | 5 | 3 | 0 | 6 | 1 | 0 | 1 | 1 | 8.6 | 1.6 | 10.9 | 6.1 | 0.6 | 3.8 | 1.14 |
| Zach Duke* | Tor | sp | 27 | 5 | 2 | 6 | 6 | 2 | 0 | 2 | 3 | 11.7 | 2.5 | 14.4 | 4.9 | 1.5 | 2.0 | 1.57 |
| Scott Elbert* | Cle | mr | 24 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 7.9 | 1.7 | 9.6 | 7.9 | 2.8 | 4.7 | 1.06 |
| Kelvim Escobar | Mtl | sp | 34 | 1 | 1 | 0 | 5 | 0 | 0 | 0 | 0 | 11.1 | 5.2 | 18.1 | 7.4 | 1.8 | 1.4 | 1.81 |
| Dana Eveland* | LAA | sp | 26 | 3 | 2 | 0 | 0 | 4 | 0 | 0 | 4 | 12.9 | 4.8 | 17.6 | 5.5 | 1.0 | 1.1 | 1.96 |
| Scott Eyre* | Det | mr | 38 | 2 | 1 | 3 | 2 | 4 | 0 | 2 | 6 | 7.8 | 6.6 | 14.7 | 7.6 | 0.7 | 1.2 | 1.60 |
| Alfredo Figaro | NYY | sp | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9.0 | 4.0 | 13.0 | 10.0 | 2.0 | 2.5 | 1.44 |
| Doug Fister | Bos | sp | 26 | 2 | 0 | 0 | 4 | 1 | 0 | 0 | 2 | 8.6 | 3.0 | 12.4 | 4.4 | 1.5 | 1.4 | 1.29 |
| Randy Flores* | Mtl | mr | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.7 | 11.6 | 19.3 | 7.7 | 3.9 | 0.7 | 2.14 |
| Josh Fogg | Bos | mr | 33 | 0 | 1 | 2 | 1 | 3 | 0 | 2 | 1 | 5.4 | 2.7 | 8.3 | 5.6 | 1.3 | 2.1 | 0.90 |
| Ryan Franklin | LAA | cl | 37 | 6 | 1 | 0 | 4 | 4 | 1 | 4 | 2 | 7.0 | 2.9 | 10.4 | 6.0 | 0.6 | 2.0 | 1.10 |
| Lucas French* | Det | sp | 24 | 6 | 0 | 3 | 4 | 9 | 0 | 1 | 5 | 14.0 | 4.7 | 19.1 | 6.8 | 1.8 | 1.5 | 2.07 |
| Ernesto Frieri | Mtl | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 0.0 | 13.5 | 13.5 | 13.5 | 99.0 | 1.50 |
| Jaime Garcia* | Sea | mr | 23 | 3 | 0 | 1 | 2 | 10 | 0 | 0 | 1 | 11.1 | 8.1 | 19.9 | 5.1 | 3.0 | 0.6 | 2.14 |
| Matt Garza | Bal | sp | 26 | 16 | 7 | 0 | 15 | 4 | 0 | 5 | 8 | 9.1 | 3.3 | 13.1 | 8.5 | 1.3 | 2.5 | 1.38 |
| Chad Gaudin | Sea | sp | 27 | 7 | 3 | 7 | 8 | 8 | 3 | 2 | 4 | 8.5 | 4.9 | 13.8 | 8.6 | 0.7 | 1.8 | 1.49 |
| Josh Geer | Tex | sp | 27 | 3 | 1 | 0 | 2 | 0 | 0 | 2 | 2 | 13.9 | 1.0 | 15.2 | 4.0 | 3.0 | 4.0 | 1.66 |
| Edgar Gonzalez | NYY | mr | 27 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 9.8 | 4.1 | 15.5 | 3.3 | 1.6 | 0.8 | 1.55 |
| Gio Gonzalez* | Sea | sp | 24 | 3 | 1 | 0 | 4 | 3 | 0 | 0 | 3 | 9.7 | 5.3 | 15.3 | 10.0 | 1.2 | 1.9 | 1.66 |
| Mike Gonzalez* | Cle | mr | 32 | 4 | 1 | 1 | 6 | 2 | 0 | 2 | 3 | 6.1 | 3.4 | 10.3 | 9.9 | 0.7 | 2.9 | 1.06 |
| Tom Gorzelanny* | Sea | mr | 27 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 2 | 9.0 | 2.9 | 12.0 | 8.6 | 1.3 | 3.0 | 1.33 |
| Mike Gosling* | Sea | mr | 29 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 2 | 9.4 | 2.0 | 11.5 | 5.1 | 2.4 | 2.5 | 1.27 |
| Sean Green | ChW | mr | 31 | 4 | 0 | 2 | 7 | 14 | 3 | 1 | 3 | 9.0 | 4.5 | 14.2 | 6.3 | 0.9 | 1.4 | 1.49 |
| Luke Gregerson | Mtl | mr | 26 | 3 | 1 | 2 | 4 | 3 | 0 | 2 | 2 | 7.5 | 1.5 | 9.4 | 11.1 | 0.5 | 7.4 | 1.00 |
| Kevin Gregg | Sea | cl | 32 | 1 | 1 | 3 | 2 | 4 | 0 | 4 | 1 | 6.9 | 3.0 | 10.1 | 8.0 | 1.3 | 2.7 | 1.09 |
| Zack Greinke | Bos | sp | 26 | 2 | 1 | 2 | 4 | 4 | 0 | 3 | 5 | 7.1 | 1.4 | 8.6 | 10.7 | 0.4 | 7.8 | 0.94 |
| Eddie Guardado* | LAA | mr | 39 | 6 | 1 | 0 | 5 | 0 | 0 | 1 | 1 | 7.3 | 3.2 | 11.7 | 7.1 | 0.6 | 2.2 | 1.18 |
| Matt Guerrier | Was | mr | 31 | 6 | 1 | 3 | 4 | 6 | 0 | 0 | 4 | 5.3 | 1.7 | 7.4 | 7.6 | 0.7 | 4.6 | 0.78 |
| Charlie Haeger | Cle | sp | 26 | 2 | 0 | 0 | 9 | 0 | 1 | 0 | 0 | 5.4 | 2.1 | 9.2 | 8.8 | 1.5 | 4.3 | 0.83 |
| Jason Hammel | ChW | sp | 27 | 21 | 4 | 1 | 13 | 1 | 0 | 1 | 8 | 12.3 | 2.0 | 15.0 | 6.4 | 1.3 | 3.2 | 1.60 |
| Mike Hampton* | Cle | sp | 37 | 9 | 5 | 0 | 1 | 1 | 0 | 4 | 1 | 8.7 | 2.6 | 11.4 | 6.9 | 1.0 | 2.7 | 1.26 |
| Joel Hanrahan | Tex | mr | 28 | 4 | 3 | 3 | 2 | 14 | 0 | 0 | 0 | 14.2 | 5.9 | 20.5 | 11.2 | 0.7 | 1.9 | 2.24 |
| Tommy Hanson | Was | sp | 23 | 23 | 2 | 2 | 6 | 4 | 0 | 1 | 4 | 7.5 | 3.0 | 10.8 | 6.8 | 1.0 | 2.3 | 1.17 |
| J.A. Happ* | LAA | sp | 27 | 9 | 3 | 0 | 8 | 3 | 0 | 2 | 4 | 9.7 | 3.9 | 14.1 | 6.1 | 1.5 | 1.5 | 1.51 |
| Aaron Harang | Tor | sp | 32 | 17 | 2 | 1 | 7 | 7 | 0 | 2 | 2 | 10.3 | 1.9 | 12.5 | 7.1 | 1.6 | 3.7 | 1.35 |
| Kevin Hart | Bos | sp | 27 | 5 | 0 | 2 | 0 | 2 | 0 | 1 | 0 | 9.0 | 4.7 | 13.7 | 6.3 | 0.4 | 1.3 | 1.52 |
| Blake Hawksworth | ChW | mr | 27 | 1 | 0 | 3 | 1 | 1 | 0 | 2 | 1 | 5.6 | 3.8 | 9.6 | 5.3 | 0.9 | 1.4 | 1.04 |
| Aaron Heilman | Sea | mr | 31 | 7 | 3 | 0 | 3 | 2 | 0 | 2 | 4 | 7.6 | 4.7 | 12.6 | 8.0 | 0.7 | 1.7 | 1.37 |
| Matt Herges | Min | mr | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.2 | 2.1 | 6.2 | 5.2 | 1.0 | 2.5 | 0.69 |
| David Hernandez | ChW | sp | 25 | 4 | 1 | 1 | 0 | 0 | 0 | 1 | 3 | 12.5 | 4.5 | 17.0 | 6.2 | 1.5 | 1.4 | 1.89 |
| Felix Hernandez | Min | sp | 24 | 20 | 5 | 2 | 8 | 20 | 1 | 2 | 3 | 7.7 | 2.9 | 10.9 | 8.9 | 0.4 | 3.1 | 1.18 |
| Livan Hernandez | Oak | sp | 35 | 3 | 3 | 0 | 3 | 1 | 0 | 2 | 10 | 12.1 | 3.1 | 15.4 | 5.3 | 1.4 | 1.7 | 1.69 |
| Shawn Hill | Det | sp | 29 | 6 | 0 | 1 | 2 | 2 | 0 | 0 | 1 | 18.5 | 2.1 | 21.7 | 6.9 | 1.1 | 3.3 | 2.29 |
| Trevor Hoffman | ChW | cl | 42 | 2 | 1 | 2 | 0 | 0 | 0 | 3 | 4 | 6.4 | 2.2 | 8.6 | 6.7 | 1.3 | 3.0 | 0.96 |
| J.P. Howell* | Bos | mr | 27 | 7 | 1 | 2 | 7 | 4 | 2 | 3 | 1 | 6.0 | 3.0 | 9.9 | 11.0 | 0.4 | 3.7 | 1.00 |
| Tommy Hunter | KCR | sp | 23 | 8 | 3 | 1 | 2 | 9 | 1 | 1 | 7 | 9.2 | 2.3 | 11.6 | 4.9 | 1.1 | 2.2 | 1.27 |
| Edwin Jackson | Min | sp | 26 | 13 | 6 | 0 | 6 | 4 | 0 | 5 | 12 | 8.5 | 2.9 | 11.6 | 6.4 | 1.0 | 2.2 | 1.27 |
| Steven Jackson | Det | mr | 28 | 6 | 0 | 2 | 0 | 7 | 0 | 2 | 4 | 6.9 | 5.5 | 12.5 | 3.5 | 0.5 | 0.6 | 1.39 |
| Zach Jackson* | Mtl | mr | 27 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 18.0 | 3.3 | 21.3 | 11.5 | 2.5 | 3.5 | 2.36 |
| Chris Jakubauskas | Mtl | mr | 31 | 1 | 2 | 1 | 4 | 3 | 1 | 0 | 5 | 9.7 | 2.2 | 12.2 | 4.7 | 1.3 | 2.1 | 1.32 |
| Bobby Jenks | KCR | cl | 29 | 4 | 0 | 0 | 2 | 1 | 0 | 1 | 0 | 7.3 | 2.1 | 9.7 | 9.5 | 1.3 | 4.6 | 1.04 |
| Waldis Joaquin | ChW | mr | 23 | 1 | 0 | 0 | 2 | 1 | 0 | 4 | 1 | 12.4 | 7.9 | 22.5 | 7.9 | 1.1 | 1.0 | 2.25 |
| Jim Johnson | NYY | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 8.3 | 3.1 | 12.5 | 6.2 | 1.0 | 2.0 | 1.27 |
| Josh Johnson | Min | sp | 26 | 15 | 8 | 5 | 7 | 6 | 0 | 2 | 5 | 8.1 | 2.9 | 11.2 | 8.0 | 1.0 | 2.8 | 1.22 |
| Jair Jurrjens |   | sp | 24 | 11 | 8 | 3 | 4 | 1 | 2 | 2 | 13 | 10.1 | 3.5 | 13.8 | 5.9 | 0.7 | 1.7 | 1.51 |
| Scott Kazmir* | Bos | sp | 26 | 7 | 3 | 3 | 9 | 9 | 0 | 3 | 8 | 10.1 | 4.1 | 14.8 | 7.1 | 0.4 | 1.7 | 1.58 |
| Kyle Kendrick | Det | mr | 25 | 1 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 10.5 | 2.8 | 13.5 | 3.3 | 0.5 | 1.2 | 1.47 |
| Hong-Chih Kuo* | Bos | mr | 28 | 1 | 3 | 0 | 1 | 6 | 0 | 1 | 1 | 5.4 | 2.7 | 8.3 | 10.2 | 0.5 | 3.8 | 0.89 |
| John Lackey |   | sp | 31 | 19 | 4 | 8 | 9 | 1 | 0 | 5 | 3 | 9.2 | 2.3 | 11.9 | 7.3 | 1.0 | 3.2 | 1.27 |
| John Lannan* | Was | sp | 25 | 11 | 6 | 2 | 11 | 1 | 0 | 1 | 3 | 9.3 | 3.6 | 13.3 | 3.7 | 1.0 | 1.0 | 1.43 |
| Mat Latos | Bal | sp | 22 | 4 | 3 | 2 | 1 | 0 | 3 | 2 | 5 | 11.3 | 5.1 | 16.5 | 8.1 | 2.2 | 1.6 | 1.82 |
| Brandon League | Min | mr | 27 | 5 | 1 | 4 | 4 | 5 | 0 | 3 | 1 | 9.9 | 3.2 | 13.9 | 8.6 | 1.3 | 2.7 | 1.46 |
| Wade LeBlanc* | NYY | sp | 25 | 7 | 2 | 0 | 8 | 1 | 1 | 0 | 3 | 7.2 | 3.6 | 11.7 | 4.2 | 2.7 | 1.2 | 1.19 |
| Justin Lehr | Tex | sp | 32 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 17.8 | 3.7 | 21.5 | 4.9 | 2.5 | 1.3 | 2.39 |
| Jensen Lewis | Cle | mr | 26 | 2 | 1 | 5 | 1 | 3 | 2 | 1 | 2 | 9.0 | 4.6 | 13.7 | 9.6 | 2.3 | 2.1 | 1.51 |
| Matt Lindstrom | Sea | cl | 30 | 5 | 1 | 2 | 0 | 0 | 5 | 2 | 1 | 8.1 | 3.5 | 11.7 | 6.3 | 0.3 | 1.8 | 1.30 |
| Scott Linebrink | LAA | mr | 33 | 2 | 3 | 1 | 2 | 7 | 0 | 1 | 3 | 8.7 | 2.4 | 11.3 | 8.7 | 1.3 | 3.6 | 1.23 |
| Francisco Liriano* | Min | sp | 26 | 2 | 3 | 0 | 4 | 5 | 0 | 3 | 3 | 9.0 | 4.9 | 14.2 | 9.5 | 0.9 | 1.9 | 1.55 |
| Kyle Lohse |   | sp | 31 | 10 | 6 | 7 | 5 | 5 | 0 | 1 | 4 | 9.8 | 3.3 | 13.4 | 6.1 | 1.9 | 1.9 | 1.45 |
| Braden Looper | Tex | sp | 35 | 8 | 2 | 6 | 3 | 5 | 0 | 2 | 5 | 13.1 | 3.1 | 16.3 | 4.2 | 2.5 | 1.4 | 1.79 |
| Rodrigo Lopez | Sea | sp | 34 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 12.2 | 2.3 | 14.5 | 6.5 | 1.6 | 2.8 | 1.62 |
| Mark Lowe | Bos | mr | 27 | 7 | 2 | 5 | 2 | 5 | 0 | 2 | 3 | 9.1 | 4.9 | 14.3 | 8.7 | 0.8 | 1.8 | 1.56 |
| Paul Maholm* | NYY | sp | 28 | 5 | 2 | 3 | 2 | 9 | 2 | 1 | 2 | 11.7 | 3.0 | 14.9 | 6.1 | 1.4 | 2.0 | 1.64 |
| Robert Manuel | Cle | mr | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.7 | 0.0 | 7.1 | 11.4 | 0.0 | 99.0 | 0.63 |
| Carlos Marmol | Bal | mr | 27 | 2 | 2 | 0 | 3 | 2 | 0 | 4 | 0 | 5.4 | 6.2 | 12.1 | 12.6 | 0.2 | 2.0 | 1.29 |
| Jason Marquis | Was | sp | 31 | 27 | 6 | 5 | 5 | 6 | 0 | 1 | 4 | 9.0 | 3.5 | 12.7 | 4.0 | 0.8 | 1.1 | 1.39 |
| Pedro Martinez | Was | sp | 38 | 7 | 1 | 0 | 10 | 1 | 0 | 1 | 1 | 10.6 | 2.4 | 14.4 | 8.8 | 1.3 | 3.7 | 1.45 |
| Shairon Martis | KCR | sp | 23 | 4 | 3 | 2 | 4 | 2 | 0 | 1 | 2 | 7.6 | 5.1 | 13.1 | 4.4 | 0.5 | 0.9 | 1.40 |
| Justin Masterson | NYY | mr | 25 | 4 | 0 | 1 | 3 | 2 | 0 | 1 | 0 | 10.7 | 2.6 | 13.8 | 8.4 | 1.3 | 3.2 | 1.48 |
| Brian Matusz* | Tex | sp | 23 | 5 | 4 | 1 | 1 | 0 | 0 | 0 | 2 | 9.7 | 2.6 | 12.4 | 7.5 | 1.6 | 2.9 | 1.36 |
| Brandon McCarthy | NYY | sp | 26 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 3 | 7.7 | 2.5 | 10.6 | 6.5 | 1.3 | 2.6 | 1.14 |
| Kyle McClellan | Bal | mr | 26 | 2 | 1 | 0 | 2 | 5 | 0 | 2 | 7 | 7.6 | 5.3 | 13.1 | 7.3 | 1.1 | 1.4 | 1.43 |
| Seth McClung | Tor | mr | 29 | 1 | 2 | 5 | 3 | 2 | 0 | 2 | 1 | 9.9 | 5.9 | 16.2 | 5.4 | 1.6 | 0.9 | 1.76 |
| Gil Meche | KCR | sp | 31 | 14 | 8 | 0 | 9 | 5 | 0 | 2 | 4 | 8.0 | 3.8 | 12.4 | 6.9 | 1.0 | 1.8 | 1.32 |
| Cla Meredith | LAA | mr | 27 | 7 | 4 | 2 | 3 | 4 | 0 | 2 | 1 | 12.7 | 2.1 | 15.1 | 5.3 | 1.7 | 2.6 | 1.64 |
| Randy Messenger | Det | mr | 28 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 18.0 | 0.8 | 18.8 | 6.8 | 2.3 | 9.0 | 2.08 |
| Dan Meyer* | NYY | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.8 | 2.9 | 8.8 | 9.5 | 0.7 | 3.3 | 0.97 |
| Kam Mickolio | ChW | mr | 26 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 5.5 | 4.5 | 10.0 | 7.5 | 0.0 | 1.7 | 1.11 |
| Andrew Miller* | LAA | sp | 25 | 9 | 2 | 2 | 5 | 12 | 0 | 2 | 5 | 10.3 | 5.2 | 16.0 | 6.6 | 0.5 | 1.3 | 1.73 |
| Trever Miller* | Was | mr | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.3 | 1.0 | 8.3 | 8.3 | 1.0 | 8.0 | 0.92 |
| Kevin Millwood |   | sp | 35 | 19 | 10 | 3 | 7 | 4 | 0 | 3 | 7 | 9.5 | 3.6 | 13.4 | 5.3 | 1.4 | 1.5 | 1.45 |
| Eric Milton* | Sea | sp | 34 | 3 | 0 | 0 | 5 | 0 | 0 | 3 | 1 | 9.9 | 2.0 | 12.6 | 7.1 | 0.7 | 3.6 | 1.32 |
| Zach Miner | Det | mr | 28 | 1 | 2 | 0 | 4 | 2 | 0 | 0 | 4 | 11.8 | 6.4 | 18.7 | 6.2 | 1.2 | 1.0 | 2.03 |
| Brandon Morrow | NYY | cl | 25 | 9 | 3 | 1 | 3 | 0 | 0 | 0 | 3 | 8.1 | 5.6 | 14.1 | 9.2 | 1.0 | 1.6 | 1.52 |
| Clayton Mortensen | Mtl | sp | 25 | 1 | 1 | 3 | 6 | 1 | 0 | 0 | 4 | 9.7 | 5.5 | 16.2 | 3.1 | 1.1 | 0.6 | 1.68 |
| Charlie Morton | Det | sp | 26 | 7 | 1 | 3 | 2 | 5 | 0 | 1 | 3 | 12.8 | 4.6 | 17.6 | 6.5 | 1.3 | 1.4 | 1.94 |
| Guillermo Mota | NYY | mr | 36 | 2 | 2 | 0 | 5 | 0 | 0 | 1 | 0 | 8.3 | 2.2 | 11.3 | 5.6 | 1.0 | 2.5 | 1.16 |
| Jason Motte | Was | mr | 28 | 5 | 0 | 3 | 0 | 0 | 3 | 1 | 0 | 12.5 | 2.8 | 15.3 | 6.5 | 1.9 | 2.3 | 1.70 |
| Jamie Moyer* | NYY | sp | 47 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 10.8 | 2.7 | 15.3 | 3.6 | 0.0 | 1.3 | 1.50 |
| Edward Mujica | Min | mr | 26 | 1 | 0 | 0 | 0 | 1 | 2 | 1 | 2 | 9.9 | 1.8 | 11.7 | 7.9 | 2.1 | 4.3 | 1.31 |
| Brett Myers | Oak | sp | 29 | 11 | 5 | 0 | 6 | 0 | 0 | 1 | 2 | 8.7 | 3.5 | 12.8 | 6.6 | 2.1 | 1.9 | 1.36 |
| Chris Narveson* | KCR | mr | 28 | 1 | 1 | 2 | 2 | 7 | 0 | 2 | 4 | 12.1 | 5.0 | 17.4 | 9.0 | 1.3 | 1.8 | 1.90 |
| Joe Nelson | Bos | mr | 35 | 5 | 2 | 1 | 0 | 1 | 2 | 1 | 4 | 10.5 | 6.4 | 16.9 | 8.8 | 1.1 | 1.4 | 1.88 |
| Fu-Te Ni* | Bal | mr | 27 | 4 | 0 | 2 | 1 | 2 | 0 | 1 | 1 | 7.2 | 2.7 | 10.2 | 4.8 | 1.5 | 1.8 | 1.10 |
| Jonathon Niese* | ChW | sp | 23 | 4 | 2 | 2 | 0 | 3 | 0 | 1 | 2 | 10.5 | 4.8 | 15.2 | 8.1 | 1.5 | 1.7 | 1.69 |
| Fernando Nieve | LAA | sp | 27 | 8 | 2 | 0 | 1 | 6 | 0 | 0 | 4 | 13.7 | 4.5 | 18.3 | 6.4 | 1.6 | 1.4 | 2.02 |
| Dustin Nippert | ChW | sp | 29 | 4 | 2 | 2 | 6 | 4 | 0 | 0 | 4 | 7.5 | 3.0 | 11.2 | 6.1 | 0.8 | 2.0 | 1.17 |
| Bud Norris | Tor | sp | 25 | 5 | 2 | 2 | 3 | 3 | 0 | 0 | 0 | 8.9 | 5.0 | 14.4 | 9.1 | 1.7 | 1.8 | 1.55 |
| Hideki Okajima* | Was | mr | 34 | 1 | 1 | 1 | 2 | 0 | 0 | 1 | 2 | 6.0 | 2.8 | 9.0 | 8.6 | 0.6 | 3.1 | 0.97 |
| Garrett Olson* | LAA | mr | 26 | 1 | 1 | 0 | 3 | 2 | 0 | 2 | 5 | 6.0 | 3.9 | 10.5 | 4.6 | 0.9 | 1.2 | 1.11 |
| Russ Ortiz | Sea | sp | 36 | 9 | 1 | 0 | 7 | 2 | 0 | 1 | 2 | 12.3 | 3.6 | 16.6 | 6.4 | 1.1 | 1.8 | 1.76 |
| Vicente Padilla | KCR | sp | 32 | 7 | 6 | 2 | 12 | 3 | 3 | 4 | 3 | 9.1 | 2.7 | 12.4 | 6.6 | 0.8 | 2.4 | 1.32 |
| Jonathan Papelbon | Min | cl | 29 | 2 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 6.3 | 2.5 | 9.1 | 10.0 | 0.5 | 3.9 | 0.98 |
| Chan Ho Park | NYY | mr | 37 | 2 | 2 | 3 | 6 | 4 | 0 | 3 | 3 | 7.6 | 3.3 | 11.6 | 8.8 | 1.2 | 2.7 | 1.21 |
| Carl Pavano | Bal | sp | 34 | 21 | 4 | 1 | 8 | 5 | 0 | 6 | 9 | 11.9 | 2.2 | 14.4 | 6.1 | 1.3 | 2.7 | 1.57 |
| Jake Peavy | Oak | sp | 29 | 14 | 3 | 2 | 3 | 3 | 1 | 2 | 5 | 8.6 | 3.4 | 12.2 | 9.5 | 1.5 | 2.8 | 1.33 |
| Tony Pena | Oak | mr | 28 | 3 | 0 | 5 | 1 | 3 | 0 | 3 | 2 | 9.7 | 2.6 | 12.3 | 6.2 | 0.6 | 2.4 | 1.36 |
| Hayden Penn | Oak | mr | 25 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 1 | 19.3 | 9.0 | 30.9 | 9.0 | 2.6 | 1.0 | 3.14 |
| Chris Perez | Mtl | mr | 24 | 4 | 1 | 1 | 8 | 9 | 0 | 1 | 2 | 9.2 | 4.0 | 14.4 | 11.2 | 2.5 | 2.8 | 1.47 |
| Oliver Perez* | LAA | sp | 28 | 8 | 4 | 2 | 7 | 2 | 0 | 2 | 3 | 9.2 | 8.6 | 18.4 | 9.4 | 1.9 | 1.1 | 1.97 |
| Glen Perkins* | Oak | sp | 27 | 7 | 3 | 1 | 4 | 4 | 3 | 1 | 6 | 13.8 | 1.9 | 16.0 | 4.4 | 1.1 | 2.3 | 1.74 |
| Joel Pineiro | Bos | sp | 31 | 0 | 5 | 0 | 2 | 1 | 0 | 0 | 1 | 9.6 | 0.4 | 10.3 | 3.1 | 0.3 | 7.0 | 1.11 |
| Rick Porcello | ChW | sp | 21 | 10 | 6 | 0 | 6 | 8 | 2 | 2 | 7 | 10.1 | 1.9 | 12.2 | 5.8 | 1.2 | 3.0 | 1.33 |
| David Purcey* | ChW | sp | 28 | 5 | 2 | 1 | 2 | 4 | 0 | 2 | 4 | 10.8 | 5.9 | 16.8 | 7.1 | 1.5 | 1.2 | 1.85 |
| Horacio Ramirez* | Sea | mr | 30 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 15.1 | 7.1 | 23.0 | 2.4 | 3.2 | 0.3 | 2.47 |
| Ramon Ramirez | Oak | mr | 28 | 4 | 1 | 2 | 5 | 0 | 6 | 1 | 2 | 8.4 | 3.1 | 12.2 | 7.7 | 1.0 | 2.5 | 1.28 |
| Ramon Ramirez | Mtl | mr | 27 | 1 | 2 | 0 | 6 | 1 | 0 | 0 | 0 | 17.6 | 4.1 | 25.2 | 9.4 | 7.0 | 2.3 | 2.41 |
| Chris Ray | Mtl | mr | 28 | 3 | 0 | 5 | 0 | 0 | 0 | 2 | 3 | 12.9 | 3.2 | 16.2 | 7.6 | 2.3 | 2.4 | 1.80 |
| Robert Ray | Bal | sp | 26 | 7 | 0 | 0 | 8 | 3 | 0 | 1 | 0 | 7.2 | 2.2 | 11.4 | 5.7 | 1.2 | 2.6 | 1.05 |
| Tim Redding | Bos | sp | 32 | 5 | 2 | 2 | 4 | 2 | 0 | 2 | 3 | 9.4 | 3.1 | 12.9 | 5.8 | 1.2 | 1.9 | 1.38 |
| Chad Reineke | Mtl | sp | 28 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 0 | 16.2 | 6.9 | 27.8 | 6.9 | 2.3 | 1.0 | 2.57 |
| Dennys Reyes* | Oak | mr | 33 | 4 | 1 | 1 | 6 | 9 | 0 | 4 | 2 | 9.1 | 4.5 | 14.4 | 7.9 | 0.7 | 1.8 | 1.51 |
| Arthur Rhodes* | Tor | mr | 40 | 2 | 1 | 3 | 1 | 1 | 0 | 0 | 5 | 7.9 | 5.2 | 13.2 | 9.3 | 0.3 | 1.8 | 1.45 |
| Clayton Richard* | Tex | sp | 26 | 13 | 2 | 7 | 1 | 5 | 4 | 4 | 3 | 9.4 | 5.8 | 15.3 | 7.5 | 1.4 | 1.3 | 1.69 |
| Scott Richmond | Min | sp | 30 | 0 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 7.9 | 3.4 | 11.5 | 9.5 | 1.2 | 2.8 | 1.25 |
| Juan Rincon | NYY | mr | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.5 | 4.5 | 12.0 | 7.5 | 1.5 | 1.7 | 1.33 |
| Mariano Rivera | LAA | cl | 40 | 5 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 6.1 | 1.3 | 7.8 | 10.0 | 0.5 | 7.5 | 0.82 |
| Nate Robertson* | Bos | mr | 32 | 6 | 1 | 0 | 3 | 0 | 0 | 4 | 4 | 9.3 | 3.8 | 13.4 | 6.1 | 0.5 | 1.6 | 1.46 |
| Francisco Rodriguez | Tor | cl | 28 | 2 | 0 | 2 | 2 | 1 | 0 | 2 | 3 | 4.2 | 3.3 | 7.8 | 8.8 | 0.8 | 2.6 | 0.84 |
| Henry Rodriguez | LAA | mr | 23 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 16.2 | 8.1 | 27.0 | 8.1 | 0.0 | 1.0 | 2.70 |
| Rafael Rodriguez | Tor | mr | 25 | 2 | 0 | 4 | 1 | 1 | 0 | 1 | 0 | 11.5 | 3.3 | 15.1 | 3.3 | 1.6 | 1.0 | 1.64 |
| Esmil Rogers | KCR | sp | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.8 | 4.5 | 14.3 | 4.5 | 1.5 | 1.0 | 1.58 |
| Ricky Romero* | Cle | sp | 25 | 5 | 3 | 3 | 6 | 4 | 0 | 3 | 5 | 10.7 | 4.1 | 15.1 | 6.9 | 0.7 | 1.7 | 1.64 |
| Sergio Romo | Min | mr | 27 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 3 | 9.3 | 5.6 | 15.3 | 14.1 | 0.8 | 2.5 | 1.66 |
| Carlos Rosa | ChW | mr | 25 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.5 | 3.9 | 12.3 | 6.9 | 2.3 | 1.8 | 1.37 |
| Leo Rosales | Tor | mr | 29 | 0 | 1 | 3 | 2 | 4 | 0 | 2 | 3 | 6.9 | 2.9 | 10.1 | 6.8 | 1.0 | 2.4 | 1.09 |
| Ryan Rowland-Smith* | Det | sp | 27 | 2 | 1 | 2 | 3 | 0 | 1 | 4 | 4 | 10.0 | 3.2 | 13.5 | 5.0 | 1.2 | 1.6 | 1.46 |
| B.J. Ryan* | Tor | mr | 34 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 14.7 | 8.5 | 23.9 | 6.9 | 1.5 | 0.8 | 2.57 |
| Marc Rzepczynski* | Det | sp | 24 | 4 | 6 | 0 | 2 | 4 | 0 | 1 | 1 | 7.7 | 4.1 | 12.0 | 6.8 | 1.2 | 1.7 | 1.31 |
| C.C. Sabathia* | Oak | sp | 29 | 17 | 6 | 4 | 6 | 2 | 0 | 4 | 12 | 7.9 | 2.3 | 10.4 | 7.6 | 0.5 | 3.2 | 1.13 |
| Brian Sanches | Det | mr | 31 | 4 | 3 | 3 | 11 | 7 | 0 | 1 | 2 | 7.9 | 2.7 | 11.7 | 7.5 | 1.0 | 2.8 | 1.17 |
| Ervin Santana |   | sp | 27 | 22 | 4 | 3 | 7 | 3 | 0 | 3 | 3 | 9.9 | 3.4 | 13.7 | 5.8 | 1.7 | 1.7 | 1.48 |
| Johan Santana* | Sea | sp | 31 | 7 | 1 | 2 | 9 | 1 | 0 | 1 | 8 | 8.0 | 2.3 | 10.7 | 8.5 | 1.1 | 3.7 | 1.15 |
| Dennis Sarfate | NYY | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 18.0 | 4.5 | 22.5 | 4.5 | 0.0 | 1.0 | 2.50 |
| Joe Saunders* | LAA | sp | 29 | 12 | 5 | 7 | 6 | 5 | 0 | 3 | 5 | 9.5 | 3.0 | 12.8 | 5.1 | 1.4 | 1.7 | 1.39 |
| Max Scherzer | Tor | sp | 25 | 10 | 3 | 0 | 10 | 5 | 0 | 2 | 6 | 10.0 | 3.8 | 14.3 | 9.6 | 1.2 | 2.5 | 1.54 |
| Daniel Schlereth* | Det | mr | 24 | 2 | 0 | 0 | 0 | 11 | 0 | 1 | 2 | 8.3 | 7.3 | 15.6 | 13.2 | 0.8 | 1.8 | 1.73 |
| George Sherrill* | KCR | cl | 33 | 6 | 1 | 5 | 2 | 1 | 0 | 2 | 2 | 7.3 | 2.5 | 10.0 | 9.0 | 0.4 | 3.5 | 1.09 |
| Brian Shouse* | Bal | mr | 41 | 0 | 1 | 2 | 2 | 1 | 1 | 0 | 1 | 14.2 | 3.4 | 18.9 | 5.4 | 2.7 | 1.6 | 1.95 |
| Tony Sipp* | Cle | mr | 26 | 2 | 1 | 0 | 2 | 2 | 0 | 0 | 2 | 4.3 | 5.1 | 9.7 | 9.3 | 0.8 | 1.8 | 1.04 |
| Doug Slaten* | Tex | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 8.3 | 2.1 | 10.4 | 4.2 | 0.0 | 2.0 | 1.15 |
| Kevin Slowey | Tor | sp | 26 | 7 | 4 | 5 | 11 | 5 | 0 | 1 | 4 | 11.3 | 2.3 | 14.5 | 9.3 | 1.6 | 4.0 | 1.51 |
| Joe Smith | Tor | mr | 26 | 4 | 0 | 2 | 1 | 1 | 0 | 1 | 3 | 9.1 | 5.0 | 14.4 | 10.5 | 1.3 | 2.1 | 1.57 |
| John Smoltz | Mtl | sp | 43 | 3 | 1 | 9 | 6 | 0 | 0 | 3 | 4 | 11.2 | 2.7 | 14.3 | 8.1 | 1.2 | 3.1 | 1.54 |
| Ian Snell | Tex | sp | 28 | 17 | 5 | 3 | 3 | 9 | 0 | 3 | 4 | 10.3 | 3.7 | 14.2 | 5.9 | 0.9 | 1.6 | 1.56 |
| Rafael Soriano | NYY | cl | 30 | 8 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 6.0 | 3.4 | 9.6 | 12.5 | 0.6 | 3.7 | 1.05 |
| Jorge Sosa | Det | mr | 33 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 16.6 | 8.3 | 27.0 | 6.2 | 4.2 | 0.8 | 2.77 |
| Justin Speier | Mtl | mr | 36 | 1 | 0 | 0 | 3 | 5 | 0 | 1 | 0 | 11.9 | 2.7 | 15.3 | 9.0 | 2.7 | 3.3 | 1.63 |
| Russ Springer | Tor | mr | 41 | 5 | 0 | 4 | 2 | 0 | 0 | 1 | 8 | 11.7 | 2.4 | 14.3 | 9.1 | 1.6 | 3.8 | 1.57 |
| Craig Stammen | Tex | sp | 26 | 4 | 1 | 1 | 5 | 6 | 0 | 1 | 5 | 8.2 | 1.9 | 10.4 | 4.5 | 1.4 | 2.4 | 1.12 |
| Mitch Stetter* | Was | mr | 29 | 0 | 0 | 0 | 2 | 1 | 0 | 1 | 1 | 8.2 | 4.1 | 13.1 | 6.5 | 0.4 | 1.6 | 1.36 |
| Jeff Stevens | Cle | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 3.4 | 10.1 | 6.8 | 0.0 | 2.0 | 1.13 |
| Brian Stokes | Was | mr | 30 | 3 | 3 | 2 | 3 | 0 | 0 | 0 | 1 | 8.4 | 3.9 | 12.8 | 4.9 | 0.7 | 1.3 | 1.37 |
| Jeff Suppan | Bal | sp | 35 | 2 | 5 | 1 | 11 | 10 | 0 | 0 | 6 | 12.6 | 4.3 | 17.6 | 3.6 | 1.4 | 0.8 | 1.88 |
| Ken Takahashi* | Oak | mr | 41 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | 2 | 8.0 | 4.4 | 12.8 | 9.5 | 0.4 | 2.2 | 1.38 |
| Brian Tallet* | Oak | sp | 32 | 11 | 3 | 0 | 7 | 2 | 0 | 4 | 9 | 9.7 | 3.8 | 13.8 | 7.6 | 1.1 | 2.0 | 1.50 |
| Julian Tavarez | Oak | mr | 37 | 7 | 1 | 4 | 1 | 6 | 0 | 2 | 4 | 7.5 | 6.2 | 13.8 | 6.6 | 0.3 | 1.1 | 1.52 |
| Dale Thayer | Mtl | mr | 29 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 14.7 | 0.8 | 15.4 | 3.9 | 2.3 | 5.0 | 1.71 |
| Rich Thompson | Mtl | mr | 25 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 15.3 | 2.0 | 17.6 | 9.1 | 2.3 | 4.7 | 1.92 |
| Brett Tomko | Cle | mr | 37 | 2 | 0 | 0 | 2 | 3 | 0 | 0 | 1 | 9.1 | 2.3 | 11.7 | 4.8 | 2.0 | 2.1 | 1.26 |
| Ramon Troncoso | Tex | mr | 27 | 7 | 3 | 2 | 4 | 2 | 0 | 1 | 2 | 8.2 | 3.0 | 11.5 | 5.4 | 0.5 | 1.8 | 1.24 |
| Jose Valverde | KCR | cl | 30 | 2 | 4 | 2 | 1 | 1 | 1 | 1 | 3 | 5.5 | 4.7 | 10.3 | 8.7 | 0.4 | 1.9 | 1.13 |
| Jason Vargas* | Bal | sp | 27 | 2 | 1 | 1 | 2 | 0 | 0 | 3 | 2 | 13.1 | 2.2 | 15.5 | 6.1 | 1.7 | 2.8 | 1.70 |
| Donald Veal* | LAA | mr | 25 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 8.7 | 9.6 | 18.3 | 7.7 | 1.9 | 0.8 | 2.04 |
| Justin Verlander | Cle | sp | 27 | 5 | 3 | 1 | 6 | 9 | 2 | 1 | 10 | 9.1 | 2.0 | 11.4 | 10.5 | 0.8 | 5.2 | 1.24 |
| Ron Villone* | Tex | mr | 40 | 3 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 8.0 | 4.4 | 12.8 | 7.5 | 0.7 | 1.7 | 1.38 |
| Luis Vizcaino | ChW | mr | 35 | 2 | 1 | 1 | 0 | 0 | 0 | 2 | 2 | 4.5 | 4.5 | 9.0 | 5.0 | 0.5 | 1.1 | 1.00 |
| Edinson Volquez | Mtl | sp | 26 | 4 | 1 | 1 | 9 | 3 | 2 | 1 | 4 | 9.5 | 5.7 | 16.3 | 7.6 | 1.1 | 1.3 | 1.69 |
| Chris Volstad | KCR | sp | 23 | 14 | 9 | 2 | 3 | 4 | 0 | 2 | 4 | 10.8 | 3.3 | 14.3 | 6.1 | 1.8 | 1.9 | 1.57 |
| Billy Wagner* | Tor | mr | 38 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 10.7 | 5.7 | 17.1 | 17.8 | 0.0 | 3.1 | 1.82 |
| Tim Wakefield | Min | sp | 43 | 15 | 6 | 1 | 10 | 6 | 0 | 2 | 9 | 9.1 | 3.9 | 13.5 | 5.0 | 1.0 | 1.3 | 1.43 |
| Tyler Walker | Min | mr | 34 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 7.2 | 2.2 | 9.9 | 8.3 | 0.6 | 3.8 | 1.04 |
| Jarrod Washburn* | Bos | sp | 35 | 2 | 1 | 3 | 8 | 0 | 0 | 2 | 3 | 9.5 | 2.3 | 12.2 | 5.1 | 1.0 | 2.2 | 1.31 |
| David Weathers | Oak | mr | 40 | 2 | 0 | 0 | 4 | 1 | 0 | 3 | 3 | 8.1 | 4.6 | 13.2 | 5.7 | 2.0 | 1.2 | 1.42 |
| Jeff Weaver | Was | mr | 33 | 8 | 1 | 0 | 4 | 2 | 0 | 1 | 2 | 6.8 | 1.9 | 9.2 | 7.4 | 0.6 | 3.9 | 0.96 |
| Brandon Webb | NYY | sp | 31 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 20.3 | 6.8 | 33.8 | 6.8 | 6.8 | 1.0 | 3.00 |
| Ryan Webb | Was | mr | 24 | 0 | 0 | 1 | 2 | 2 | 0 | 0 | 1 | 10.6 | 4.9 | 17.2 | 4.9 | 1.6 | 1.0 | 1.73 |
| Todd Wellemeyer | Det | sp | 31 | 4 | 3 | 2 | 3 | 4 | 0 | 1 | 4 | 13.7 | 4.0 | 17.9 | 6.0 | 2.3 | 1.5 | 1.96 |
| Randy Williams* | Mtl | mr | 34 | 0 | 0 | 3 | 3 | 1 | 0 | 0 | 1 | 6.8 | 7.4 | 16.2 | 10.8 | 0.0 | 1.5 | 1.57 |
| Dontrelle Willis* | Mtl | sp | 28 | 4 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | 12.7 | 4.8 | 17.5 | 3.2 | 0.8 | 0.7 | 1.94 |
| C.J. Wilson* | KCR | mr | 29 | 4 | 3 | 2 | 5 | 7 | 0 | 2 | 5 | 7.4 | 5.2 | 13.2 | 9.0 | 0.2 | 1.7 | 1.40 |
| Randy Wolf* | ChW | sp | 33 | 9 | 6 | 6 | 9 | 1 | 0 | 9 | 9 | 9.5 | 3.0 | 12.8 | 6.7 | 1.2 | 2.2 | 1.39 |
| Kerry Wood | Det | cl | 33 | 0 | 1 | 0 | 3 | 7 | 0 | 1 | 1 | 8.6 | 2.9 | 12.0 | 11.3 | 2.2 | 3.9 | 1.27 |
| Tim Wood | KCR | mr | 27 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 11.2 | 4.3 | 15.5 | 5.8 | 0.4 | 1.3 | 1.72 |
| Michael Wuertz | Tex | mr | 31 | 7 | 1 | 3 | 1 | 1 | 0 | 5 | 6 | 5.8 | 2.6 | 8.5 | 12.0 | 0.1 | 4.6 | 0.94 |
| Yasuhiko Yabuta | Cle | mr | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 31.5 | 2.3 | 33.8 | 9.0 | 2.3 | 4.0 | 3.75 |
| Clay Zavada* | Mtl | mr | 26 | 1 | 1 | 2 | 1 | 1 | 0 | 0 | 1 | 6.3 | 2.6 | 9.0 | 8.1 | 1.0 | 3.1 | 0.99 |
| Brad Ziegler | NYY | mr | 30 | 3 | 2 | 2 | 2 | 0 | 0 | 2 | 1 | 10.0 | 2.3 | 12.7 | 6.5 | 0.0 | 2.8 | 1.37 |
| Jordan Zimmermann | Bal | sp | 24 | 15 | 7 | 2 | 7 | 0 | 0 | 1 | 1 | 9.5 | 3.2 | 13.2 | 9.2 | 1.0 | 2.9 | 1.41 |
| Barry Zito* | ChW | sp | 32 | 1 | 6 | 3 | 6 | 5 | 0 | 1 | 5 | 10.5 | 3.9 | 14.7 | 8.0 | 1.0 | 2.0 | 1.60 |
| Joel Zumaya | NYY | mr | 25 | 3 | 0 | 2 | 1 | 1 | 0 | 1 | 0 | 8.9 | 6.7 | 15.9 | 6.3 | 1.8 | 0.9 | 1.73 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | BABIP | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Jeremy Accardo | ChW | mr | 28 | .638 | 64 | .266 | 41 | .406 | 41 | .406 | 10.1 | 4.0 | 3.67 | 3.25 |
| Alfredo Aceves | Was | mr | 27 | .470 | 267 | .180 | 107 | .280 | 114 | .298 | 19.0 | 1.6 | 1.53 | 1.32 |
| Nick Adenhart | Bal | sp | 23 | .592 | 87 | .253 | 44 | .355 | 45 | .363 | 9.1 | 2.6 | 2.43 | 2.89 |
| Jeremy Affeldt* | NYY | mr | 31 | .627 | 151 | .258 | 92 | .388 | 94 | .397 | 20.2 | 3.1 | 2.82 | 3.01 |
| Matt Albers | Tex | mr | 27 | .848 | 257 | .389 | 181 | .500 | 182 | .503 | 58.2 | 6.9 | 6.15 | 6.53 |
| Jose Arredondo | Cle | mr | 26 | .866 | 86 | .395 | 71 | .497 | 74 | .517 | 25.3 | 8.0 | 7.16 | 7.17 |
| Jose Ascanio | Bal | mr | 25 | .651 | 20 | .300 | 15 | .429 | 15 | .429 | 3.5 | 3.6 | 3.38 | 2.60 |
| John Axford | Cle | mr | 27 | .625 | 24 | .167 | 14 | .400 | 15 | .429 | 3.5 | 3.9 | 3.53 | 3.47 |
| Burke Badenhop | KCR | mr | 27 | .747 | 225 | .356 | 136 | .436 | 137 | .439 | 37.9 | 4.7 | 4.24 | 4.46 |
| Danys Baez | Min | mr | 32 | .575 | 206 | .194 | 95 | .337 | 104 | .369 | 21.4 | 2.7 | 2.50 | 2.33 |
| Homer Bailey | Tor | sp | 24 | .747 | 404 | .300 | 252 | .449 | 258 | .460 | 71.4 | 5.0 | 4.53 | 4.57 |
| John Bale* | Sea | mr | 36 | .715 | 90 | .222 | 60 | .448 | 63 | .470 | 14.3 | 4.1 | 3.73 | 3.85 |
| Josh Banks | Mtl | sp | 27 | 1.113 | 120 | .392 | 91 | .674 | 93 | .689 | 38.3 | 13.1 | 11.94 | 9.78 |
| Daniel Bard | Tor | mr | 25 | .686 | 127 | .244 | 120 | .456 | 123 | .468 | 27.8 | 4.1 | 3.75 | 3.94 |
| Brian Bass | LAA | mr | 28 | .745 | 326 | .313 | 205 | .447 | 209 | .455 | 55.7 | 4.8 | 4.28 | 4.74 |
| Miguel Batista | Bal | mr | 39 | .796 | 260 | .369 | 184 | .475 | 186 | .481 | 55.0 | 6.0 | 5.37 | 6.02 |
| Josh Beckett | KCR | sp | 30 | .747 | 604 | .321 | 418 | .464 | 422 | .468 | 109.6 | 4.6 | 4.15 | 3.89 |
| Joe Beimel* |   | mr | 33 | .712 | 155 | .290 | 93 | .433 | 95 | .442 | 25.1 | 4.5 | 4.02 | 3.52 |
| Trevor Bell | LAA | sp | 23 | .971 | 120 | .408 | 91 | .565 | 92 | .571 | 31.6 | 8.8 | 7.92 | 9.07 |
| Kris Benson | Oak | mr | 35 | .998 | 126 | .294 | 108 | .607 | 113 | .635 | 38.1 | 9.3 | 8.41 | 8.11 |
| Brad Bergesen | Tex | sp | 24 | .715 | 530 | .270 | 297 | .434 | 306 | .447 | 73.8 | 4.0 | 3.62 | 3.62 |
| Jason Berken | Oak | sp | 26 | .975 | 91 | .374 | 70 | .598 | 71 | .607 | 24.2 | 8.6 | 8.04 | 8.12 |
| Rafael Betancourt | NYY | mr | 35 | .439 | 38 | .211 | 19 | .288 | 19 | .288 | 3.0 | 1.6 | 1.47 | 1.26 |
| Jerry Blevins* | Mtl | mr | 26 | .616 | 78 | .282 | 45 | .381 | 45 | .381 | 9.8 | 3.0 | 2.67 | 2.37 |
| Mitchell Boggs | Det | sp | 26 | 1.015 | 286 | .409 | 266 | .614 | 271 | .626 | 94.9 | 10.4 | 9.30 | 8.79 |
| Blaine Boyer | ChW | mr | 28 | .752 | 61 | .311 | 38 | .458 | 38 | .458 | 11.3 | 5.8 | 4.98 | 5.40 |
| Dallas Braden* | Mtl | sp | 26 | .813 | 599 | .356 | 360 | .471 | 366 | .479 | 110.2 | 5.8 | 5.23 | 5.29 |
| Doug Brocail | Det | mr | 43 | 1.156 | 92 | .359 | 108 | .730 | 109 | .736 | 40.4 | 13.5 | 12.43 | 13.51 |
| Brian Bruney | ChW | mr | 28 | .836 | 96 | .250 | 82 | .554 | 82 | .554 | 22.6 | 6.0 | 5.43 | 5.07 |
| Clay Buchholz | Cle | sp | 25 | .751 | 398 | .302 | 251 | .460 | 253 | .463 | 66.3 | 4.7 | 4.25 | 4.42 |
| Jason Bulger | KCR | mr | 31 | .737 | 179 | .318 | 139 | .466 | 142 | .477 | 34.4 | 4.3 | 3.89 | 3.60 |
| Madison Bumgarner* | Sea | mr | 20 | 1.022 | 99 | .333 | 96 | .653 | 97 | .660 | 31.1 | 8.9 | 8.04 | 8.42 |
| Greg Burke | Tex | mr | 27 | .793 | 177 | .350 | 107 | .453 | 110 | .466 | 33.8 | 5.8 | 5.20 | 4.83 |
| Tim Byrdak* | Bos | mr | 36 | .548 | 168 | .179 | 98 | .370 | 99 | .374 | 18.9 | 2.5 | 2.26 | 1.88 |
| Kiko Calero | ChW | mr | 35 | .476 | 162 | .198 | 88 | .308 | 90 | .315 | 16.6 | 2.1 | 1.88 | 1.72 |
| Kevin Cameron | Min | mr | 30 | .490 | 15 | .333 | 7 | .280 | 7 | .280 | 1.5 | 2.1 | 1.92 | 1.57 |
| Shawn Camp | Det | mr | 34 | .686 | 352 | .293 | 200 | .403 | 210 | .423 | 48.4 | 3.6 | 3.25 | 3.25 |
| Matt Capps | Sea | cl | 26 | 1.015 | 255 | .388 | 224 | .622 | 228 | .633 | 77.6 | 9.1 | 8.41 | 8.48 |
| Chris Carpenter | NYY | sp | 35 | .649 | 671 | .283 | 367 | .393 | 370 | .397 | 86.1 | 3.4 | 3.05 | 3.10 |
| Alberto Castillo* |   | mr | 34 | 1.039 | 32 | .313 | 27 | .600 | 30 | .667 | 10.4 | 10.8 | 9.35 | 9.56 |
| Brett Cecil* | Tor | sp | 23 | .777 | 350 | .329 | 244 | .465 | 254 | .484 | 70.9 | 5.4 | 4.96 | 5.09 |
| Jhoulys Chacin | Cle | mr | 22 | .724 | 60 | .333 | 50 | .459 | 50 | .459 | 12.3 | 4.5 | 4.11 | 4.45 |
| Bruce Chen* | Cle | sp | 33 | .836 | 179 | .257 | 127 | .529 | 128 | .533 | 37.4 | 6.3 | 5.64 | 5.57 |
| Randy Choate* | Min | mr | 34 | .403 | 97 | .186 | 35 | .252 | 35 | .252 | 4.0 | 0.9 | 0.83 | 1.04 |
| Tyler Clippard | Sea | mr | 25 | .593 | 168 | .220 | 127 | .392 | 130 | .401 | 27.4 | 3.2 | 2.92 | 2.84 |
| Phil Coke* | Bal | mr | 27 | .689 | 163 | .221 | 111 | .449 | 113 | .457 | 24.6 | 3.5 | 3.20 | 2.95 |
| Bartolo Colon | Was | sp | 37 | .929 | 255 | .259 | 215 | .604 | 218 | .612 | 64.3 | 7.1 | 6.51 | 6.34 |
| Roman Colon | Cle | mr | 30 | .648 | 174 | .236 | 100 | .402 | 104 | .418 | 24.7 | 3.8 | 3.45 | 3.36 |
| Roy Corcoran | Det | mr | 30 | 1.303 | 19 | .368 | 26 | .788 | 26 | .788 | 10.4 | 18.8 | 16.90 | 20.73 |
| Francisco Cordero | Tex | cl | 35 | .697 | 217 | .332 | 126 | .410 | 126 | .410 | 34.7 | 4.6 | 4.11 | 4.37 |
| Lance Cormier | Det | mr | 29 | .670 | 310 | .255 | 168 | .413 | 171 | .420 | 42.4 | 3.9 | 3.52 | 3.19 |
| Kevin Correia | Mtl | sp | 29 | .798 | 609 | .323 | 397 | .482 | 400 | .486 | 116.1 | 5.7 | 5.13 | 5.35 |
| Juan Cruz | Cle | mr | 31 | .644 | 154 | .260 | 99 | .404 | 101 | .412 | 23.9 | 3.8 | 3.30 | 3.07 |
| Johnny Cueto | Sea | sp | 24 | .853 | 550 | .315 | 418 | .524 | 431 | .540 | 126.1 | 6.4 | 5.78 | 5.88 |
| John Danks* | NYY | sp | 25 | .753 | 583 | .259 | 431 | .484 | 436 | .489 | 110.8 | 4.7 | 4.22 | 4.13 |
| Wade Davis | Min | sp | 24 | .768 | 164 | .354 | 121 | .465 | 123 | .473 | 35.8 | 5.6 | 4.91 | 5.01 |
| Jorge de la Rosa* | Was | sp | 29 | .702 | 549 | .313 | 385 | .434 | 393 | .443 | 98.9 | 4.3 | 3.84 | 3.90 |
| Manny Delcarmen | Cle | mr | 28 | .765 | 207 | .246 | 140 | .490 | 142 | .497 | 37.2 | 5.1 | 4.56 | 4.26 |
| Ryan Dempster | LAA | sp | 33 | .770 | 561 | .299 | 405 | .486 | 408 | .490 | 107.5 | 5.0 | 4.57 | 4.48 |
| R.A. Dickey | LAA | mr | 35 | .825 | 283 | .346 | 193 | .490 | 198 | .503 | 58.1 | 6.0 | 5.37 | 5.75 |
| Mark DiFelice | Bos | mr | 33 | .694 | 127 | .260 | 81 | .448 | 81 | .448 | 20.3 | 4.1 | 3.80 | 2.98 |
| Brendan Donnelly | Bos | mr | 38 | .645 | 72 | .292 | 48 | .414 | 48 | .414 | 10.4 | 3.1 | 2.85 | 2.10 |
| Octavio Dotel | Bal | mr | 36 | .960 | 168 | .363 | 188 | .623 | 188 | .623 | 58.9 | 8.2 | 7.41 | 6.80 |
| Scott Downs* | Min | mr | 34 | .681 | 119 | .311 | 74 | .423 | 74 | .423 | 17.0 | 3.5 | 3.20 | 2.82 |
| Brian Duensing* | Bal | mr | 27 | .643 | 280 | .282 | 137 | .372 | 143 | .389 | 36.1 | 3.7 | 3.30 | 3.04 |
| Zach Duke* | Tor | sp | 27 | .861 | 663 | .323 | 452 | .529 | 458 | .536 | 138.8 | 6.6 | 5.95 | 5.83 |
| Scott Elbert* | Cle | mr | 24 | .850 | 40 | .225 | 37 | .597 | 37 | .597 | 8.4 | 4.8 | 4.23 | 3.91 |
| Kelvim Escobar | Mtl | sp | 34 | .928 | 72 | .347 | 63 | .543 | 68 | .586 | 21.6 | 8.3 | 7.19 | 8.25 |
| Dana Eveland* | LAA | sp | 26 | .925 | 222 | .383 | 168 | .556 | 168 | .556 | 53.4 | 7.5 | 6.72 | 7.55 |
| Scott Eyre* | Det | mr | 38 | .730 | 147 | .272 | 106 | .455 | 108 | .464 | 29.0 | 5.2 | 4.64 | 4.44 |
| Alfredo Figaro | NYY | sp | 25 | .754 | 24 | .292 | 19 | .475 | 19 | .475 | 5.6 | 5.6 | 5.00 | 5.02 |
| Doug Fister | Bos | sp | 26 | .772 | 151 | .245 | 97 | .480 | 101 | .500 | 25.3 | 4.8 | 4.34 | 4.40 |
| Randy Flores* | Mtl | mr | 34 | .972 | 6 | .167 | 8 | .667 | 8 | .667 | 2.4 | 9.3 | 8.36 | 9.66 |
| Josh Fogg | Bos | mr | 33 | .554 | 138 | .167 | 69 | .359 | 70 | .365 | 12.9 | 2.3 | 2.10 | 1.96 |
| Ryan Franklin | LAA | cl | 37 | .617 | 215 | .242 | 110 | .370 | 114 | .384 | 25.8 | 3.2 | 2.85 | 2.66 |
| Lucas French* | Det | sp | 24 | .980 | 315 | .378 | 268 | .596 | 272 | .604 | 98.9 | 10.1 | 9.06 | 8.90 |
| Ernesto Frieri | Mtl | mr | 24 | 1.667 | 1 | .000 | 4 | 1.333 | 4 | 1.333 | 1.3 | 18.0 | 16.20 | 15.46 |
| Jaime Garcia* | Sea | mr | 23 | 1.021 | 86 | .279 | 88 | .647 | 90 | .662 | 28.8 | 9.5 | 8.75 | 10.11 |
| Matt Garza | Bal | sp | 26 | .776 | 619 | .304 | 453 | .478 | 468 | .494 | 126.7 | 5.2 | 4.76 | 4.54 |
| Chad Gaudin | Sea | sp | 27 | .726 | 490 | .308 | 346 | .448 | 354 | .459 | 90.3 | 4.6 | 4.20 | 4.29 |
| Josh Geer | Tex | sp | 27 | 1.031 | 201 | .328 | 164 | .653 | 166 | .661 | 55.4 | 9.0 | 8.27 | 8.08 |
| Edgar Gonzalez | NYY | mr | 27 | 1.031 | 37 | .270 | 33 | .660 | 35 | .700 | 10.1 | 8.2 | 7.40 | 6.17 |
| Gio Gonzalez* | Sea | sp | 24 | .836 | 314 | .341 | 278 | .531 | 282 | .538 | 81.0 | 6.4 | 5.81 | 5.63 |
| Mike Gonzalez* | Cle | mr | 32 | .590 | 157 | .261 | 95 | .353 | 101 | .375 | 21.0 | 2.8 | 2.50 | 2.55 |
| Tom Gorzelanny* | Sea | mr | 27 | .720 | 176 | .301 | 119 | .451 | 119 | .451 | 31.6 | 4.6 | 4.15 | 4.06 |
| Mike Gosling* | Sea | mr | 29 | .869 | 83 | .253 | 64 | .577 | 64 | .577 | 16.9 | 5.7 | 5.12 | 4.73 |
| Sean Green | ChW | mr | 31 | .767 | 236 | .297 | 159 | .461 | 166 | .481 | 45.2 | 5.3 | 4.67 | 4.86 |
| Luke Gregerson | Mtl | mr | 26 | .583 | 238 | .315 | 130 | .341 | 134 | .352 | 30.8 | 2.9 | 2.60 | 2.19 |
| Kevin Gregg | Sea | cl | 32 | .640 | 224 | .223 | 138 | .409 | 140 | .415 | 31.2 | 3.4 | 3.11 | 2.82 |
| Zack Greinke | Bos | sp | 26 | .572 | 662 | .295 | 361 | .350 | 365 | .354 | 78.5 | 2.7 | 2.41 | 1.80 |
| Eddie Guardado* | LAA | mr | 39 | .618 | 124 | .250 | 65 | .361 | 70 | .389 | 17.5 | 3.7 | 3.40 | 3.10 |
| Matt Guerrier | Was | mr | 31 | .480 | 230 | .191 | 97 | .294 | 101 | .306 | 18.4 | 1.9 | 1.73 | 1.41 |
| Charlie Haeger | Cle | sp | 26 | .589 | 118 | .178 | 69 | .358 | 78 | .404 | 16.0 | 3.0 | 2.70 | 2.45 |
| Jason Hammel | ChW | sp | 27 | .890 | 632 | .362 | 451 | .532 | 464 | .548 | 150.7 | 7.3 | 6.54 | 6.21 |
| Mike Hampton* | Cle | sp | 37 | .706 | 448 | .286 | 273 | .439 | 274 | .441 | 68.0 | 4.1 | 3.70 | 3.54 |
| Joel Hanrahan | Tex | mr | 28 | .975 | 156 | .481 | 151 | .588 | 153 | .595 | 54.0 | 9.8 | 8.74 | 8.70 |
| Tommy Hanson | Was | sp | 23 | .677 | 476 | .256 | 291 | .425 | 297 | .434 | 70.5 | 3.8 | 3.38 | 3.20 |
| J.A. Happ* | LAA | sp | 27 | .809 | 477 | .289 | 341 | .501 | 349 | .512 | 100.0 | 5.9 | 5.31 | 5.41 |
| Aaron Harang | Tor | sp | 32 | .813 | 563 | .311 | 398 | .508 | 405 | .517 | 115.8 | 5.7 | 5.17 | 4.79 |
| Kevin Hart | Bos | sp | 27 | .764 | 70 | .314 | 47 | .475 | 47 | .475 | 11.9 | 4.6 | 4.20 | 4.11 |
| Blake Hawksworth | ChW | mr | 27 | .598 | 139 | .180 | 76 | .394 | 77 | .399 | 14.6 | 2.7 | 2.47 | 2.20 |
| Aaron Heilman | Sea | mr | 31 | .675 | 250 | .276 | 162 | .419 | 165 | .426 | 39.7 | 3.9 | 3.57 | 3.67 |
| Matt Herges | Min | mr | 40 | .450 | 22 | .136 | 9 | .300 | 9 | .300 | 1.3 | 1.4 | 1.17 | 1.25 |
| David Hernandez | ChW | sp | 25 | .941 | 146 | .356 | 118 | .581 | 118 | .581 | 39.3 | 8.3 | 7.52 | 7.33 |
| Felix Hernandez | Min | sp | 24 | .613 | 661 | .298 | 366 | .368 | 374 | .376 | 86.2 | 3.2 | 2.89 | 2.75 |
| Livan Hernandez | Oak | sp | 35 | .898 | 653 | .342 | 473 | .552 | 476 | .555 | 149.0 | 7.1 | 6.48 | 6.36 |
| Shawn Hill | Det | sp | 29 | 1.070 | 69 | .478 | 55 | .611 | 57 | .633 | 25.5 | 14.0 | 12.14 | 10.72 |
| Trevor Hoffman | ChW | cl | 42 | .591 | 180 | .206 | 95 | .375 | 95 | .375 | 19.7 | 2.7 | 2.46 | 2.21 |
| J.P. Howell* | Bos | mr | 27 | .564 | 158 | .272 | 92 | .333 | 99 | .359 | 20.2 | 2.6 | 2.36 | 2.10 |
| Tommy Hunter | KCR | sp | 23 | .740 | 469 | .275 | 277 | .460 | 279 | .463 | 69.7 | 4.3 | 3.94 | 3.76 |
| Edwin Jackson | Min | sp | 26 | .707 | 697 | .281 | 419 | .432 | 425 | .438 | 107.1 | 4.2 | 3.72 | 3.68 |
| Steven Jackson | Det | mr | 28 | .619 | 187 | .219 | 96 | .389 | 96 | .389 | 23.0 | 3.6 | 3.27 | 3.23 |
| Zach Jackson* | Mtl | mr | 27 | 1.118 | 36 | .528 | 38 | .667 | 38 | .667 | 16.5 | 14.3 | 12.12 | 12.18 |
| Chris Jakubauskas | Mtl | mr | 31 | .825 | 368 | .285 | 247 | .522 | 251 | .531 | 67.9 | 5.5 | 4.91 | 4.37 |
| Bobby Jenks | KCR | cl | 29 | .619 | 156 | .263 | 94 | .382 | 96 | .390 | 21.2 | 3.1 | 2.79 | 2.86 |
| Waldis Joaquin | ChW | mr | 23 | .939 | 28 | .357 | 21 | .467 | 23 | .511 | 8.6 | 9.3 | 8.76 | 9.32 |
| Jim Johnson | NYY | mr | 27 | .668 | 26 | .269 | 14 | .378 | 15 | .405 | 3.4 | 3.4 | 3.17 | 4.03 |
| Josh Johnson | Min | sp | 26 | .656 | 653 | .279 | 386 | .401 | 393 | .408 | 94.6 | 3.7 | 3.34 | 3.34 |
| Jair Jurrjens |   | sp | 24 | .764 | 680 | .321 | 420 | .458 | 424 | .462 | 117.2 | 5.0 | 4.55 | 4.68 |
| Scott Kazmir* | Bos | sp | 26 | .781 | 414 | .338 | 273 | .461 | 282 | .476 | 80.1 | 5.5 | 4.98 | 4.82 |
| Kyle Kendrick | Det | mr | 25 | .702 | 137 | .314 | 66 | .398 | 67 | .404 | 17.4 | 4.1 | 3.65 | 4.52 |
| Hong-Chih Kuo* | Bos | mr | 28 | .522 | 84 | .238 | 46 | .329 | 47 | .336 | 8.5 | 2.1 | 1.86 | 1.60 |
| John Lackey |   | sp | 31 | .720 | 606 | .304 | 368 | .432 | 377 | .443 | 97.7 | 4.3 | 3.92 | 3.81 |
| John Lannan* | Was | sp | 25 | .769 | 744 | .277 | 452 | .471 | 463 | .482 | 118.7 | 4.8 | 4.32 | 4.63 |
| Mat Latos | Bal | sp | 22 | .911 | 237 | .333 | 211 | .569 | 212 | .571 | 68.4 | 7.9 | 7.10 | 7.44 |
| Brandon League | Min | mr | 27 | .846 | 139 | .345 | 110 | .509 | 114 | .528 | 31.4 | 5.7 | 5.09 | 5.13 |
| Wade LeBlanc* | NYY | sp | 25 | .819 | 224 | .165 | 173 | .541 | 181 | .566 | 45.0 | 5.3 | 4.83 | 4.73 |
| Justin Lehr | Tex | sp | 32 | 1.089 | 59 | .424 | 50 | .649 | 50 | .649 | 20.6 | 12.9 | 11.36 | 12.14 |
| Jensen Lewis | Cle | mr | 26 | .887 | 196 | .286 | 197 | .590 | 198 | .593 | 54.1 | 6.4 | 5.84 | 5.55 |
| Matt Lindstrom | Sea | cl | 30 | .639 | 222 | .279 | 118 | .391 | 118 | .391 | 28.4 | 3.5 | 3.24 | 2.95 |
| Scott Linebrink | LAA | mr | 33 | .755 | 177 | .299 | 127 | .476 | 129 | .483 | 30.9 | 4.2 | 3.89 | 3.74 |
| Francisco Liriano* | Min | sp | 26 | .747 | 353 | .320 | 265 | .463 | 269 | .470 | 72.0 | 5.1 | 4.63 | 4.74 |
| Kyle Lohse |   | sp | 31 | .840 | 505 | .285 | 381 | .534 | 386 | .541 | 105.4 | 5.7 | 5.24 | 5.32 |
| Braden Looper | Tex | sp | 35 | 1.007 | 542 | .332 | 452 | .636 | 455 | .640 | 152.0 | 9.0 | 8.07 | 8.12 |
| Rodrigo Lopez | Sea | sp | 34 | .903 | 119 | .345 | 90 | .566 | 90 | .566 | 29.0 | 7.5 | 6.78 | 6.04 |
| Mark Lowe | Bos | mr | 27 | .774 | 193 | .316 | 145 | .482 | 147 | .488 | 39.9 | 5.3 | 4.90 | 4.58 |
| Paul Maholm* | NYY | sp | 28 | .877 | 493 | .349 | 362 | .540 | 364 | .543 | 109.5 | 6.6 | 5.92 | 6.12 |
| Robert Manuel | Cle | mr | 26 | .445 | 14 | .286 | 5 | .217 | 6 | .261 | 0.9 | 1.3 | 1.17 | 1.16 |
| Carlos Marmol | Bal | mr | 27 | .568 | 118 | .271 | 86 | .363 | 89 | .376 | 18.8 | 3.1 | 2.76 | 2.62 |
| Jason Marquis | Was | sp | 31 | .722 | 739 | .273 | 419 | .443 | 424 | .448 | 107.7 | 4.3 | 3.96 | 4.03 |
| Pedro Martinez | Was | sp | 38 | .860 | 200 | .350 | 156 | .513 | 166 | .546 | 52.3 | 7.1 | 6.26 | 5.56 |
| Shairon Martis | KCR | sp | 23 | .682 | 270 | .241 | 157 | .428 | 161 | .439 | 37.5 | 3.9 | 3.65 | 3.64 |
| Justin Masterson | NYY | mr | 25 | .828 | 161 | .354 | 120 | .502 | 123 | .515 | 34.5 | 5.6 | 5.11 | 5.36 |
| Brian Matusz* | Tex | sp | 23 | .805 | 206 | .306 | 152 | .512 | 153 | .515 | 41.3 | 5.3 | 4.80 | 4.63 |
| Brandon McCarthy | NYY | sp | 26 | .678 | 337 | .246 | 201 | .426 | 205 | .434 | 47.8 | 3.7 | 3.37 | 3.23 |
| Kyle McClellan | Bal | mr | 26 | .750 | 204 | .265 | 152 | .475 | 154 | .481 | 36.9 | 4.4 | 3.99 | 4.27 |
| Seth McClung | Tor | mr | 29 | .861 | 227 | .291 | 179 | .538 | 182 | .547 | 51.7 | 6.5 | 5.84 | 6.50 |
| Gil Meche | KCR | sp | 31 | .718 | 456 | .265 | 299 | .448 | 308 | .461 | 76.4 | 4.3 | 3.97 | 3.91 |
| Cla Meredith | LAA | mr | 27 | .887 | 271 | .351 | 187 | .530 | 190 | .538 | 59.4 | 6.8 | 6.17 | 6.73 |
| Randy Messenger | Det | mr | 28 | 1.044 | 92 | .457 | 74 | .627 | 74 | .627 | 27.7 | 10.2 | 9.33 | 10.47 |
| Dan Meyer* | NYY | mr | 28 | .501 | 32 | .219 | 16 | .320 | 16 | .320 | 2.9 | 2.0 | 1.88 | 1.83 |
| Kam Mickolio | ChW | mr | 26 | .532 | 49 | .224 | 25 | .342 | 25 | .342 | 5.2 | 2.6 | 2.33 | 1.81 |
| Andrew Miller* | LAA | sp | 25 | .820 | 315 | .337 | 224 | .496 | 229 | .507 | 66.6 | 6.1 | 5.58 | 5.44 |
| Trever Miller* | Was | mr | 37 | .579 | 24 | .250 | 12 | .353 | 12 | .353 | 2.8 | 2.9 | 2.59 | 2.08 |
| Kevin Millwood |   | sp | 35 | .831 | 653 | .283 | 471 | .525 | 478 | .533 | 130.3 | 5.6 | 5.11 | 4.99 |
| Eric Milton* | Sea | sp | 34 | .744 | 198 | .323 | 117 | .430 | 122 | .449 | 34.2 | 4.9 | 4.39 | 4.06 |
| Zach Miner | Det | mr | 28 | .900 | 243 | .358 | 195 | .540 | 199 | .551 | 60.1 | 7.2 | 6.57 | 7.98 |
| Brandon Morrow | NYY | cl | 25 | .722 | 184 | .299 | 140 | .450 | 143 | .460 | 36.7 | 4.7 | 4.23 | 4.68 |
| Clayton Mortensen | Mtl | sp | 25 | .856 | 172 | .273 | 120 | .519 | 126 | .545 | 35.5 | 6.4 | 5.83 | 5.93 |
| Charlie Morton | Det | sp | 26 | .952 | 342 | .377 | 283 | .586 | 285 | .590 | 93.2 | 8.3 | 7.50 | 7.55 |
| Guillermo Mota | NYY | mr | 36 | .724 | 163 | .264 | 97 | .441 | 102 | .464 | 25.4 | 4.3 | 3.86 | 3.52 |
| Jason Motte | Was | mr | 28 | .934 | 141 | .348 | 114 | .591 | 114 | .591 | 37.6 | 8.1 | 7.31 | 6.78 |
| Jamie Moyer* | NYY | sp | 47 | .745 | 35 | .343 | 17 | .386 | 19 | .432 | 4.9 | 4.4 | 3.94 | 5.07 |
| Edward Mujica | Min | mr | 26 | .838 | 173 | .295 | 137 | .546 | 137 | .546 | 38.9 | 6.0 | 5.34 | 4.75 |
| Brett Myers | Oak | sp | 29 | .804 | 260 | .250 | 197 | .513 | 203 | .529 | 53.2 | 5.3 | 4.91 | 4.99 |
| Chris Narveson* | KCR | mr | 28 | .936 | 156 | .378 | 138 | .573 | 140 | .581 | 47.5 | 8.7 | 7.84 | 7.11 |
| Joe Nelson | Bos | mr | 35 | .897 | 121 | .364 | 110 | .558 | 110 | .558 | 35.8 | 8.0 | 6.90 | 6.59 |
| Fu-Te Ni* | Bal | mr | 27 | .678 | 93 | .204 | 54 | .435 | 55 | .444 | 13.4 | 4.0 | 3.61 | 3.02 |
| Jonathon Niese* | ChW | sp | 23 | .876 | 121 | .339 | 103 | .551 | 103 | .551 | 30.3 | 6.6 | 5.93 | 6.12 |
| Fernando Nieve | LAA | sp | 27 | .931 | 185 | .378 | 144 | .558 | 145 | .562 | 49.9 | 8.4 | 7.77 | 8.35 |
| Dustin Nippert | ChW | sp | 29 | .640 | 242 | .260 | 129 | .379 | 135 | .397 | 29.7 | 3.2 | 2.88 | 3.16 |
| Bud Norris | Tor | sp | 25 | .812 | 156 | .295 | 135 | .519 | 138 | .531 | 38.2 | 6.0 | 5.40 | 5.50 |
| Hideki Okajima* | Was | mr | 34 | .552 | 185 | .232 | 98 | .346 | 100 | .353 | 19.6 | 2.4 | 2.21 | 1.94 |
| Garrett Olson* | LAA | mr | 26 | .643 | 149 | .195 | 83 | .405 | 86 | .420 | 17.8 | 3.1 | 2.85 | 2.72 |
| Russ Ortiz | Sea | sp | 36 | .896 | 298 | .366 | 221 | .534 | 228 | .551 | 72.6 | 7.4 | 6.69 | 6.82 |
| Vicente Padilla | KCR | sp | 32 | .711 | 566 | .300 | 329 | .420 | 341 | .435 | 84.2 | 4.0 | 3.71 | 3.95 |
| Jonathan Papelbon | Min | cl | 29 | .522 | 170 | .253 | 85 | .315 | 87 | .322 | 17.8 | 2.3 | 2.14 | 1.89 |
| Chan Ho Park | NYY | mr | 37 | .708 | 203 | .271 | 140 | .435 | 146 | .453 | 35.1 | 4.1 | 3.69 | 3.55 |
| Carl Pavano | Bal | sp | 34 | .882 | 718 | .348 | 511 | .535 | 519 | .543 | 159.8 | 6.7 | 6.06 | 5.90 |
| Jake Peavy | Oak | sp | 29 | .775 | 356 | .295 | 285 | .497 | 288 | .503 | 75.5 | 5.0 | 4.57 | 4.27 |
| Tony Pena | Oak | mr | 28 | .706 | 304 | .316 | 168 | .417 | 169 | .419 | 44.3 | 4.2 | 3.77 | 3.76 |
| Hayden Penn | Oak | mr | 25 | 1.353 | 24 | .542 | 32 | .762 | 34 | .810 | 15.4 | 21.9 | 17.82 | 18.63 |
| Chris Perez | Mtl | mr | 24 | .911 | 139 | .309 | 150 | .575 | 158 | .605 | 44.9 | 6.9 | 6.27 | 6.27 |
| Oliver Perez* | LAA | sp | 28 | .899 | 241 | .299 | 254 | .571 | 261 | .587 | 78.8 | 7.9 | 7.14 | 7.66 |
| Glen Perkins* | Oak | sp | 27 | .929 | 451 | .373 | 306 | .553 | 310 | .561 | 101.7 | 7.6 | 6.91 | 6.86 |
| Joel Pineiro | Bos | sp | 31 | .693 | 215 | .293 | 99 | .407 | 101 | .416 | 23.8 | 3.5 | 3.15 | 2.85 |
| Rick Porcello | ChW | sp | 21 | .760 | 680 | .304 | 411 | .459 | 417 | .466 | 110.4 | 4.7 | 4.24 | 4.41 |
| David Purcey* | ChW | sp | 28 | .886 | 286 | .318 | 240 | .557 | 242 | .561 | 74.9 | 7.4 | 6.84 | 6.79 |
| Horacio Ramirez* | Sea | mr | 30 | 1.208 | 47 | .319 | 49 | .766 | 50 | .781 | 19.7 | 15.2 | 14.05 | 12.41 |
| Ramon Ramirez | Oak | mr | 28 | .723 | 202 | .287 | 132 | .441 | 137 | .458 | 34.9 | 4.5 | 4.02 | 3.85 |
| Ramon Ramirez | Mtl | mr | 27 | 1.467 | 46 | .391 | 79 | .908 | 85 | .977 | 34.9 | 20.0 | 18.43 | 19.78 |
| Chris Ray | Mtl | mr | 28 | .976 | 153 | .366 | 135 | .608 | 135 | .608 | 45.1 | 8.6 | 7.73 | 7.59 |
| Robert Ray | Bal | sp | 26 | .655 | 107 | .224 | 56 | .368 | 64 | .421 | 15.7 | 3.9 | 3.51 | 3.50 |
| Tim Redding | Bos | sp | 32 | .758 | 291 | .285 | 184 | .463 | 188 | .474 | 51.3 | 5.0 | 4.56 | 4.42 |
| Chad Reineke | Mtl | sp | 28 | 1.271 | 39 | .462 | 46 | .697 | 52 | .788 | 20.5 | 16.7 | 14.20 | 15.93 |
| Dennys Reyes* | Oak | mr | 33 | .735 | 205 | .312 | 134 | .432 | 140 | .452 | 39.1 | 5.1 | 4.65 | 4.61 |
| Arthur Rhodes* | Tor | mr | 40 | .695 | 160 | .313 | 112 | .434 | 113 | .438 | 28.9 | 4.5 | 3.95 | 3.58 |
| Clayton Richard* | Tex | sp | 26 | .820 | 434 | .304 | 352 | .519 | 353 | .521 | 98.7 | 6.0 | 5.39 | 5.75 |
| Scott Richmond | Min | sp | 30 | .704 | 116 | .284 | 84 | .449 | 85 | .455 | 20.1 | 4.0 | 3.64 | 3.63 |
| Juan Rincon | NYY | mr | 31 | .762 | 15 | .267 | 12 | .500 | 12 | .500 | 2.8 | 4.4 | 3.75 | 4.01 |
| Mariano Rivera | LAA | cl | 40 | .533 | 182 | .253 | 93 | .330 | 96 | .340 | 17.8 | 2.1 | 1.95 | 1.52 |
| Nate Robertson* | Bos | mr | 32 | .713 | 262 | .305 | 151 | .418 | 154 | .427 | 42.1 | 4.6 | 4.14 | 4.22 |
| Francisco Rodriguez | Tor | cl | 28 | .479 | 180 | .156 | 93 | .320 | 95 | .326 | 16.7 | 2.0 | 1.80 | 1.44 |
| Henry Rodriguez | LAA | mr | 23 | .938 | 13 | .462 | 10 | .500 | 11 | .550 | 4.0 | 10.9 | 9.77 | 11.51 |
| Rafael Rodriguez | Tor | mr | 25 | .923 | 74 | .324 | 53 | .558 | 54 | .568 | 15.1 | 6.3 | 5.56 | 6.43 |
| Esmil Rogers | KCR | sp | 24 | .805 | 39 | .282 | 27 | .509 | 27 | .509 | 6.8 | 5.0 | 4.60 | 5.56 |
| Ricky Romero* | Cle | sp | 25 | .797 | 541 | .348 | 365 | .475 | 371 | .482 | 104.6 | 5.5 | 4.99 | 5.42 |
| Sergio Romo | Min | mr | 27 | .779 | 54 | .389 | 51 | .481 | 52 | .491 | 14.7 | 5.8 | 5.34 | 4.99 |
| Carlos Rosa | ChW | mr | 25 | .760 | 36 | .222 | 27 | .509 | 27 | .509 | 7.3 | 5.3 | 5.05 | 4.53 |
| Leo Rosales | Tor | mr | 29 | .667 | 146 | .240 | 88 | .417 | 90 | .427 | 18.8 | 3.2 | 2.85 | 2.77 |
| Ryan Rowland-Smith* | Det | sp | 27 | .815 | 283 | .290 | 188 | .503 | 191 | .511 | 54.9 | 5.8 | 5.30 | 4.79 |
| B.J. Ryan* | Tor | mr | 34 | 1.080 | 41 | .415 | 41 | .641 | 42 | .656 | 15.2 | 11.8 | 10.58 | 11.71 |
| Marc Rzepczynski* | Det | sp | 24 | .709 | 234 | .265 | 157 | .447 | 159 | .453 | 34.2 | 3.5 | 3.23 | 3.92 |
| C.C. Sabathia* | Oak | sp | 29 | .625 | 751 | .285 | 396 | .374 | 402 | .379 | 91.2 | 3.1 | 2.82 | 2.70 |
| Brian Sanches | Det | mr | 31 | .674 | 259 | .266 | 152 | .398 | 163 | .427 | 38.2 | 3.7 | 3.43 | 3.48 |
| Ervin Santana |   | sp | 27 | .829 | 467 | .296 | 336 | .513 | 343 | .524 | 97.1 | 5.8 | 5.23 | 5.46 |
| Johan Santana* | Sea | sp | 31 | .683 | 609 | .279 | 386 | .425 | 395 | .435 | 95.7 | 3.9 | 3.52 | 3.18 |
| Dennis Sarfate | NYY | mr | 29 | .955 | 9 | .444 | 6 | .545 | 6 | .545 | 2.4 | 10.8 | 9.68 | 9.72 |
| Joe Saunders* | LAA | sp | 29 | .772 | 585 | .279 | 372 | .476 | 378 | .483 | 100.6 | 4.9 | 4.50 | 4.65 |
| Max Scherzer | Tor | sp | 25 | .830 | 496 | .349 | 407 | .513 | 417 | .526 | 121.9 | 6.2 | 5.60 | 5.28 |
| Daniel Schlereth* | Det | mr | 24 | .742 | 81 | .358 | 77 | .472 | 77 | .472 | 21.0 | 5.4 | 4.90 | 5.05 |
| George Sherrill* | KCR | cl | 33 | .602 | 201 | .284 | 110 | .365 | 112 | .372 | 25.3 | 3.0 | 2.76 | 2.26 |
| Brian Shouse* | Bal | mr | 41 | 1.176 | 42 | .405 | 43 | .705 | 45 | .738 | 15.0 | 10.7 | 9.12 | 10.60 |
| Tony Sipp* | Cle | mr | 26 | .548 | 102 | .167 | 67 | .374 | 69 | .385 | 12.6 | 2.5 | 2.29 | 2.07 |
| Doug Slaten* | Tex | mr | 30 | .627 | 15 | .267 | 6 | .333 | 6 | .333 | 1.4 | 2.7 | 2.62 | 2.34 |
| Kevin Slowey | Tor | sp | 26 | .879 | 344 | .360 | 282 | .536 | 293 | .557 | 90.0 | 7.0 | 6.31 | 5.86 |
| Joe Smith | Tor | mr | 26 | .815 | 110 | .327 | 97 | .516 | 98 | .521 | 28.6 | 6.2 | 5.60 | 5.09 |
| John Smoltz | Mtl | sp | 43 | .852 | 340 | .353 | 254 | .517 | 260 | .530 | 80.8 | 6.8 | 6.02 | 5.38 |
| Ian Snell | Tex | sp | 28 | .802 | 589 | .314 | 397 | .496 | 400 | .500 | 116.0 | 5.8 | 5.31 | 4.97 |
| Rafael Soriano | NYY | cl | 30 | .527 | 127 | .276 | 77 | .328 | 78 | .332 | 16.8 | 2.6 | 2.33 | 2.09 |
| Jorge Sosa | Det | mr | 33 | 1.209 | 17 | .353 | 20 | .741 | 21 | .778 | 7.7 | 13.8 | 14.37 | 16.06 |
| Justin Speier | Mtl | mr | 36 | .921 | 119 | .345 | 106 | .570 | 109 | .586 | 35.1 | 7.9 | 7.11 | 7.41 |
| Russ Springer | Tor | mr | 41 | .854 | 232 | .366 | 177 | .516 | 179 | .522 | 57.1 | 6.8 | 6.14 | 5.76 |
| Craig Stammen | Tex | sp | 26 | .700 | 493 | .235 | 278 | .441 | 283 | .449 | 70.3 | 4.1 | 3.71 | 3.32 |
| Mitch Stetter* | Was | mr | 29 | .699 | 69 | .275 | 41 | .418 | 43 | .439 | 11.5 | 4.7 | 4.23 | 3.65 |
| Jeff Stevens | Cle | mr | 26 | .473 | 8 | .250 | 3 | .273 | 3 | .273 | 0.6 | 2.1 | 1.87 | 2.01 |
| Brian Stokes | Was | mr | 30 | .716 | 169 | .272 | 100 | .439 | 103 | .452 | 25.1 | 4.2 | 3.81 | 3.89 |
| Jeff Suppan | Bal | sp | 35 | .965 | 540 | .343 | 413 | .584 | 424 | .600 | 132.7 | 7.9 | 7.18 | 7.83 |
| Ken Takahashi* | Oak | mr | 41 | .764 | 65 | .323 | 50 | .476 | 51 | .486 | 13.5 | 5.1 | 4.43 | 3.61 |
| Brian Tallet* | Oak | sp | 32 | .815 | 531 | .316 | 395 | .506 | 402 | .515 | 114.9 | 5.9 | 5.30 | 4.89 |
| Julian Tavarez | Oak | mr | 37 | .675 | 200 | .270 | 126 | .423 | 127 | .426 | 31.2 | 4.2 | 3.77 | 3.69 |
| Dale Thayer | Mtl | mr | 29 | .975 | 47 | .340 | 35 | .625 | 35 | .625 | 11.6 | 8.5 | 8.07 | 7.46 |
| Rich Thompson | Mtl | mr | 25 | 1.033 | 90 | .444 | 84 | .636 | 85 | .644 | 30.8 | 10.3 | 9.03 | 9.22 |
| Brett Tomko | Cle | mr | 37 | .796 | 163 | .245 | 111 | .514 | 113 | .523 | 29.7 | 5.2 | 4.75 | 4.45 |
| Ramon Troncoso | Tex | mr | 27 | .639 | 311 | .277 | 156 | .375 | 160 | .385 | 37.4 | 3.3 | 2.99 | 3.26 |
| Jose Valverde | KCR | cl | 30 | .570 | 148 | .230 | 89 | .369 | 90 | .373 | 18.0 | 2.7 | 2.43 | 2.25 |
| Jason Vargas* | Bal | sp | 27 | .937 | 301 | .362 | 229 | .575 | 231 | .580 | 77.6 | 8.2 | 7.33 | 6.90 |
| Donald Veal* | LAA | mr | 25 | .902 | 24 | .292 | 26 | .591 | 26 | .591 | 7.1 | 7.1 | 6.15 | 7.76 |
| Justin Verlander | Cle | sp | 27 | .707 | 612 | .348 | 411 | .428 | 417 | .434 | 109.8 | 4.3 | 3.85 | 3.52 |
| Ron Villone* | Tex | mr | 40 | .709 | 161 | .280 | 107 | .446 | 109 | .454 | 27.6 | 4.5 | 4.07 | 3.67 |
| Luis Vizcaino | ChW | mr | 35 | .477 | 52 | .154 | 22 | .306 | 22 | .306 | 4.3 | 2.1 | 1.93 | 1.59 |
| Edinson Volquez | Mtl | sp | 26 | .840 | 215 | .312 | 173 | .509 | 182 | .535 | 53.1 | 6.6 | 5.95 | 6.01 |
| Chris Volstad | KCR | sp | 23 | .869 | 529 | .314 | 403 | .545 | 406 | .549 | 116.4 | 6.2 | 5.68 | 6.01 |
| Billy Wagner* | Tor | mr | 38 | .778 | 27 | .556 | 28 | .459 | 29 | .475 | 9.0 | 6.6 | 5.75 | 5.53 |
| Tim Wakefield | Min | sp | 43 | .736 | 532 | .271 | 320 | .446 | 330 | .460 | 86.9 | 4.7 | 4.37 | 4.48 |
| Tyler Walker | Min | mr | 34 | .575 | 46 | .261 | 23 | .343 | 24 | .358 | 5.5 | 3.0 | 2.70 | 2.37 |
| Jarrod Washburn* | Bos | sp | 35 | .756 | 603 | .287 | 363 | .464 | 371 | .474 | 96.2 | 4.7 | 4.23 | 4.06 |
| David Weathers | Oak | mr | 40 | .839 | 256 | .227 | 207 | .549 | 211 | .560 | 55.3 | 5.7 | 5.25 | 5.01 |
| Jeff Weaver | Was | mr | 33 | .563 | 181 | .238 | 85 | .336 | 89 | .352 | 20.5 | 2.9 | 2.66 | 2.06 |
| Brandon Webb | NYY | sp | 31 | 1.556 | 5 | .400 | 8 | .889 | 9 | 1.000 | 4.2 | 28.2 | 25.38 | 25.37 |
| Ryan Webb | Was | mr | 24 | .888 | 35 | .314 | 26 | .510 | 28 | .549 | 8.8 | 7.6 | 6.45 | 7.30 |
| Todd Wellemeyer | Det | sp | 31 | .988 | 343 | .370 | 291 | .604 | 294 | .610 | 100.5 | 9.1 | 8.14 | 8.95 |
| Randy Williams* | Mtl | mr | 34 | .609 | 35 | .286 | 23 | .354 | 26 | .400 | 5.7 | 3.7 | 3.45 | 3.76 |
| Dontrelle Willis* | Mtl | sp | 28 | .886 | 44 | .341 | 28 | .509 | 28 | .509 | 10.4 | 8.2 | 7.42 | 6.96 |
| C.J. Wilson* | KCR | mr | 29 | .655 | 213 | .296 | 137 | .397 | 142 | .412 | 33.0 | 3.7 | 3.37 | 3.44 |
| Randy Wolf* | ChW | sp | 33 | .766 | 667 | .300 | 436 | .463 | 445 | .472 | 120.5 | 5.0 | 4.46 | 4.52 |
| Kerry Wood | Det | cl | 33 | .804 | 124 | .306 | 115 | .513 | 118 | .527 | 30.2 | 5.1 | 4.59 | 4.78 |
| Tim Wood | KCR | mr | 27 | .789 | 81 | .370 | 51 | .464 | 51 | .464 | 13.7 | 4.9 | 4.45 | 5.60 |
| Michael Wuertz | Tex | mr | 31 | .527 | 241 | .282 | 136 | .327 | 137 | .329 | 29.0 | 2.5 | 2.21 | 1.48 |
| Yasuhiko Yabuta | Cle | mr | 37 | 1.479 | 21 | .619 | 25 | .926 | 25 | .926 | 13.5 | 30.3 | 27.29 | 22.74 |
| Clay Zavada* | Mtl | mr | 26 | .574 | 173 | .225 | 95 | .367 | 96 | .371 | 19.2 | 2.6 | 2.37 | 2.18 |
| Brad Ziegler | NYY | mr | 30 | .683 | 141 | .362 | 69 | .367 | 71 | .378 | 16.8 | 3.3 | 2.96 | 3.75 |
| Jordan Zimmermann | Bal | sp | 24 | .770 | 360 | .336 | 263 | .472 | 270 | .485 | 72.8 | 5.1 | 4.62 | 4.48 |
| Barry Zito* | ChW | sp | 32 | .797 | 589 | .351 | 419 | .481 | 425 | .487 | 120.1 | 5.6 | 5.00 | 5.42 |
| Joel Zumaya | NYY | mr | 25 | .857 | 72 | .264 | 62 | .549 | 63 | .558 | 17.9 | 6.6 | 5.95 | 6.27 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 | 12.4 | .596 |
| Alfredo Aceves | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 23.2 | .686 |
| Nick Adenhart | Bal | sp | 23 | 5 | 1 | .200 | 0 | 4 | .800 | 23 | 4.6 | 4 | 3 | .750 | 92.4 | .597 |
| Jeremy Affeldt* | NYY | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 17.4 | .594 |
| Matt Albers | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 30.1 | .591 |
| Jose Arredondo | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 17.2 | .610 |
| Jose Ascanio | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 24.3 | .637 |
| John Axford | Cle | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 27.2 | .537 |
| Burke Badenhop | KCR | mr | 27 | 1 | 0 | .000 | 0 | 1 | 1.000 | 8 | 8.0 | 16 | 9 | .563 | 37.3 | .636 |
| Danys Baez | Min | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 19.2 | .632 |
| Homer Bailey | Tor | sp | 24 | 22 | 0 | .000 | 0 | 9 | .409 | 98 | 4.5 | 26 | 7 | .269 | 97.8 | .603 |
| John Bale* | Sea | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 22.5 | .544 |
| Josh Banks | Mtl | sp | 27 | 6 | 0 | .000 | 0 | 1 | .167 | 17 | 2.8 | 11 | 3 | .273 | 56.0 | .719 |
| Daniel Bard | Tor | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 | 24.7 | .590 |
| Brian Bass | LAA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 35.1 | .616 |
| Miguel Batista | Bal | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 15 | .349 | 28.3 | .603 |
| Josh Beckett | KCR | sp | 30 | 32 | 4 | .125 | 1 | 20 | .625 | 129 | 4.0 | 21 | 5 | .238 | 106.9 | .635 |
| Joe Beimel* |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 1 | .059 | 16.4 | .635 |
| Trevor Bell | LAA | sp | 23 | 7 | 0 | .000 | 0 | 1 | .143 | 26 | 3.7 | 10 | 4 | .400 | 86.6 | .601 |
| Kris Benson | Oak | mr | 35 | 6 | 0 | .000 | 0 | 2 | .333 | 28 | 4.7 | 6 | 1 | .167 | 109.2 | .589 |
| Brad Bergesen | Tex | sp | 24 | 24 | 3 | .125 | 1 | 17 | .708 | 137 | 5.7 | 14 | 6 | .429 | 99.5 | .656 |
| Jason Berken | Oak | sp | 26 | 5 | 0 | .000 | 0 | 1 | .200 | 23 | 4.6 | 4 | 2 | .500 | 83.6 | .629 |
| Rafael Betancourt | NYY | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 15.8 | .621 |
| Jerry Blevins* | Mtl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 18.6 | .638 |
| Mitchell Boggs | Det | sp | 26 | 20 | 0 | .000 | 0 | 3 | .150 | 79 | 4.0 | 25 | 7 | .280 | 79.5 | .550 |
| Blaine Boyer | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 22.1 | .575 |
| Dallas Braden* | Mtl | sp | 26 | 26 | 2 | .077 | 0 | 15 | .577 | 111 | 4.3 | 16 | 4 | .250 | 103.2 | .650 |
| Doug Brocail | Det | mr | 43 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 9 | .529 | 28.9 | .527 |
| Brian Bruney | ChW | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 17.2 | .583 |
| Clay Buchholz | Cle | sp | 25 | 20 | 1 | .050 | 0 | 8 | .400 | 109 | 5.4 | 11 | 4 | .364 | 103.9 | .621 |
| Jason Bulger | KCR | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 | 24.3 | .603 |
| Madison Bumgarner* | Sea | mr | 20 | 6 | 0 | .000 | 0 | 2 | .333 | 27 | 4.5 | 8 | 0 | .000 | 93.8 | .604 |
| Greg Burke | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 25.4 | .618 |
| Tim Byrdak* | Bos | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 23.3 | .582 |
| Kiko Calero | ChW | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 | 19.8 | .601 |
| Kevin Cameron | Min | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 14.4 | .653 |
| Shawn Camp | Det | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 3 | .115 | 33.3 | .615 |
| Matt Capps | Sea | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 5 | .208 | 31.0 | .642 |
| Chris Carpenter | NYY | sp | 35 | 30 | 9 | .300 | 2 | 22 | .733 | 184 | 6.1 | 18 | 11 | .611 | 113.6 | .661 |
| Alberto Castillo* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 16.9 | .592 |
| Brett Cecil* | Tor | sp | 23 | 21 | 0 | .000 | 0 | 11 | .524 | 108 | 5.1 | 27 | 7 | .259 | 95.2 | .600 |
| Jhoulys Chacin | Cle | mr | 22 | 5 | 0 | .000 | 0 | 1 | .200 | 32 | 6.4 | 7 | 5 | .714 | 94.2 | .550 |
| Bruce Chen* | Cle | sp | 33 | 5 | 0 | .000 | 0 | 1 | .200 | 22 | 4.4 | 13 | 3 | .231 | 35.3 | .607 |
| Randy Choate* | Min | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 15.7 | .635 |
| Tyler Clippard | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 31.8 | .580 |
| Phil Coke* | Bal | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 | 15.5 | .642 |
| Bartolo Colon | Was | sp | 37 | 14 | 0 | .000 | 0 | 3 | .214 | 54 | 3.9 | 8 | 3 | .375 | 93.9 | .627 |
| Roman Colon | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 | 21.9 | .611 |
| Roy Corcoran | Det | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 33.3 | .466 |
| Francisco Cordero | Tex | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 | 19.5 | .591 |
| Lance Cormier | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 29.0 | .640 |
| Kevin Correia | Mtl | sp | 29 | 32 | 0 | .000 | 0 | 13 | .406 | 141 | 4.4 | 22 | 11 | .500 | 95.1 | .616 |
| Juan Cruz | Cle | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 11 | .458 | 20.4 | .596 |
| Johnny Cueto | Sea | sp | 24 | 30 | 2 | .067 | 1 | 12 | .400 | 138 | 4.6 | 31 | 12 | .387 | 98.3 | .617 |
| John Danks* | NYY | sp | 25 | 32 | 1 | .031 | 0 | 19 | .594 | 177 | 5.5 | 26 | 10 | .385 | 105.1 | .617 |
| Wade Davis | Min | sp | 24 | 10 | 1 | .100 | 0 | 6 | .600 | 71 | 7.1 | 7 | 3 | .429 | 98.0 | .641 |
| Jorge de la Rosa* | Was | sp | 29 | 32 | 3 | .094 | 1 | 22 | .688 | 160 | 5.0 | 25 | 4 | .160 | 109.1 | .610 |
| Manny Delcarmen | Cle | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 16.7 | .579 |
| Ryan Dempster | LAA | sp | 33 | 31 | 1 | .032 | 0 | 13 | .419 | 129 | 4.2 | 16 | 2 | .125 | 103.2 | .616 |
| R.A. Dickey | LAA | mr | 35 | 2 | 0 | .000 | 0 | 0 | .000 | 10 | 5.0 | 22 | 12 | .545 | 38.2 | .608 |
| Mark DiFelice | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 | 28.0 | .664 |
| Brendan Donnelly | Bos | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 22.0 | .655 |
| Octavio Dotel | Bal | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 18.0 | .582 |
| Scott Downs* | Min | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 3 | .125 | 15.6 | .654 |
| Brian Duensing* | Bal | mr | 27 | 12 | 5 | .417 | 1 | 10 | .833 | 49 | 4.1 | 9 | 3 | .333 | 106.4 | .648 |
| Zach Duke* | Tor | sp | 27 | 30 | 4 | .133 | 0 | 10 | .333 | 126 | 4.2 | 25 | 3 | .120 | 93.4 | .646 |
| Scott Elbert* | Cle | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 14.9 | .646 |
| Kelvim Escobar | Mtl | sp | 34 | 5 | 0 | .000 | 0 | 1 | .200 | 13 | 2.6 | 4 | 4 | 1.000 | 84.6 | .556 |
| Dana Eveland* | LAA | sp | 26 | 13 | 0 | .000 | 0 | 3 | .231 | 54 | 4.2 | 19 | 5 | .263 | 90.5 | .583 |
| Scott Eyre* | Det | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 22.4 | .554 |
| Alfredo Figaro | NYY | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 50.7 | .625 |
| Doug Fister | Bos | sp | 26 | 8 | 1 | .125 | 0 | 4 | .500 | 48 | 6.0 | 7 | 1 | .143 | 92.4 | .624 |
| Randy Flores* | Mtl | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 15.7 | .532 |
| Josh Fogg | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 34.5 | .619 |
| Ryan Franklin | LAA | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 21.2 | .637 |
| Lucas French* | Det | sp | 24 | 21 | 0 | .000 | 0 | 1 | .048 | 64 | 3.0 | 32 | 11 | .344 | 80.1 | .596 |
| Ernesto Frieri | Mtl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 9.0 | .889 |
| Jaime Garcia* | Sea | mr | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 35 | 5.8 | 7 | 1 | .143 | 90.0 | .559 |
| Matt Garza | Bal | sp | 26 | 32 | 5 | .156 | 2 | 15 | .469 | 155 | 4.8 | 25 | 6 | .240 | 112.5 | .622 |
| Chad Gaudin | Sea | sp | 27 | 29 | 1 | .034 | 0 | 13 | .448 | 151 | 5.2 | 25 | 15 | .600 | 89.8 | .591 |
| Josh Geer | Tex | sp | 27 | 10 | 0 | .000 | 0 | 4 | .400 | 48 | 4.8 | 4 | 2 | .500 | 86.2 | .683 |
| Edgar Gonzalez | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 44.8 | .603 |
| Gio Gonzalez* | Sea | sp | 24 | 22 | 0 | .000 | 0 | 6 | .273 | 123 | 5.6 | 21 | 7 | .333 | 95.4 | .593 |
| Mike Gonzalez* | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 3 | .130 | 19.3 | .618 |
| Tom Gorzelanny* | Sea | mr | 27 | 11 | 0 | .000 | 0 | 6 | .545 | 48 | 4.4 | 10 | 4 | .400 | 80.6 | .619 |
| Mike Gosling* | Sea | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 30.2 | .628 |
| Sean Green | ChW | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 11 | .379 | 24.1 | .579 |
| Luke Gregerson | Mtl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 24.3 | .653 |
| Kevin Gregg | Sea | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 23.5 | .628 |
| Zack Greinke | Bos | sp | 26 | 33 | 17 | .515 | 7 | 28 | .848 | 137 | 4.2 | 10 | 3 | .300 | 115.8 | .668 |
| Eddie Guardado* | LAA | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 24.6 | .620 |
| Matt Guerrier | Was | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 18.4 | .656 |
| Charlie Haeger | Cle | sp | 26 | 7 | 1 | .143 | 1 | 6 | .857 | 21 | 3.0 | 2 | 0 | .000 | 107.1 | .603 |
| Jason Hammel | ChW | sp | 27 | 30 | 2 | .067 | 0 | 10 | .333 | 165 | 5.5 | 34 | 14 | .412 | 96.5 | .658 |
| Mike Hampton* | Cle | sp | 37 | 25 | 1 | .040 | 1 | 14 | .560 | 119 | 4.8 | 8 | 3 | .375 | 92.6 | .632 |
| Joel Hanrahan | Tex | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 8 | .364 | 21.4 | .590 |
| Tommy Hanson | Was | sp | 23 | 25 | 5 | .200 | 1 | 16 | .640 | 154 | 6.2 | 9 | 2 | .222 | 103.3 | .616 |
| J.A. Happ* | LAA | sp | 27 | 27 | 1 | .037 | 0 | 10 | .370 | 140 | 5.2 | 17 | 8 | .471 | 94.5 | .606 |
| Aaron Harang | Tor | sp | 32 | 29 | 2 | .069 | 0 | 9 | .310 | 134 | 4.6 | 26 | 13 | .500 | 97.7 | .650 |
| Kevin Hart | Bos | sp | 27 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 6 | 0 | .000 | 60.0 | .557 |
| Blake Hawksworth | ChW | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 2 | .087 | 16.5 | .604 |
| Aaron Heilman | Sea | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 23.9 | .579 |
| Matt Herges | Min | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 34.3 | .602 |
| David Hernandez | ChW | sp | 25 | 8 | 0 | .000 | 0 | 2 | .250 | 45 | 5.6 | 8 | 1 | .125 | 88.9 | .633 |
| Felix Hernandez | Min | sp | 24 | 34 | 8 | .235 | 2 | 24 | .706 | 212 | 6.2 | 22 | 6 | .273 | 111.4 | .633 |
| Livan Hernandez | Oak | sp | 35 | 31 | 2 | .065 | 0 | 11 | .355 | 143 | 4.6 | 25 | 10 | .400 | 96.6 | .628 |
| Shawn Hill | Det | sp | 29 | 5 | 0 | .000 | 0 | 1 | .200 | 16 | 3.2 | 6 | 2 | .333 | 66.4 | .663 |
| Trevor Hoffman | ChW | cl | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 2 | .111 | 15.0 | .645 |
| J.P. Howell* | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 20.6 | .616 |
| Tommy Hunter | KCR | sp | 23 | 22 | 3 | .136 | 1 | 11 | .500 | 106 | 4.8 | 15 | 4 | .267 | 97.4 | .648 |
| Edwin Jackson | Min | sp | 26 | 33 | 4 | .121 | 0 | 22 | .667 | 201 | 6.1 | 25 | 8 | .320 | 106.5 | .628 |
| Steven Jackson | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 26.8 | .576 |
| Zach Jackson* | Mtl | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 3 | 1.5 | 2 | 1 | .500 | 111.0 | .604 |
| Chris Jakubauskas | Mtl | mr | 31 | 12 | 0 | .000 | 0 | 7 | .583 | 42 | 3.5 | 12 | 8 | .667 | 63.0 | .635 |
| Bobby Jenks | KCR | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 17.6 | .654 |
| Waldis Joaquin | ChW | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 15.9 | .553 |
| Jim Johnson | NYY | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 14.6 | .634 |
| Josh Johnson | Min | sp | 26 | 33 | 6 | .182 | 1 | 21 | .636 | 195 | 5.9 | 26 | 6 | .231 | 111.0 | .635 |
| Jair Jurrjens |   | sp | 24 | 34 | 2 | .059 | 1 | 18 | .529 | 171 | 5.0 | 32 | 10 | .313 | 101.4 | .607 |
| Scott Kazmir* | Bos | sp | 26 | 23 | 0 | .000 | 0 | 9 | .391 | 101 | 4.4 | 18 | 1 | .056 | 98.5 | .607 |
| Kyle Kendrick | Det | mr | 25 | 6 | 0 | .000 | 0 | 3 | .500 | 16 | 2.7 | 10 | 2 | .200 | 99.8 | .623 |
| Hong-Chih Kuo* | Bos | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 21.0 | .604 |
| John Lackey |   | sp | 31 | 30 | 3 | .100 | 0 | 18 | .600 | 134 | 4.5 | 22 | 7 | .318 | 103.3 | .636 |
| John Lannan* | Was | sp | 25 | 33 | 6 | .182 | 1 | 13 | .394 | 160 | 4.8 | 27 | 11 | .407 | 100.0 | .619 |
| Mat Latos | Bal | sp | 22 | 14 | 0 | .000 | 0 | 5 | .357 | 72 | 5.1 | 8 | 3 | .375 | 102.0 | .593 |
| Brandon League | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 23.3 | .622 |
| Wade LeBlanc* | NYY | sp | 25 | 13 | 0 | .000 | 0 | 6 | .462 | 65 | 5.0 | 11 | 6 | .545 | 90.7 | .595 |
| Justin Lehr | Tex | sp | 32 | 3 | 0 | .000 | 0 | 0 | .000 | 8 | 2.7 | 5 | 2 | .400 | 90.7 | .632 |
| Jensen Lewis | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 | 23.1 | .592 |
| Matt Lindstrom | Sea | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 0 | .000 | 27.9 | .616 |
| Scott Linebrink | LAA | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 24.1 | .642 |
| Francisco Liriano* | Min | sp | 26 | 21 | 0 | .000 | 0 | 10 | .476 | 119 | 5.7 | 30 | 11 | .367 | 80.0 | .589 |
| Kyle Lohse |   | sp | 31 | 29 | 1 | .034 | 0 | 14 | .483 | 122 | 4.2 | 23 | 12 | .522 | 88.8 | .623 |
| Braden Looper | Tex | sp | 35 | 29 | 2 | .069 | 0 | 7 | .241 | 143 | 4.9 | 17 | 9 | .529 | 86.6 | .625 |
| Rodrigo Lopez | Sea | sp | 34 | 1 | 0 | .000 | 0 | 1 | 1.000 | 7 | 7.0 | 8 | 4 | .500 | 39.4 | .667 |
| Mark Lowe | Bos | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 13 | .371 | 26.7 | .605 |
| Paul Maholm* | NYY | sp | 28 | 26 | 2 | .077 | 1 | 7 | .269 | 132 | 5.1 | 19 | 3 | .158 | 92.8 | .636 |
| Robert Manuel | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 32.7 | .643 |
| Carlos Marmol | Bal | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 19.8 | .549 |
| Jason Marquis | Was | sp | 31 | 32 | 5 | .156 | 1 | 18 | .563 | 170 | 5.3 | 19 | 8 | .421 | 107.2 | .610 |
| Pedro Martinez | Was | sp | 38 | 13 | 1 | .077 | 1 | 6 | .462 | 95 | 7.3 | 13 | 1 | .077 | 84.7 | .647 |
| Shairon Martis | KCR | sp | 23 | 15 | 1 | .067 | 0 | 7 | .467 | 86 | 5.7 | 16 | 5 | .313 | 87.9 | .587 |
| Justin Masterson | NYY | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 31.5 | .628 |
| Brian Matusz* | Tex | sp | 23 | 12 | 1 | .083 | 0 | 6 | .500 | 66 | 5.5 | 7 | 6 | .857 | 90.9 | .658 |
| Brandon McCarthy | NYY | sp | 26 | 19 | 1 | .053 | 1 | 9 | .474 | 99 | 5.2 | 17 | 7 | .412 | 91.7 | .625 |
| Kyle McClellan | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 | 18.6 | .580 |
| Seth McClung | Tor | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 10 | .294 | 27.3 | .562 |
| Gil Meche | KCR | sp | 31 | 27 | 1 | .037 | 0 | 8 | .296 | 120 | 4.4 | 19 | 2 | .105 | 93.6 | .599 |
| Cla Meredith | LAA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 23.7 | .638 |
| Randy Messenger | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 29.3 | .688 |
| Dan Meyer* | NYY | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 9.8 | .605 |
| Kam Mickolio | ChW | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 6 | .273 | 12.9 | .609 |
| Andrew Miller* | LAA | sp | 25 | 20 | 0 | .000 | 0 | 6 | .300 | 106 | 5.3 | 21 | 7 | .333 | 84.6 | .585 |
| Trever Miller* | Was | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 11.0 | .636 |
| Kevin Millwood |   | sp | 35 | 34 | 1 | .029 | 0 | 15 | .441 | 135 | 4.0 | 17 | 1 | .059 | 94.8 | .613 |
| Eric Milton* | Sea | sp | 34 | 10 | 1 | .100 | 0 | 5 | .500 | 55 | 5.5 | 9 | 2 | .222 | 100.6 | .654 |
| Zach Miner | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 18 | .474 | 38.3 | .557 |
| Brandon Morrow | NYY | cl | 25 | 10 | 0 | .000 | 0 | 4 | .400 | 64 | 6.4 | 14 | 4 | .286 | 62.9 | .568 |
| Clayton Mortensen | Mtl | sp | 25 | 8 | 0 | .000 | 0 | 1 | .125 | 27 | 3.4 | 15 | 6 | .400 | 38.3 | .595 |
| Charlie Morton | Det | sp | 26 | 22 | 0 | .000 | 0 | 6 | .273 | 108 | 4.9 | 22 | 9 | .409 | 80.5 | .589 |
| Guillermo Mota | NYY | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 17.9 | .639 |
| Jason Motte | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 18.1 | .640 |
| Jamie Moyer* | NYY | sp | 47 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 3 | 2 | .667 | 80.0 | .625 |
| Edward Mujica | Min | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 25.4 | .677 |
| Brett Myers | Oak | sp | 29 | 14 | 3 | .214 | 0 | 7 | .500 | 64 | 4.6 | 8 | 5 | .625 | 98.4 | .629 |
| Chris Narveson* | KCR | mr | 28 | 4 | 0 | .000 | 0 | 1 | .250 | 19 | 4.8 | 19 | 8 | .421 | 39.0 | .630 |
| Joe Nelson | Bos | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 5 | .192 | 24.2 | .563 |
| Fu-Te Ni* | Bal | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 12.2 | .639 |
| Jonathon Niese* | ChW | sp | 23 | 8 | 0 | .000 | 0 | 3 | .375 | 54 | 6.8 | 11 | 1 | .091 | 87.3 | .590 |
| Fernando Nieve | LAA | sp | 27 | 11 | 0 | .000 | 0 | 3 | .273 | 40 | 3.6 | 12 | 8 | .667 | 85.6 | .586 |
| Dustin Nippert | ChW | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 | 20.2 | .618 |
| Bud Norris | Tor | sp | 25 | 10 | 1 | .100 | 0 | 4 | .400 | 75 | 7.5 | 15 | 8 | .533 | 94.3 | .592 |
| Hideki Okajima* | Was | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 6 | .143 | 15.0 | .644 |
| Garrett Olson* | LAA | mr | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 13 | 3 | .231 | 29.4 | .582 |
| Russ Ortiz | Sea | sp | 36 | 17 | 1 | .059 | 1 | 8 | .471 | 101 | 5.9 | 16 | 5 | .313 | 86.6 | .609 |
| Vicente Padilla | KCR | sp | 32 | 29 | 1 | .034 | 0 | 17 | .586 | 131 | 4.5 | 25 | 11 | .440 | 97.8 | .626 |
| Jonathan Papelbon | Min | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 17.6 | .623 |
| Chan Ho Park | NYY | mr | 37 | 2 | 0 | .000 | 0 | 1 | .500 | 20 | 10.0 | 20 | 3 | .150 | 42.9 | .626 |
| Carl Pavano | Bal | sp | 34 | 32 | 3 | .094 | 0 | 15 | .469 | 170 | 5.3 | 17 | 12 | .706 | 101.7 | .661 |
| Jake Peavy | Oak | sp | 29 | 20 | 5 | .250 | 0 | 8 | .400 | 117 | 5.8 | 15 | 6 | .400 | 109.2 | .633 |
| Tony Pena | Oak | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 20.9 | .661 |
| Hayden Penn | Oak | mr | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 1 | 1 | 1.000 | 78.0 | .558 |
| Chris Perez | Mtl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 | 18.9 | .593 |
| Oliver Perez* | LAA | sp | 28 | 19 | 0 | .000 | 0 | 3 | .158 | 82 | 4.3 | 20 | 3 | .150 | 97.8 | .540 |
| Glen Perkins* | Oak | sp | 27 | 20 | 0 | .000 | 0 | 6 | .300 | 66 | 3.3 | 13 | 8 | .615 | 93.9 | .660 |
| Joel Pineiro | Bos | sp | 31 | 8 | 3 | .375 | 2 | 3 | .375 | 32 | 4.0 | 5 | 2 | .400 | 98.0 | .685 |
| Rick Porcello | ChW | sp | 21 | 31 | 2 | .065 | 1 | 16 | .516 | 163 | 5.3 | 25 | 5 | .200 | 102.9 | .634 |
| David Purcey* | ChW | sp | 28 | 19 | 0 | .000 | 0 | 2 | .105 | 115 | 6.1 | 27 | 10 | .370 | 87.3 | .573 |
| Horacio Ramirez* | Sea | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 5 | 2 | .400 | 19.7 | .581 |
| Ramon Ramirez | Oak | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 20.3 | .617 |
| Ramon Ramirez | Mtl | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 20.7 | .592 |
| Chris Ray | Mtl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 24.8 | .640 |
| Robert Ray | Bal | sp | 26 | 5 | 2 | .400 | 0 | 2 | .400 | 29 | 5.8 | 3 | 1 | .333 | 84.5 | .629 |
| Tim Redding | Bos | sp | 32 | 14 | 0 | .000 | 0 | 6 | .429 | 43 | 3.1 | 12 | 4 | .333 | 83.6 | .612 |
| Chad Reineke | Mtl | sp | 28 | 2 | 0 | .000 | 0 | 0 | .000 | 2 | 1.0 | 4 | 1 | .250 | 108.0 | .593 |
| Dennys Reyes* | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 11 | .333 | 19.0 | .591 |
| Arthur Rhodes* | Tor | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 12 | .400 | 19.1 | .604 |
| Clayton Richard* | Tex | sp | 26 | 30 | 0 | .000 | 0 | 10 | .333 | 110 | 3.7 | 31 | 11 | .355 | 89.6 | .585 |
| Scott Richmond | Min | sp | 30 | 6 | 1 | .167 | 0 | 4 | .667 | 35 | 5.8 | 4 | 0 | .000 | 65.5 | .613 |
| Juan Rincon | NYY | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.4 | .557 |
| Mariano Rivera | LAA | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 17.3 | .687 |
| Nate Robertson* | Bos | mr | 32 | 15 | 1 | .067 | 0 | 7 | .467 | 57 | 3.8 | 15 | 10 | .667 | 82.1 | .609 |
| Francisco Rodriguez | Tor | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 1 | .067 | 22.4 | .610 |
| Henry Rodriguez | LAA | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 3 | 1.000 | 40.5 | .556 |
| Rafael Rodriguez | Tor | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 28.5 | .667 |
| Esmil Rogers | KCR | sp | 24 | 3 | 0 | .000 | 0 | 1 | .333 | 7 | 2.3 | 3 | 2 | .667 | 69.7 | .574 |
| Ricky Romero* | Cle | sp | 25 | 30 | 2 | .067 | 2 | 10 | .333 | 153 | 5.1 | 33 | 14 | .424 | 95.6 | .598 |
| Sergio Romo | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 24.8 | .585 |
| Carlos Rosa | ChW | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 0 | .000 | 12.4 | .598 |
| Leo Rosales | Tor | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 0 | .000 | 25.2 | .645 |
| Ryan Rowland-Smith* | Det | sp | 27 | 16 | 1 | .063 | 0 | 6 | .375 | 69 | 4.3 | 12 | 8 | .667 | 85.6 | .627 |
| B.J. Ryan* | Tor | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 24.6 | .561 |
| Marc Rzepczynski* | Det | sp | 24 | 14 | 1 | .071 | 0 | 10 | .714 | 49 | 3.5 | 11 | 7 | .636 | 98.5 | .596 |
| C.C. Sabathia* | Oak | sp | 29 | 34 | 8 | .235 | 4 | 24 | .706 | 141 | 4.1 | 18 | 7 | .389 | 117.6 | .646 |
| Brian Sanches | Det | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 3 | .150 | 28.6 | .626 |
| Ervin Santana |   | sp | 27 | 27 | 3 | .111 | 0 | 10 | .370 | 119 | 4.4 | 18 | 10 | .556 | 88.1 | .619 |
| Johan Santana* | Sea | sp | 31 | 29 | 7 | .241 | 3 | 15 | .517 | 157 | 5.4 | 15 | 3 | .200 | 117.6 | .639 |
| Dennis Sarfate | NYY | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 20.0 | .625 |
| Joe Saunders* | LAA | sp | 29 | 31 | 1 | .032 | 1 | 15 | .484 | 139 | 4.5 | 14 | 5 | .357 | 93.8 | .626 |
| Max Scherzer | Tor | sp | 25 | 30 | 1 | .033 | 0 | 10 | .333 | 146 | 4.9 | 24 | 11 | .458 | 100.4 | .623 |
| Daniel Schlereth* | Det | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 35.9 | .536 |
| George Sherrill* | KCR | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 17.4 | .636 |
| Brian Shouse* | Bal | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 14.1 | .655 |
| Tony Sipp* | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 16.9 | .566 |
| Doug Slaten* | Tex | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 23.3 | .614 |
| Kevin Slowey | Tor | sp | 26 | 20 | 0 | .000 | 0 | 6 | .300 | 89 | 4.4 | 15 | 8 | .533 | 96.9 | .658 |
| Joe Smith | Tor | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 23.8 | .597 |
| John Smoltz | Mtl | sp | 43 | 19 | 0 | .000 | 0 | 8 | .421 | 64 | 3.4 | 10 | 0 | .000 | 94.2 | .673 |
| Ian Snell | Tex | sp | 28 | 31 | 1 | .032 | 0 | 14 | .452 | 153 | 4.9 | 20 | 13 | .650 | 97.1 | .599 |
| Rafael Soriano | NYY | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 17.4 | .630 |
| Jorge Sosa | Det | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 25.0 | .560 |
| Justin Speier | Mtl | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 21.2 | .629 |
| Russ Springer | Tor | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 7 | .269 | 22.4 | .651 |
| Craig Stammen | Tex | sp | 26 | 23 | 4 | .174 | 1 | 13 | .565 | 126 | 5.5 | 10 | 4 | .400 | 92.5 | .657 |
| Mitch Stetter* | Was | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 6 | .214 | 11.1 | .579 |
| Jeff Stevens | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.5 | .622 |
| Brian Stokes | Was | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 11 | .262 | 15.1 | .584 |
| Jeff Suppan | Bal | sp | 35 | 28 | 0 | .000 | 0 | 9 | .321 | 152 | 5.4 | 22 | 7 | .318 | 91.8 | .594 |
| Ken Takahashi* | Oak | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 21.5 | .568 |
| Brian Tallet* | Oak | sp | 32 | 30 | 0 | .000 | 0 | 14 | .467 | 149 | 5.0 | 22 | 7 | .318 | 98.3 | .605 |
| Julian Tavarez | Oak | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 29.6 | .569 |
| Dale Thayer | Mtl | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 50.5 | .728 |
| Rich Thompson | Mtl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 42.1 | .655 |
| Brett Tomko | Cle | mr | 37 | 10 | 0 | .000 | 0 | 4 | .400 | 51 | 5.1 | 6 | 4 | .667 | 76.5 | .660 |
| Ramon Troncoso | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 23.6 | .629 |
| Jose Valverde | KCR | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 18.7 | .601 |
| Jason Vargas* | Bal | sp | 27 | 14 | 0 | .000 | 0 | 6 | .429 | 77 | 5.5 | 13 | 5 | .385 | 79.4 | .658 |
| Donald Veal* | LAA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 27.9 | .487 |
| Justin Verlander | Cle | sp | 27 | 35 | 3 | .086 | 2 | 23 | .657 | 153 | 4.4 | 26 | 7 | .269 | 104.9 | .656 |
| Ron Villone* | Tex | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 8 | .444 | 25.7 | .590 |
| Luis Vizcaino | ChW | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 0 | .000 | 12.0 | .574 |
| Edinson Volquez | Mtl | sp | 26 | 13 | 1 | .077 | 1 | 5 | .385 | 56 | 4.3 | 12 | 2 | .167 | 101.7 | .551 |
| Chris Volstad | KCR | sp | 23 | 29 | 0 | .000 | 0 | 14 | .483 | 142 | 4.9 | 15 | 4 | .267 | 93.7 | .612 |
| Billy Wagner* | Tor | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 26.5 | .604 |
| Tim Wakefield | Min | sp | 43 | 25 | 3 | .120 | 0 | 16 | .640 | 155 | 6.2 | 17 | 10 | .588 | 103.5 | .611 |
| Tyler Walker | Min | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 22.2 | .635 |
| Jarrod Washburn* | Bos | sp | 35 | 29 | 3 | .103 | 1 | 14 | .483 | 122 | 4.2 | 20 | 7 | .350 | 95.6 | .642 |
| David Weathers | Oak | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 27.0 | .591 |
| Jeff Weaver | Was | mr | 33 | 8 | 1 | .125 | 1 | 5 | .625 | 42 | 5.3 | 9 | 2 | .222 | 72.8 | .659 |
| Brandon Webb | NYY | sp | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 2 | 1 | .500 | 31.0 | .516 |
| Ryan Webb | Was | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 19.8 | .635 |
| Todd Wellemeyer | Det | sp | 31 | 24 | 1 | .042 | 1 | 5 | .208 | 95 | 4.0 | 22 | 7 | .318 | 74.4 | .602 |
| Randy Williams* | Mtl | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 7 | .467 | 16.3 | .571 |
| Dontrelle Willis* | Mtl | sp | 28 | 3 | 0 | .000 | 0 | 0 | .000 | 3 | 1.0 | 0 | 0 | .000 | 69.3 | .577 |
| C.J. Wilson* | KCR | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 9 | .265 | 25.2 | .589 |
| Randy Wolf* | ChW | sp | 33 | 34 | 1 | .029 | 0 | 17 | .500 | 159 | 4.7 | 29 | 11 | .379 | 104.6 | .633 |
| Kerry Wood | Det | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 20.9 | .611 |
| Tim Wood | KCR | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 33.6 | .622 |
| Michael Wuertz | Tex | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 22.9 | .644 |
| Yasuhiko Yabuta | Cle | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 18.8 | .628 |
| Clay Zavada* | Mtl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 22.0 | .628 |
| Brad Ziegler | NYY | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 18.9 | .629 |
| Jordan Zimmermann | Bal | sp | 24 | 20 | 1 | .050 | 0 | 11 | .550 | 89 | 4.4 | 11 | 1 | .091 | 107.6 | .624 |
| Barry Zito* | ChW | sp | 32 | 32 | 1 | .031 | 0 | 15 | .469 | 175 | 5.5 | 27 | 11 | .407 | 103.8 | .605 |
| Joel Zumaya | NYY | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 23.8 | .529 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | NP/G | STR% |
| Jeremy Accardo | ChW | mr | 28 | 5 | 3 | .600 | 1 | .200 | 7 | 29 | 5 | .172 | 32 | 32 | 8 | 12.4 | .596 |
| Alfredo Aceves | Was | mr | 27 | 11 | 6 | .545 | 5 | .455 | 17 | 54 | 21 | .389 | 60 | 60 | 20 | 23.2 | .686 |
| Nick Adenhart | Bal | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 92.4 | .597 |
| Jeremy Affeldt* | NYY | mr | 31 | 5 | 1 | .200 | 3 | .600 | 19 | 42 | 14 | .333 | 53 | 53 | 16 | 17.4 | .594 |
| Matt Albers | Tex | mr | 27 | 5 | 3 | .600 | 2 | .400 | 2 | 37 | 15 | .405 | 45 | 45 | 18 | 30.1 | .591 |
| Jose Arredondo | Cle | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 10 | 12 | 2 | .167 | 31 | 31 | 6 | 17.2 | .610 |
| Jose Ascanio | Bal | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 6 | 6 | 2 | 24.3 | .637 |
| John Axford | Cle | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 1 | .333 | 5 | 5 | 3 | 27.2 | .537 |
| Burke Badenhop | KCR | mr | 27 | 4 | 2 | .500 | 2 | .500 | 2 | 21 | 7 | .333 | 32 | 31 | 17 | 37.3 | .636 |
| Danys Baez | Min | mr | 32 | 10 | 5 | .500 | 5 | .500 | 8 | 50 | 7 | .140 | 53 | 53 | 19 | 19.2 | .632 |
| Homer Bailey | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 97.8 | .603 |
| John Bale* | Sea | mr | 36 | 1 | 1 | 1.000 | 0 | .000 | 2 | 14 | 4 | .286 | 22 | 22 | 6 | 22.5 | .544 |
| Josh Banks | Mtl | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 1 | 56.0 | .719 |
| Daniel Bard | Tor | mr | 25 | 8 | 5 | .625 | 3 | .375 | 6 | 34 | 8 | .235 | 45 | 45 | 22 | 24.7 | .590 |
| Brian Bass | LAA | mr | 28 | 4 | 2 | .500 | 2 | .500 | 1 | 47 | 20 | .426 | 51 | 51 | 26 | 35.1 | .616 |
| Miguel Batista | Bal | mr | 39 | 3 | 2 | .667 | 1 | .333 | 2 | 35 | 9 | .257 | 52 | 52 | 14 | 28.3 | .603 |
| Josh Beckett | KCR | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 106.9 | .635 |
| Joe Beimel* |   | mr | 33 | 7 | 3 | .429 | 2 | .286 | 8 | 42 | 13 | .310 | 49 | 49 | 16 | 16.4 | .635 |
| Trevor Bell | LAA | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 86.6 | .601 |
| Kris Benson | Oak | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 109.2 | .589 |
| Brad Bergesen | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 99.5 | .656 |
| Jason Berken | Oak | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 83.6 | .629 |
| Rafael Betancourt | NYY | mr | 35 | 3 | 2 | .667 | 0 | .000 | 6 | 13 | 1 | .077 | 16 | 16 | 3 | 15.8 | .621 |
| Jerry Blevins* | Mtl | mr | 26 | 2 | 1 | .500 | 1 | .500 | 3 | 20 | 4 | .200 | 24 | 24 | 9 | 18.6 | .638 |
| Mitchell Boggs | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 21 | 1 | 0 | 79.5 | .550 |
| Blaine Boyer | ChW | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 2 | .200 | 15 | 15 | 8 | 22.1 | .575 |
| Dallas Braden* | Mtl | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 103.2 | .650 |
| Doug Brocail | Det | mr | 43 | 1 | 0 | .000 | 0 | .000 | 0 | 24 | 5 | .208 | 20 | 20 | 6 | 28.9 | .527 |
| Brian Bruney | ChW | mr | 28 | 5 | 3 | .600 | 2 | .400 | 5 | 28 | 10 | .357 | 33 | 33 | 16 | 17.2 | .583 |
| Clay Buchholz | Cle | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 103.9 | .621 |
| Jason Bulger | KCR | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 7 | 33 | 10 | .303 | 50 | 50 | 16 | 24.3 | .603 |
| Madison Bumgarner* | Sea | mr | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 93.8 | .604 |
| Greg Burke | Tex | mr | 27 | 3 | 1 | .333 | 2 | .667 | 1 | 24 | 10 | .417 | 36 | 36 | 16 | 25.4 | .618 |
| Tim Byrdak* | Bos | mr | 36 | 11 | 3 | .273 | 4 | .364 | 7 | 53 | 13 | .245 | 45 | 45 | 17 | 23.3 | .582 |
| Kiko Calero | ChW | mr | 35 | 20 | 13 | .650 | 6 | .300 | 12 | 61 | 16 | .262 | 59 | 59 | 26 | 19.8 | .601 |
| Kevin Cameron | Min | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 4 | .400 | 7 | 7 | 3 | 14.4 | .653 |
| Shawn Camp | Det | mr | 34 | 3 | 1 | .333 | 2 | .667 | 4 | 50 | 23 | .460 | 56 | 56 | 16 | 33.3 | .615 |
| Matt Capps | Sea | cl | 26 | 4 | 1 | .250 | 3 | .750 | 5 | 38 | 11 | .289 | 43 | 43 | 11 | 31.0 | .642 |
| Chris Carpenter | NYY | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 113.6 | .661 |
| Alberto Castillo* |   | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 2 | .286 | 9 | 9 | 3 | 16.9 | .592 |
| Brett Cecil* | Tor | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 95.2 | .600 |
| Jhoulys Chacin | Cle | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 94.2 | .550 |
| Bruce Chen* | Cle | sp | 33 | 1 | 0 | .000 | 0 | .000 | 3 | 12 | 6 | .500 | 25 | 20 | 10 | 35.3 | .607 |
| Randy Choate* | Min | mr | 34 | 2 | 1 | .500 | 1 | .500 | 10 | 26 | 3 | .115 | 32 | 32 | 4 | 15.7 | .635 |
| Tyler Clippard | Sea | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 8 | 38 | 15 | .395 | 43 | 43 | 15 | 31.8 | .580 |
| Phil Coke* | Bal | mr | 27 | 3 | 0 | .000 | 2 | .667 | 11 | 45 | 14 | .311 | 58 | 58 | 17 | 15.5 | .642 |
| Bartolo Colon | Was | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 93.9 | .627 |
| Roman Colon | Cle | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 4 | 35 | 19 | .543 | 42 | 42 | 16 | 21.9 | .611 |
| Roy Corcoran | Det | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 4 | 4 | 0 | 33.3 | .466 |
| Francisco Cordero | Tex | cl | 35 | 24 | 17 | .708 | 7 | .292 | 5 | 31 | 13 | .419 | 59 | 59 | 35 | 19.5 | .591 |
| Lance Cormier | Det | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 0 | 47 | 14 | .298 | 50 | 50 | 21 | 29.0 | .640 |
| Kevin Correia | Mtl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 95.1 | .616 |
| Juan Cruz | Cle | mr | 31 | 0 | 0 | .000 | 0 | .000 | 13 | 30 | 11 | .367 | 48 | 48 | 12 | 20.4 | .596 |
| Johnny Cueto | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 98.3 | .617 |
| John Danks* | NYY | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 105.1 | .617 |
| Wade Davis | Min | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 98.0 | .641 |
| Jorge de la Rosa* | Was | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 109.1 | .610 |
| Manny Delcarmen | Cle | mr | 28 | 53 | 43 | .811 | 10 | .189 | 0 | 25 | 5 | .200 | 65 | 65 | 59 | 16.7 | .579 |
| Ryan Dempster | LAA | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 103.2 | .616 |
| R.A. Dickey | LAA | mr | 35 | 0 | 0 | .000 | 0 | .000 | 1 | 33 | 10 | .303 | 38 | 36 | 8 | 38.2 | .608 |
| Mark DiFelice | Bos | mr | 33 | 3 | 2 | .667 | 1 | .333 | 2 | 25 | 9 | .360 | 24 | 24 | 11 | 28.0 | .664 |
| Brendan Donnelly | Bos | mr | 38 | 3 | 2 | .667 | 1 | .333 | 6 | 16 | 3 | .188 | 20 | 20 | 7 | 22.0 | .655 |
| Octavio Dotel | Bal | mr | 36 | 6 | 0 | .000 | 5 | .833 | 17 | 49 | 23 | .469 | 67 | 67 | 19 | 18.0 | .582 |
| Scott Downs* | Min | mr | 34 | 3 | 1 | .333 | 2 | .667 | 11 | 46 | 12 | .261 | 42 | 42 | 8 | 15.6 | .654 |
| Brian Duensing* | Bal | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 106.4 | .648 |
| Zach Duke* | Tor | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 31 | 1 | 1 | 93.4 | .646 |
| Scott Elbert* | Cle | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 2 | .250 | 14 | 14 | 4 | 14.9 | .646 |
| Kelvim Escobar | Mtl | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 84.6 | .556 |
| Dana Eveland* | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 90.5 | .583 |
| Scott Eyre* | Det | mr | 38 | 9 | 3 | .333 | 4 | .444 | 5 | 29 | 9 | .310 | 40 | 40 | 18 | 22.4 | .554 |
| Alfredo Figaro | NYY | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 3 | 3 | 0 | 50.7 | .625 |
| Doug Fister | Bos | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 92.4 | .624 |
| Randy Flores* | Mtl | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 3 | 3 | 1 | 15.7 | .532 |
| Josh Fogg | Bos | mr | 33 | 2 | 2 | 1.000 | 0 | .000 | 1 | 12 | 1 | .083 | 22 | 22 | 11 | 34.5 | .619 |
| Ryan Franklin | LAA | cl | 37 | 6 | 3 | .500 | 2 | .333 | 16 | 26 | 2 | .077 | 50 | 50 | 19 | 21.2 | .637 |
| Lucas French* | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 80.1 | .596 |
| Ernesto Frieri | Mtl | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 1 | 9.0 | .889 |
| Jaime Garcia* | Sea | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 90.0 | .559 |
| Matt Garza | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 112.5 | .622 |
| Chad Gaudin | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 33 | 4 | 4 | 89.8 | .591 |
| Josh Geer | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 86.2 | .683 |
| Edgar Gonzalez | NYY | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 4 | 4 | 2 | 44.8 | .603 |
| Gio Gonzalez* | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 95.4 | .593 |
| Mike Gonzalez* | Cle | mr | 32 | 2 | 1 | .500 | 0 | .000 | 17 | 39 | 12 | .308 | 55 | 55 | 13 | 19.3 | .618 |
| Tom Gorzelanny* | Sea | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 2 | 0 | 80.6 | .619 |
| Mike Gosling* | Sea | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 11 | 2 | .182 | 13 | 13 | 5 | 30.2 | .628 |
| Sean Green | ChW | mr | 31 | 6 | 3 | .500 | 3 | .500 | 9 | 51 | 15 | .294 | 52 | 52 | 20 | 24.1 | .579 |
| Luke Gregerson | Mtl | mr | 26 | 11 | 6 | .545 | 5 | .455 | 16 | 35 | 11 | .314 | 59 | 59 | 20 | 24.3 | .653 |
| Kevin Gregg | Sea | cl | 32 | 25 | 21 | .840 | 4 | .160 | 3 | 45 | 9 | .200 | 57 | 57 | 47 | 23.5 | .628 |
| Zack Greinke | Bos | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 115.8 | .668 |
| Eddie Guardado* | LAA | mr | 39 | 1 | 0 | .000 | 1 | 1.000 | 3 | 17 | 6 | .353 | 27 | 27 | 13 | 24.6 | .620 |
| Matt Guerrier | Was | mr | 31 | 46 | 43 | .935 | 3 | .065 | 3 | 39 | 10 | .256 | 65 | 65 | 54 | 18.4 | .656 |
| Charlie Haeger | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 107.1 | .603 |
| Jason Hammel | ChW | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 31 | 1 | 0 | 96.5 | .658 |
| Mike Hampton* | Cle | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 92.6 | .632 |
| Joel Hanrahan | Tex | mr | 28 | 4 | 1 | .250 | 2 | .500 | 5 | 44 | 18 | .409 | 48 | 48 | 20 | 21.4 | .590 |
| Tommy Hanson | Was | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 103.3 | .616 |
| J.A. Happ* | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 94.5 | .606 |
| Aaron Harang | Tor | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 97.7 | .650 |
| Kevin Hart | Bos | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 4 | 1 | .250 | 7 | 4 | 2 | 60.0 | .557 |
| Blake Hawksworth | ChW | mr | 27 | 8 | 4 | .500 | 4 | .500 | 10 | 39 | 12 | .308 | 44 | 44 | 11 | 16.5 | .604 |
| Aaron Heilman | Sea | mr | 31 | 12 | 9 | .750 | 3 | .250 | 11 | 53 | 18 | .340 | 65 | 65 | 32 | 23.9 | .579 |
| Matt Herges | Min | mr | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 3 | 1 | 34.3 | .602 |
| David Hernandez | ChW | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 88.9 | .633 |
| Felix Hernandez | Min | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 111.4 | .633 |
| Livan Hernandez | Oak | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 96.6 | .628 |
| Shawn Hill | Det | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 66.4 | .663 |
| Trevor Hoffman | ChW | cl | 42 | 19 | 16 | .842 | 2 | .105 | 7 | 60 | 16 | .267 | 62 | 62 | 33 | 15.0 | .645 |
| J.P. Howell* | Bos | mr | 27 | 42 | 35 | .833 | 7 | .167 | 2 | 30 | 12 | .400 | 55 | 55 | 50 | 20.6 | .616 |
| Tommy Hunter | KCR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 97.4 | .648 |
| Edwin Jackson | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 106.5 | .628 |
| Steven Jackson | Det | mr | 28 | 3 | 3 | 1.000 | 0 | .000 | 7 | 29 | 13 | .448 | 35 | 35 | 15 | 26.8 | .576 |
| Zach Jackson* | Mtl | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 111.0 | .604 |
| Chris Jakubauskas | Mtl | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 12 | .857 | 27 | 15 | 6 | 63.0 | .635 |
| Bobby Jenks | KCR | cl | 29 | 10 | 6 | .600 | 4 | .400 | 15 | 46 | 12 | .261 | 52 | 52 | 22 | 17.6 | .654 |
| Waldis Joaquin | ChW | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 7 | 4 | .571 | 10 | 10 | 3 | 15.9 | .553 |
| Jim Johnson | NYY | mr | 27 | 2 | 1 | .500 | 1 | .500 | 1 | 9 | 5 | .556 | 9 | 9 | 4 | 14.6 | .634 |
| Josh Johnson | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 111.0 | .635 |
| Jair Jurrjens |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 101.4 | .607 |
| Scott Kazmir* | Bos | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 98.5 | .607 |
| Kyle Kendrick | Det | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 99.8 | .623 |
| Hong-Chih Kuo* | Bos | mr | 28 | 2 | 2 | 1.000 | 0 | .000 | 7 | 26 | 5 | .192 | 27 | 27 | 10 | 21.0 | .604 |
| John Lackey |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 103.3 | .636 |
| John Lannan* | Was | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 100.0 | .619 |
| Mat Latos | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 102.0 | .593 |
| Brandon League | Min | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 4 | 28 | 9 | .321 | 35 | 35 | 15 | 23.3 | .622 |
| Wade LeBlanc* | NYY | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 90.7 | .595 |
| Justin Lehr | Tex | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 90.7 | .632 |
| Jensen Lewis | Cle | mr | 26 | 4 | 1 | .250 | 1 | .250 | 8 | 52 | 16 | .308 | 57 | 57 | 16 | 23.1 | .592 |
| Matt Lindstrom | Sea | cl | 30 | 5 | 3 | .600 | 2 | .400 | 2 | 25 | 7 | .280 | 41 | 41 | 23 | 27.9 | .616 |
| Scott Linebrink | LAA | mr | 33 | 3 | 0 | .000 | 2 | .667 | 4 | 23 | 6 | .261 | 41 | 41 | 5 | 24.1 | .642 |
| Francisco Liriano* | Min | sp | 26 | 2 | 1 | .500 | 1 | .500 | 0 | 9 | 5 | .556 | 28 | 7 | 2 | 80.0 | .589 |
| Kyle Lohse |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 88.8 | .623 |
| Braden Looper | Tex | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 86.6 | .625 |
| Rodrigo Lopez | Sea | sp | 34 | 1 | 0 | .000 | 1 | 1.000 | 3 | 14 | 7 | .500 | 15 | 14 | 4 | 39.4 | .667 |
| Mark Lowe | Bos | mr | 27 | 5 | 1 | .200 | 3 | .600 | 8 | 28 | 10 | .357 | 43 | 43 | 14 | 26.7 | .605 |
| Paul Maholm* | NYY | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 92.8 | .636 |
| Robert Manuel | Cle | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 2 | .400 | 3 | 3 | 1 | 32.7 | .643 |
| Carlos Marmol | Bal | mr | 27 | 32 | 27 | .844 | 5 | .156 | 1 | 13 | 0 | .000 | 53 | 53 | 45 | 19.8 | .549 |
| Jason Marquis | Was | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 107.2 | .610 |
| Pedro Martinez | Was | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 84.7 | .647 |
| Shairon Martis | KCR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 16 | 1 | 1 | 87.9 | .587 |
| Justin Masterson | NYY | mr | 25 | 4 | 3 | .750 | 1 | .250 | 4 | 29 | 15 | .517 | 29 | 29 | 8 | 31.5 | .628 |
| Brian Matusz* | Tex | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 90.9 | .658 |
| Brandon McCarthy | NYY | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 91.7 | .625 |
| Kyle McClellan | Bal | mr | 26 | 5 | 2 | .400 | 2 | .400 | 10 | 58 | 19 | .328 | 69 | 69 | 30 | 18.6 | .580 |
| Seth McClung | Tor | mr | 29 | 1 | 0 | .000 | 0 | .000 | 6 | 43 | 18 | .419 | 48 | 48 | 19 | 27.3 | .562 |
| Gil Meche | KCR | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 93.6 | .599 |
| Cla Meredith | LAA | mr | 27 | 5 | 1 | .200 | 4 | .800 | 6 | 25 | 13 | .520 | 51 | 51 | 21 | 23.7 | .638 |
| Randy Messenger | Det | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 16 | 11 | .688 | 13 | 13 | 7 | 29.3 | .688 |
| Dan Meyer* | NYY | mr | 28 | 2 | 1 | .500 | 0 | .000 | 7 | 18 | 4 | .222 | 18 | 18 | 2 | 9.8 | .605 |
| Kam Mickolio | ChW | mr | 26 | 3 | 1 | .333 | 0 | .000 | 6 | 23 | 1 | .043 | 23 | 23 | 1 | 12.9 | .609 |
| Andrew Miller* | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 84.6 | .585 |
| Trever Miller* | Was | mr | 37 | 2 | 0 | .000 | 1 | .500 | 1 | 9 | 3 | .333 | 11 | 11 | 2 | 11.0 | .636 |
| Kevin Millwood |   | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.8 | .613 |
| Eric Milton* | Sea | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 100.6 | .654 |
| Zach Miner | Det | mr | 28 | 2 | 2 | 1.000 | 0 | .000 | 2 | 35 | 6 | .171 | 36 | 36 | 12 | 38.3 | .557 |
| Brandon Morrow | NYY | cl | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 9 | 5 | .556 | 20 | 10 | 4 | 62.9 | .568 |
| Clayton Mortensen | Mtl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 1 | .111 | 23 | 15 | 8 | 38.3 | .595 |
| Charlie Morton | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 80.5 | .589 |
| Guillermo Mota | NYY | mr | 36 | 7 | 3 | .429 | 1 | .143 | 12 | 15 | 5 | .333 | 45 | 45 | 19 | 17.9 | .639 |
| Jason Motte | Was | mr | 28 | 2 | 1 | .500 | 0 | .000 | 1 | 28 | 9 | .321 | 39 | 39 | 17 | 18.1 | .640 |
| Jamie Moyer* | NYY | sp | 47 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 80.0 | .625 |
| Edward Mujica | Min | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 19 | 11 | .579 | 35 | 35 | 23 | 25.4 | .677 |
| Brett Myers | Oak | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 98.4 | .629 |
| Chris Narveson* | KCR | mr | 28 | 0 | 0 | .000 | 0 | .000 | 2 | 19 | 8 | .421 | 22 | 18 | 5 | 39.0 | .630 |
| Joe Nelson | Bos | mr | 35 | 4 | 2 | .500 | 1 | .250 | 6 | 38 | 10 | .263 | 35 | 35 | 8 | 24.2 | .563 |
| Fu-Te Ni* | Bal | mr | 27 | 3 | 2 | .667 | 0 | .000 | 6 | 34 | 7 | .206 | 37 | 37 | 8 | 12.2 | .639 |
| Jonathon Niese* | ChW | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 87.3 | .590 |
| Fernando Nieve | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 85.6 | .586 |
| Dustin Nippert | ChW | sp | 29 | 6 | 3 | .500 | 0 | .000 | 8 | 45 | 5 | .111 | 62 | 62 | 21 | 20.2 | .618 |
| Bud Norris | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 1 | 0 | 94.3 | .592 |
| Hideki Okajima* | Was | mr | 34 | 6 | 2 | .333 | 3 | .500 | 13 | 58 | 9 | .155 | 70 | 70 | 19 | 15.0 | .644 |
| Garrett Olson* | LAA | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 34 | 11 | .324 | 27 | 26 | 7 | 29.4 | .582 |
| Russ Ortiz | Sea | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 1 | 0 | 86.6 | .609 |
| Vicente Padilla | KCR | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 97.8 | .626 |
| Jonathan Papelbon | Min | cl | 29 | 49 | 44 | .898 | 5 | .102 | 2 | 28 | 3 | .107 | 61 | 61 | 52 | 17.6 | .623 |
| Chan Ho Park | NYY | mr | 37 | 2 | 0 | .000 | 1 | .500 | 2 | 32 | 12 | .375 | 29 | 27 | 6 | 42.9 | .626 |
| Carl Pavano | Bal | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 33 | 1 | 1 | 101.7 | .661 |
| Jake Peavy | Oak | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 109.2 | .633 |
| Tony Pena | Oak | mr | 28 | 7 | 3 | .429 | 4 | .571 | 14 | 54 | 16 | .296 | 67 | 67 | 29 | 20.9 | .661 |
| Hayden Penn | Oak | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 78.0 | .558 |
| Chris Perez | Mtl | mr | 24 | 34 | 24 | .706 | 10 | .294 | 1 | 31 | 10 | .323 | 54 | 54 | 46 | 18.9 | .593 |
| Oliver Perez* | LAA | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 97.8 | .540 |
| Glen Perkins* | Oak | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 93.9 | .660 |
| Joel Pineiro | Bos | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 98.0 | .685 |
| Rick Porcello | ChW | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 102.9 | .634 |
| David Purcey* | ChW | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 87.3 | .573 |
| Horacio Ramirez* | Sea | mr | 30 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 3 | .750 | 11 | 10 | 3 | 19.7 | .581 |
| Ramon Ramirez | Oak | mr | 28 | 32 | 26 | .813 | 6 | .188 | 1 | 27 | 9 | .333 | 58 | 58 | 52 | 20.3 | .617 |
| Ramon Ramirez | Mtl | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 13 | 7 | .538 | 16 | 16 | 4 | 20.7 | .592 |
| Chris Ray | Mtl | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 29 | 11 | .379 | 32 | 32 | 9 | 24.8 | .640 |
| Robert Ray | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 6 | 1 | 1 | 84.5 | .629 |
| Tim Redding | Bos | sp | 32 | 1 | 1 | 1.000 | 0 | .000 | 1 | 4 | 3 | .750 | 18 | 4 | 3 | 83.6 | .612 |
| Chad Reineke | Mtl | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 108.0 | .593 |
| Dennys Reyes* | Oak | mr | 33 | 7 | 4 | .571 | 3 | .429 | 11 | 39 | 15 | .385 | 60 | 60 | 17 | 19.0 | .591 |
| Arthur Rhodes* | Tor | mr | 40 | 3 | 0 | .000 | 1 | .333 | 16 | 44 | 17 | .386 | 53 | 53 | 14 | 19.1 | .604 |
| Clayton Richard* | Tex | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 89.6 | .585 |
| Scott Richmond | Min | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 5 | 4 | 65.5 | .613 |
| Juan Rincon | NYY | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 5 | 5 | 2 | 19.4 | .557 |
| Mariano Rivera | LAA | cl | 40 | 26 | 24 | .923 | 2 | .077 | 0 | 24 | 9 | .375 | 59 | 59 | 55 | 17.3 | .687 |
| Nate Robertson* | Bos | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 1 | 82.1 | .609 |
| Francisco Rodriguez | Tor | cl | 28 | 27 | 23 | .852 | 4 | .148 | 3 | 59 | 13 | .220 | 52 | 52 | 40 | 22.4 | .610 |
| Henry Rodriguez | LAA | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 0 | 40.5 | .556 |
| Rafael Rodriguez | Tor | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 16 | 6 | .375 | 12 | 12 | 7 | 28.5 | .667 |
| Esmil Rogers | KCR | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 69.7 | .574 |
| Ricky Romero* | Cle | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 95.6 | .598 |
| Sergio Romo | Min | mr | 27 | 2 | 1 | .500 | 1 | .500 | 4 | 8 | 3 | .375 | 18 | 18 | 4 | 24.8 | .585 |
| Carlos Rosa | ChW | mr | 25 | 2 | 1 | .500 | 1 | .500 | 2 | 16 | 7 | .438 | 16 | 16 | 2 | 12.4 | .598 |
| Leo Rosales | Tor | mr | 29 | 1 | 0 | .000 | 0 | .000 | 2 | 31 | 4 | .129 | 32 | 32 | 9 | 25.2 | .645 |
| Ryan Rowland-Smith* | Det | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 85.6 | .627 |
| B.J. Ryan* | Tor | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 15 | 3 | .200 | 11 | 11 | 2 | 24.6 | .561 |
| Marc Rzepczynski* | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 98.5 | .596 |
| C.C. Sabathia* | Oak | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 117.6 | .646 |
| Brian Sanches | Det | mr | 31 | 5 | 4 | .800 | 1 | .200 | 2 | 39 | 12 | .308 | 48 | 48 | 22 | 28.6 | .626 |
| Ervin Santana |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 88.1 | .619 |
| Johan Santana* | Sea | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 117.6 | .639 |
| Dennis Sarfate | NYY | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 | 20.0 | .625 |
| Joe Saunders* | LAA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 93.8 | .626 |
| Max Scherzer | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 100.4 | .623 |
| Daniel Schlereth* | Det | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 22 | 9 | .409 | 19 | 19 | 4 | 35.9 | .536 |
| George Sherrill* | KCR | cl | 33 | 14 | 10 | .714 | 4 | .286 | 13 | 54 | 13 | .241 | 63 | 63 | 27 | 17.4 | .636 |
| Brian Shouse* | Bal | mr | 41 | 0 | 0 | .000 | 0 | .000 | 2 | 10 | 5 | .500 | 14 | 14 | 6 | 14.1 | .655 |
| Tony Sipp* | Cle | mr | 26 | 4 | 1 | .250 | 2 | .500 | 13 | 39 | 8 | .205 | 43 | 43 | 9 | 16.9 | .566 |
| Doug Slaten* | Tex | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 3 | 1 | 23.3 | .614 |
| Kevin Slowey | Tor | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 96.9 | .658 |
| Joe Smith | Tor | mr | 26 | 4 | 2 | .500 | 2 | .500 | 4 | 37 | 14 | .378 | 31 | 31 | 14 | 23.8 | .597 |
| John Smoltz | Mtl | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 94.2 | .673 |
| Ian Snell | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.1 | .599 |
| Rafael Soriano | NYY | cl | 30 | 48 | 42 | .875 | 5 | .104 | 2 | 36 | 10 | .278 | 58 | 58 | 52 | 17.4 | .630 |
| Jorge Sosa | Det | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 4 | 4 | 1 | 25.0 | .560 |
| Justin Speier | Mtl | mr | 36 | 0 | 0 | .000 | 0 | .000 | 2 | 20 | 8 | .400 | 33 | 33 | 13 | 21.2 | .629 |
| Russ Springer | Tor | mr | 41 | 2 | 2 | 1.000 | 0 | .000 | 3 | 62 | 23 | .371 | 56 | 56 | 20 | 22.4 | .651 |
| Craig Stammen | Tex | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 92.5 | .657 |
| Mitch Stetter* | Was | mr | 29 | 2 | 0 | .000 | 2 | 1.000 | 5 | 21 | 6 | .286 | 32 | 32 | 5 | 11.1 | .579 |
| Jeff Stevens | Cle | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 2 | 22.5 | .622 |
| Brian Stokes | Was | mr | 30 | 6 | 2 | .333 | 2 | .333 | 9 | 45 | 8 | .178 | 56 | 56 | 13 | 15.1 | .584 |
| Jeff Suppan | Bal | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 91.8 | .594 |
| Ken Takahashi* | Oak | mr | 41 | 1 | 1 | 1.000 | 0 | .000 | 1 | 13 | 6 | .462 | 18 | 18 | 10 | 21.5 | .568 |
| Brian Tallet* | Oak | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 98.3 | .605 |
| Julian Tavarez | Oak | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 3 | 35 | 10 | .286 | 39 | 39 | 19 | 29.6 | .569 |
| Dale Thayer | Mtl | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 4 | 4 | 3 | 50.5 | .728 |
| Rich Thompson | Mtl | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 12 | 12 | 4 | 42.1 | .655 |
| Brett Tomko | Cle | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 76.5 | .660 |
| Ramon Troncoso | Tex | mr | 27 | 5 | 4 | .800 | 1 | .200 | 4 | 43 | 13 | .302 | 64 | 64 | 17 | 23.6 | .629 |
| Jose Valverde | KCR | cl | 30 | 34 | 31 | .912 | 3 | .088 | 3 | 17 | 6 | .353 | 51 | 51 | 41 | 18.7 | .601 |
| Jason Vargas* | Bal | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 18 | 4 | 1 | 79.4 | .658 |
| Donald Veal* | LAA | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 7 | 7 | 5 | 27.9 | .487 |
| Justin Verlander | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 104.9 | .656 |
| Ron Villone* | Tex | mr | 40 | 0 | 0 | .000 | 0 | .000 | 2 | 30 | 12 | .400 | 38 | 38 | 9 | 25.7 | .590 |
| Luis Vizcaino | ChW | mr | 35 | 3 | 2 | .667 | 1 | .333 | 7 | 22 | 4 | .182 | 23 | 23 | 7 | 12.0 | .574 |
| Edinson Volquez | Mtl | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 101.7 | .551 |
| Chris Volstad | KCR | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 93.7 | .612 |
| Billy Wagner* | Tor | mr | 38 | 4 | 3 | .750 | 1 | .250 | 0 | 6 | 2 | .333 | 10 | 10 | 5 | 26.5 | .604 |
| Tim Wakefield | Min | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 103.5 | .611 |
| Tyler Walker | Min | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 6 | .600 | 11 | 11 | 4 | 22.2 | .635 |
| Jarrod Washburn* | Bos | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 95.6 | .642 |
| David Weathers | Oak | mr | 40 | 1 | 0 | .000 | 1 | 1.000 | 2 | 46 | 16 | .348 | 54 | 54 | 17 | 27.0 | .591 |
| Jeff Weaver | Was | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 0 | .000 | 13 | 5 | 4 | 72.8 | .659 |
| Brandon Webb | NYY | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 31.0 | .516 |
| Ryan Webb | Was | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 10 | 3 | .300 | 9 | 9 | 6 | 19.8 | .635 |
| Todd Wellemeyer | Det | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 74.4 | .602 |
| Randy Williams* | Mtl | mr | 34 | 0 | 0 | .000 | 0 | .000 | 3 | 9 | 2 | .222 | 15 | 15 | 2 | 16.3 | .571 |
| Dontrelle Willis* | Mtl | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 69.3 | .577 |
| C.J. Wilson* | KCR | mr | 29 | 3 | 2 | .667 | 0 | .000 | 10 | 45 | 12 | .267 | 57 | 57 | 16 | 25.2 | .589 |
| Randy Wolf* | ChW | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 104.6 | .633 |
| Kerry Wood | Det | cl | 33 | 21 | 13 | .619 | 8 | .381 | 1 | 35 | 8 | .229 | 43 | 43 | 36 | 20.9 | .611 |
| Tim Wood | KCR | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 3 | .429 | 13 | 13 | 6 | 33.6 | .622 |
| Michael Wuertz | Tex | mr | 31 | 15 | 10 | .667 | 5 | .333 | 13 | 37 | 13 | .351 | 71 | 71 | 35 | 22.9 | .644 |
| Yasuhiko Yabuta | Cle | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 5 | 5 | 1 | 18.8 | .628 |
| Clay Zavada* | Mtl | mr | 26 | 4 | 2 | .500 | 1 | .250 | 6 | 34 | 6 | .176 | 47 | 47 | 16 | 22.0 | .628 |
| Brad Ziegler | NYY | mr | 30 | 6 | 4 | .667 | 2 | .333 | 8 | 34 | 11 | .324 | 35 | 35 | 17 | 18.9 | .629 |
| Jordan Zimmermann | Bal | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 107.6 | .624 |
| Barry Zito* | ChW | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.8 | .605 |
| Joel Zumaya | NYY | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 1 | 11 | 2 | .182 | 19 | 19 | 8 | 23.8 | .529 |